Not exact matches
«Gene - delivery system prevents vision loss from
inherited eye disease: Initial testing in animal models holds promise for treating Leber congenital amauroisis and
other congenital visual disorders.»
Genes, alone or in combination, determine what features a person
inherits from his or her parents, such as blood type, hair color,
eye color and
other characteristics, including risks of developing certain
diseases.
If a parent has bone or joint
disease, allergic skin
disease, bad teeth and gums, ear infections,
eye problems, separation anxiety, destructive behavior, tender feet (cutting toe nails), oily musty skin odor, coprophagy, liver, heart or kidney
disease, bladder stones, asthma, fatty tumors, poor physique or coordination, umbilical and
other hernias or another
disease, then the puppy is at least ten times as likely to
inherit these problems than a puppy from healthier parents.
Failure to do annual
eye exams through at least 10 years of age, or assuming that any retinal defect found can't be
inherited because the dog or its parents have cleared the prcd test has the potential to result in increased frequency of those
other and presently rare forms of retinal
disease because breeders are makng mating choices based on false assumptions.
It should be noted that many breeds of dog are known to carry multiple forms of
inherited retinal
disease and the DNA test will not replace the need to remain vigilant for
other forms of
inherited eye disease in the breed.
This number far exceeds those associated with any
other category of
disease, meaning that
inherited eye diseases are arguably better understood, at both the clinical and genetic level, than any
other category of canine
disease.
Responsible breeders will routinely check their dogs for the onset of various
inherited disorders, these commonly include (but are not limited to): CERF examinations on
eyes, OFA patellar examinations, OFA thyroid function panels, von Willebrand's factor, OFA hip and Legg - Perthes
disease x-rays, and
others.
The European College of Veterinary Ophthalmologists (ECVO) Scheme (http://www.ecvo.org/) is in use in seven European countries, and individual ECVO Diplomates work in accordance with the scheme in
other countries to control presumed
inherited diseases of the
eye and its adnexa.
The three schemes listed above, and
other comparable schemes in place around the world, differ incrementally from one another in the precise ways in which they are operated, but they all serve to document and register dogs affected with, and free from,
inherited eye diseases.