Our real hope was that our gene would look like
some other known gene and give us a clue about what it did.
The researchers found 70 never - before - seen genes that, based on their resemblance to
other known genes, look to be involved in making these strains virulent.
Not exact matches
DNA - testing companies determine where your
genes are from by comparing you to
other users who are
known to have ancestors from that region.
We
know a lot of what we
know about
gene mutation and our similarities with
other animals precisely because we have been working within this paradigm for which there is a ton of evidence.
At some point, our ancestors»
genes became more successful when the ones who
knew how to reciprocate helping
others had a tendency to survive longer.
If Chad and
others argue that naturalistic evolution must be dismissed because we don't
know exactly what happened with
gene mutation and transmission frequencies during particular periods of rapid change, then how can we accept a replacement argument in which we don't even
know what happens at all?
This study led to the discovery of 18 new imprinted
genes, validated some
known genes and resolved the disputed status of some
others to provide a gold standard list of 93 imprinted
genes in mouse.
A mushroom whose
genes have been edited with molecular scissors
known as CRISPR / Cas9 doesn't need to be regulated like
other genetically modified crops, the U.S. Department of Agriculture said April 13 in a letter to the mushroom's creator.
«We've
known other people who have looked at
genes involved in brain size evolution, tested them out and done the same kinds of experiments we've done and come up dry.»
A class of small molecules found in grapes, red wine, olive oil, and
other foods extends the life of yeast cells by approximately 70 % and activates
genes known to extend life span in laboratory animals.
One area like — now again, all of these areas, you
know, have been discovered by
others — is molecular - associated biology identifying
genes that are important [in] social behavior.
«Professor Hummon and I have been mapping
gene expressions for the right versus the left side of the colon, which we now
know are different from each
other due to the way the colon forms,» said Buechler.
Inherited mutations of the tumour suppressor
gene CDKN2A are the strongest
known risk factors for familial melanoma and mutations in this
gene also increase the risk of
other cancers.
This
gene is
known to be highly active in multiple myeloma and many
other cancers, raising the possibility that strategies to shut it down could be effective against a variety of tumors.
ZNF804A also interacts with and modulates expression of
other genes known to be associated with schizophrenia.
«From
other studies ***** we
know that epigenetic modifications of the DPP4
gene, which are associated with an increased production of the enzyme, have a negative impact on the liver metabolism already in young mice, long before fatty liver disease emerges,» says Baumeier.
In fact, the FDA has ruled that because DNA is in every living organism, crops engineered with added
genes are «substantially the same» as
other foods and are
no different from crops genetically modified through conventional breeding techniques.
The
gene known as RD26 is activated, on the
other hand, when plants are challenged with drought stress, Yin said.
«For a long time now, the entire field was collecting data on MYC, LIN41, and
other genes and proteins without
knowing what most of it meant,» said Yamanaka, who is also director of the Center for iPS Cell Research and Application (CiRA) at Kyoto University, and professor at UC San Francisco.
Probably, the
genes we
know from
other animals have a different function in sponges and were co-opted later for the function we are familiar with.»
The
genes O, S, and K were
known to help the cells become pluripotent, which allows them to produce any
other cell type in the body.
Helicosporidium, on the
other hand, lost almost nothing except those
genes required for photosynthesis, which it
no longer needs as a parasite.
SIX3 and a related
gene, SIX2, with a similar pattern of expression in human beta cells, encode proteins
known as transcription factors that control the expression of many
other genes in the cell.
The researchers used «bait» proteins from over two dozen
known autism
genes, fishing in a pool of human DNA for
other proteins that would interact with the baits.
Berninger and
others have previously shown that Sox2, Ascl1, and
other transcription factors — proteins that bind to specific DNA sequences to control the activity of
genes — can induce the nonneuronal «support cells»
known as glia to turn into neurons.
Other scientists are probing the FOXP2
gene further by studying the protein it produces,
known as FOXP2.
Suspecting that the
other four carried a new Ehrlichia species, the researchers sequenced the bacterial
gene in their blood and compared it to a database containing the sequences of
known infectious bacteria.
Scientists want to
know if the virus could interact with
other factors, such as mutated
genes, to trigger the disease.
In most cases, the
genes responsible for these processes are
known as «transcription factors» — meaning that they are responsible for turning
other genes on and off.
In this research, the group looked at two variants of miR - 21, a microRNA «oncomiR»
known to target tumor suppressor
genes and which is highly expressed in a number of cancers as well as
other proliferative diseases such as psoriasis.
Histones and
other proteins, when modified by this process
known as acetylation, play critical roles in regulation of
gene expression, typically resulting in increased
gene expression.
While this phenomenon,
known as horizontal
gene transfer, is fairly common in bacteria and
other microorganisms, this was the first compelling evidence that multicellular organisms were swapping
genes.
The IL - 15R - alpha
gene is expressed in tissues
other than muscle, and no one
knows the full consequences of turning the
gene off.
«We don't
know what the time period was between the two divergences, but we do
know that half of the
genes studied suggest that chimpanzees appear to be closer to humans, while the
other half contradict this or are ambiguous.»
BRCA1 and 2,
genes whose proteins are supposed to work as tumor suppressors and also repair DNA damage, were the first
known risk factor
genes for familial breast cancer as well as ovarian and
other cancers.
If we
knew what those functions were, then maybe we'd have a better way of manipulating these cells, so I'd be keen on performing some experiments to explore what these
other genes do.
We
know that Hox
genes encode transcription factors that control the activity of
other genes, but we found that digit - innervating motor neurons also express
other genes, such as FIGN and CNEP4], and we still don't
know the function of any of these
other genes.
Dubbed Klosneuviruses, the giant virus contains a more complete set of translation machinery
genes than any
other virus
known to date.
He's eager to
know whether this same set of
genes is involved in social responsiveness of
other animals.
«Now that we
know how calcification happens and what the key nodes are, we
know what
genes to look for that might be mutated in
other related forms of cardiovascular disease.»
«We want to
know whether this fragmentation is resulting in reduced
gene flow or inbreeding or
other things that might be detrimental to the animals.
What we were surprised to find out was that the real differences we could detect in terms of when we did the swap experiments to say which yeast could outperform the
other — what we learned was that the GAL1
gene, that the part [of] that, the DNA sequence is outside of the GAL1
gene, it acts as a switch to turn up or turn down GAL1 expression, that had evolved considerably from the ancestral situation; and same for the GAL3.And then what had happened was that each function had been optimized, that GAL3 had sort have been tuned to be sort of a loosely regulated kind of available anytime sensor of galactose and GAL1 had evolved to be an incredibly tightly regulated, in fact, it's the most tightly regulated
gene you
know of in yeast.
This doubles the number of all
other genes known on the planet.
Nobody
knows if adding the interleukin - 4
gene would have the same effect in a different pathogen, but «the question instantly became what would happen if somebody tried this with smallpox or
other human viruses,» says Seamark.
When Kaufman, Zon and colleagues looked to see what was different about these early cancer cells, they found that crestin and the
other activated
genes are the same ones turned on during zebrafish embryonic development — specifically, in the stem cells that give rise to the pigment cells
known as melanocytes, within a structure called the neural crest.
This program normally shuts off after embryonic development, but occasionally — for reasons not yet
known — crestin and
other genes in the program turn back on in certain cells.
Many of these
genes are unique to flowering plants, and many are
known to be important for producing the flower as well as
other structures and
other processes specific to flowering plants.»
There are at least six
other genes in that part of the chromosome, and Forejt doesn't yet
know which one is a speciation
gene.
Archibald and
others caution that though Loki has
genes that are involved in membrane remodeling in
other organisms, no one
knows for sure that they perform the same function in Loki.
«Because TIA - 1 is
known to suppress COX - 2 expression in
other cells, we reasoned that the inactivation of the TIA - 1
gene would increase COX - 2 expression in neurons and, consequently, would increase resistance to acute seizures,» he continues.