Sentences with phrase «other key protein»

The treatment reduced the observed symptoms of anaphylaxis, and lowered other key protein markers in the allergic response by up to 90 per cent.

Not exact matches

U.S. whey proteins are well known as a key component of training regimens for competitive body builders and other professional athletes.

Key product lines are Gellan Gum, Pectin, Cellulose Gum, Xanthan Gum, Carrageenan, Carboxymethyl Cellulose, Diutan Gum and Microparticulated Whey Protein Concentrate, as well as other unique biopolymers.

This is key since whey is a complete protein that releases quickly into your system and tends to react differently than some other available protein sources.

Here are 10 delicious vegetarian - friendly recipes that pack in the protein and other key nutrients.

Staring down a wall with whey, casein, soy, hemp, rice and even pea proteins divided up in isolates, concentrates, hydrolysates and tons of other varieties, people often having difficulty with one key question: Which protein powder is best for me?

Stay Fit Dining meals provide a minimum 1/3 of the vitamins, minerals, protein, and other key nutrients as defined by the Department of Agriculture's Recommended Daily Requirements (RDA) for people over age 60.

However, human and placozoan versions of p53 share key features, including regions that allow it to attach to DNA and other proteins.

«Viral protein in their sights: Advanced imaging reveals key structure of Ebola and other RNA viruses.»

Myers and other researchers have found atmospheric CO2 levels predicted for mid-century — around 550 parts per million — could make food crops lose enough of those key nutrients to cause a protein deficiency in an estimated 150 million people and a zinc deficit in an additional 150 million to 200 million.

Escherichia coli and many other bacteria produce cellulose as a key component of the extracellular matrix that coats the cells to form a biofilm, a complex multicellular community consisting of numerous bacteria, exopolysaccharides (like cellulose), protein fibers, and DNA (4 — 6).

This «RNA world» theory has been bolstered by evidence that some RNA molecules can duplicate others — a key task normally performed by proteins (ScienceNOW, 17 May 2001).

This dimer gives microtubules directionality, which is key to many of their other properties, such as being able to assemble or disassemble from either end, and allowing motor proteins to walk along them in a specific direction.

Working with human breast cancer cells and mouse models of breast cancer, scientists identified a new protein that plays a key role in reprogramming cancer cells to migrate and invade other organs.

In a paper published this week in Current Biology, postdoctoral fellow David Kast, PhD, and professor Roberto Dominguez, PhD, and three other colleagues from the Department of Physiology at the Perelman School of Medicine at the University of Pennsylvania, show for the first time that the formation of ephemeral compartments key in this process require actin polymerization by the Arp2 / 3 complex, a composite of seven proteins.

The UPR therefore plays a key role in secretory cells but also protects other cells of the body from the stresses associated with an accumulation of unfolded or misfolded proteins.

The yolks also contain protein, along with key nutrients and other food components that are not present in egg whites, Burd said.

«The DNA - bending module of the SRY protein is preserved among a large family of regulatory proteins that regulate key events in development, including how stem cells form the brain and other organs,» said Weiss, also a Distinguished Research Professor within the medical school.

«Key protein drives «power plants» that fuel cells in heart, other key body systems: Discovery explains KLF4, mitochondrial connection in heart failure.&raqKey protein drives «power plants» that fuel cells in heart, other key body systems: Discovery explains KLF4, mitochondrial connection in heart failure.&raqkey body systems: Discovery explains KLF4, mitochondrial connection in heart failure.»

Study co-author, experimentalist Peijun Zhang of the University of Pittsburgh, aided this effort by developing a technique to purify the key proteins in the array and combine them in just the right proportions so that they assemble themselves in thin layers — allowing clearer 3 - D EM snapshots of their structural conformations and interactions with each other.

Aging is a key risk factor for sAML because, over time, hematopoietic stem cells (which give rise to all other blood cell types) accumulate DNA mutations and changes in other molecules that put DNA instructions into action, such as RNA and proteins.

Sander reasoned that as proteins fold, pairs of amino acids distant from each other on the 2D string could end up adjacent in the 3D-folded protein, providing a key interaction that allows the protein to hold its shape.

Two key events enabled organelles to develop: The precursor bacteria transferred many of their genes to the host's genome, and they developed a method of transporting the proteins produced by these and other genes back inside their own membranes.

For example, it revealed for the first time that one region of a kinase called CheA (KEY aye), changes its orientation in relation to the other proteins, in a motion the researchers call «dipping.»

All people have human leukocyte antigens (HLA), proteins that are key to the immune system's defense against bacteria, viruses and other potentially harmful invaders.

By designing synthetic proteins that can only interact with a pre-determined partner, and introducing them into cells, the team revealed a key interaction that regulates the ability of embryonic stem cells to change into other cell types.

Based on studies of other genes related to FOXP2, the authors suggest that the loss of functioning protein from one copy of this gene might disrupt the proper growth of key speech and language structures in the brain.

The mutation affects a key junction joining the palladin protein to other molecules in the complex.

He attached one end of the protein titin, thought to be a key player in muscle elasticity, to the tip of his cantilever and attached the other end to a plate.

A near - atomic level map of Zika virus shows its structure to be largely similar to that of dengue virus and other flaviviruses, but with a notable difference in one key surface protein, report scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

A key advantage of the system is that Cre acts independently of any other accessory proteins or co-factors, thus allowing for broad applications in a variety of experiments.

Known key pathological mechanisms are related to defects in structural proteins, nuclear proteins, intermediate filaments and other cyoskeletal proteins, mitochondrial energy production and ion channels, but new concepts and new genes are rapidly being identified.

«It is well - established that Alzheimer's and other neurodegenerative diseases progress from the buildup of multiple misfolded proteins, a key reason why these diseases have proven so challenging to treat,» said Richard Fisher, Ph.D., chief scientific officer of Proclara.

Congratulations to SCAHT research group leader Prof. Luigi Terracciano and other collaborators of Prof. Michael N Hall at the University of Basel on their recent Nature publication describing the discovery of protein LHPP as a key tumor suppressor...

Heat shock proteins are known to play a key role in thermal stress adaption by assisting the folding and refolding of other proteins.

[1,2] Cerebral AS pathology is also closely associated with the visual hallucinations that typify LBD, and it is becoming increasingly clear that LB along with other neuronal protein aggregates are key drivers of «normal» cognitive aging.

Key proteins involved in gene expression depend on each other when forming a heart in an embryo, but, if left alone, they start to run amok

The innate immune system is particularly amenable to characterization with expression - based methodology such as RNA - seq, as one of the key biological consequences of pathogenic infections is the rapid induction of several classes of effector proteins, along with up - regulation of a number of other pathway components.

Scientists are claiming to have zeroed in on the culprit that makes losing weight difficult for obese people, identifying a protein that stops fat cells from burning energy which they say could become a key target in treating obesity and other metabolic conditions.

Instead, FUS — Fused in Sarcoma's — protein interaction region remains forever squirmy and squiggly, the study reports, performing its healthy functions by assembling into liquid - like droplets with other copies of itself and key molecules such as RNA.

The Lexicon efforts are focused on gene families that are pharmaceutically important, such as transporters, G - protein coupled receptors (GPCRs), ion channels, kinases and other key enzymes, membrane proteins (e.g., receptors), and secreted proteins.

We and others have identified NMNAT2 (nicotinamide mononucleotide adenylyl transferase 2) as a neuroprotective protein key to maintaining neuronal integrity throughout life.

GSK3β, the first neighbour of β - catenin is a central, highly multi-functional protein known as a key protein difficult to inhibit without causing side effects and toxicity.41 In glioblastoma and NSCLC cancer, previous studies found that the decreased level of FRAT1 influences the GSK3β activity to phosphorylate β - catenin and by that, inhibit the WNT pathway.39, 40 The role of FRAT1 in colon cancer is less known but based on its function in other cancer types and its special influencing position in colon cancer signalling, we point out its relevance as a potential target in colon cancer therapy (Fig. 3d).

To understand the selection mechanism behind mutations, network - based studies were used to estimate the importance of a mutated protein compared to non-mutated ones in signalling and protein — protein interaction networks.10, 11,12,13 Proteins mutated in cancer were found having a high number of interacting partners (i.e., a high degree of connectivity), which indicates high local importance.10 Mutated proteins are also often found in the centre of the network, in key global positions, as quantified by the number of shortest paths passing through them if all proteins are connected with each other (i.e., they have high betweenness centrality; hereafter called betweenness).11, 12 Mutated proteins also have high clustering coefficients, which means their neighbours are also neighbours of each other.10, 13 Moreover, neighbourhood analysis of mutated proteins have been previously successfully used to predict novel cancer - related genes.14, 15 However, to the best of our knowledge, no study has concentrated particularly on the topological importance of first neighbours of mutated proteins in cancer, and their usefulness as drug targets theProteins mutated in cancer were found having a high number of interacting partners (i.e., a high degree of connectivity), which indicates high local importance.10 Mutated proteins are also often found in the centre of the network, in key global positions, as quantified by the number of shortest paths passing through them if all proteins are connected with each other (i.e., they have high betweenness centrality; hereafter called betweenness).11, 12 Mutated proteins also have high clustering coefficients, which means their neighbours are also neighbours of each other.10, 13 Moreover, neighbourhood analysis of mutated proteins have been previously successfully used to predict novel cancer - related genes.14, 15 However, to the best of our knowledge, no study has concentrated particularly on the topological importance of first neighbours of mutated proteins in cancer, and their usefulness as drug targets theproteins are also often found in the centre of the network, in key global positions, as quantified by the number of shortest paths passing through them if all proteins are connected with each other (i.e., they have high betweenness centrality; hereafter called betweenness).11, 12 Mutated proteins also have high clustering coefficients, which means their neighbours are also neighbours of each other.10, 13 Moreover, neighbourhood analysis of mutated proteins have been previously successfully used to predict novel cancer - related genes.14, 15 However, to the best of our knowledge, no study has concentrated particularly on the topological importance of first neighbours of mutated proteins in cancer, and their usefulness as drug targets theproteins are connected with each other (i.e., they have high betweenness centrality; hereafter called betweenness).11, 12 Mutated proteins also have high clustering coefficients, which means their neighbours are also neighbours of each other.10, 13 Moreover, neighbourhood analysis of mutated proteins have been previously successfully used to predict novel cancer - related genes.14, 15 However, to the best of our knowledge, no study has concentrated particularly on the topological importance of first neighbours of mutated proteins in cancer, and their usefulness as drug targets theproteins also have high clustering coefficients, which means their neighbours are also neighbours of each other.10, 13 Moreover, neighbourhood analysis of mutated proteins have been previously successfully used to predict novel cancer - related genes.14, 15 However, to the best of our knowledge, no study has concentrated particularly on the topological importance of first neighbours of mutated proteins in cancer, and their usefulness as drug targets theproteins have been previously successfully used to predict novel cancer - related genes.14, 15 However, to the best of our knowledge, no study has concentrated particularly on the topological importance of first neighbours of mutated proteins in cancer, and their usefulness as drug targets theproteins in cancer, and their usefulness as drug targets themselves.

A study has shown that the increase of the brain enzyme called puromycin - sensitive aminopeptidase, which is the most abundant brain peptidase seen in mammals, can slow the harmful accumulation of toxic tau proteins, which ultimately result in neurofibrillary tangles, a key pathological characteristic of Alzheimer's and other types of dementia.

«Also, the foods rich in omega - 3s are also rich in other key nutrients that promote health such as vitamin E [walnuts] and protein [salmon, tuna].»

Stress resistance has not been assessed however and so the biological relevance of this finding is currently unknown.32 Several IER trials (75 - 85 % ER on restricted days) in overweight / obese populations have reported reductions in various markers of oxidative stress 37, 41, which in one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directions

And for a vegan bodybuilder who must unfortunatelly play tetris with the food sources that he choses in order to give to his body the right ammounts of aminos, restricting SPI and soy foods so much does not make his goal any easier.There are sometimes that you need a meal thats complete with aminos and soy provides that meal with the additional benefits of lacking the saturated fats trans cholesterol and other endothelium inflammatory factors.I'm not saying that someone should go all the way to 200gr of SPI everyday or consuming a kilo of soy everyday but some servings of soy now and then even every day or the use of SPI which helps in positive nitrogen balance does not put you in the cancer risk team, thats just OVERexaggeration.Exercise, exposure to sunlight, vegan diet or for those who can not something as close to vegan diet, fruits and vegetables which contains lots of antioxidants and phtochemicals, NO STRESS which is the global killer, healthy social relationships, keeping your cortisol and adrenaline levels down (except the necessary times), good sleep and melatonin function, clean air, no radiation, away from procceced foods and additives like msg etc and many more that i can not even remember is the key to longevity.As long as your immune system is functioning well and your natural killer cells TP53 gene and many other cancer inhibitors are good and well, no cancer will ever show his face to you.With that logic we shouldn't eat ANY ammount of protein and we should go straight to be breatharians living only with little water and sunlight exposure cause you like it or not the raise of IGF1 is inevitable i know that raise the IGF1 sky high MAYBE is not the best thing but we are not talking about external hormones and things like this.Stabby raccoon also has a point.And even if you still worry about the consumption of soy... http://www.ncbi.nlm.nih.gov/pubmed/21711174.

Grandison et al, 2009,) Solon - Biet 2014, Nakagawa 2012 and others pointed specifically to protein restriction as the key to longevity in these animal studies.

The other key thing is to try to make sure the fat / carb / protein ratios are adhered to for each snack / meal.