Not exact matches
Roche has four biologic cancer
immunotherapy molecules in clinical
trials that could work in powerful combinations with each
other or with current drugs, says William Pao, global head of oncology discovery in Basel.
While clinical
trials of such
immunotherapies in
other cancers have shown them to be highly effective in a subgroup of patients, the new study stands out because nearly all patients benefited from the treatment.
More than 500 clinical
trials are underway to explore the impact of these and
other checkpoint inhibitors on a dozen varieties of cancer, alone or with
other immunotherapies, as well as conventional treatments.
The
immunotherapy drug pembrolizumab — already FDA - approved for
other forms of cancer - has been found to be effective in patients with metastatic triple negative breast cancer, according to an international clinical
trial led by NYU Langone's Perlmutter Cancer Center.
To search for
other characteristics of ccRCC tumors that influences
immunotherapy response or resistance, the researchers used whole - exome DNA sequencing to analyze tumor samples from 35 patients treated in a clinical
trial with the checkpoint blocker nivolumab (Opdivo).
Wherry, together with his colleagues in the Parker Institute for Cancer
Immunotherapy at Penn, are involved in multiple checkpoint - related
trials, in melanoma, lung cancer, renal cell carcinoma, and
others, including combining checkpoint blockade with radiation.
NEW YORK AND SAN DIEGO (Sept. 3, 2014)-- The nonprofits Ludwig Cancer Research (Ludwig) and the Cancer Research Institute (CRI) announced today an agreement with VentiRx Pharmaceuticals Inc., a clinical stage biopharmaceutical company, to conduct a clinical
trial with motolimod (VTX - 2337) combined with
other immunotherapy agents available to Ludwig and CRI through
other industry partnerships.
Jess searched for clinical
trials, typing in «
immunotherapy» and
other terms she'd heard the doctors use.
Upcoming interventional
trials will examine
immunotherapy in combination with
other novel agents in an effort to improve both short - and long - term outcomes for patients.
The TCE hosts an annual retreat (PDF) to review recently completed, ongoing, and planned lung cancer
immunotherapy trials, as well as
other related studies and to host an outside invited speaker.
In addition, a growing number of
immunotherapy clinical
trials are in place to test this groundbreaking approach on
other cancers like lymphoma, multiple myeloma, and for solid tumors, through
trials in glioblastoma, mesothelioma, and ovarian and pancreatic cancer.
The Kimmel Cancer Center also participates in
other cancer clinical
trials consortia, including those for prostate, breast, and bone marrow cancers,
immunotherapy, and the Hoosier Cancer Research Network.
Rutgers Cancer Institute along with its partner RWJBarnabas Health, offers patients access to the most advanced treatment options including clinical
trials and novel therapeutics such as precision medicine, and
immunotherapy — many of which are not available at
other facilities across the state.
Most recently, CRI has launched a new «venture philanthropy» program called the Cancer Vaccine Acceleration Fund (CVAF) as a means to catalyze development of next - generation therapeutic cancer vaccines and
other immunotherapies by helping to address the critical shortage of capital available for early stage clinical
trials.
If clinical
trials of anti-PD-1 continue to show promising results, cancer patients may soon have access to another powerful
immunotherapy for the treatment of numerous cancers, including melanoma, non-small cell lung cancer, and
other solid tumors.
Hopefully, a further
trial will prove the potential of LTCI as a major medical breakthrough in the field of
immunotherapy, not only as has been shown for cats, but also to help control
other inflammatory diseases in dogs, like arthritis, and EPM, endotoxemia, and laminitis in horses.»