Sentences with phrase «other microfluidic devices»

Not exact matches

As it can take weeks to grow human cells into intact differentiated and functional tissues within Organ Chips, such as those that mimic the lung and intestine, and researchers seek to understand how drugs, toxins or other perturbations alter tissue structure and function, the team at the Wyss Institute for Biologically Inspired Engineering led by Donald Ingber has been searching for ways to non-invasively monitor the health and maturity of cells cultured within these microfluidic devices over extended times.

I'd say the trend is going the other way: that the [silicon lithography] technology that has developed around the integrated circuit is now being adopted in several other areas, like microelectromechanical systems, microfluidic devices, chemical labs on a chip, and more.

«The next step will be to track a few patients over the course of their treatment, taking several blood draws to see if the data captured by the microfluidic device correlates with the data their medical team is collecting through other methods,» says Liu.

And compared to other techniques used for assisted reproductive technologies, the use of the microfluidic device resulted in significantly lower rates of DNA damage and improved sperm recovery using this method.

Microfluidic devices are tiny chips that can sort out disease biomarkers, cells and other small structures in samples like blood by using microscopic channels incorporated into the devices.

«These highly elusive 3 - nanometer structures are too small to be captured with other types of liquid biopsy devices, such as microfluidics, due to shear forces that can potentially destroy them,» he noted.

In order to develop a system that more closely replicates the metabolic differences among hepatocytes, the research team developed a microfluidic device that distributes hormones or other chemical agents across a 20 - to 40 - cell - wide sample of hepatocytes in such a way that the effects on the liver cells vary from one side to the other.

And a combination of microfluidic flow and other micro-architectural features of the devices enables the cells inside organ chips to live and thrive in three dimensions, not two.

The labelling is for acetylated tubulin in red (identifying all axons), and green for the cell permeable dye calcein, which is only applied on the axonal side of the chambers (top half) and allows the identification of those neuronal cell bodies (bottom half) that have extended axons to the other side of the microfluidic device.

«Our technology will provide significantly higher forces and faster impact cycles than have previously been possible, and by building these tools onto microfluidic devices, we can leverage a host of other on - chip diagnostics and imaging tools and can collect the cells after testing for longer - term studies,» said Valentine.