Sentences with phrase «other neoplasms»

Heterozygous somatic mutations affecting the spliceosome gene SF3B1 drive age - related clonal hematopoiesis, myelodysplastic syndromes (MDS) and other neoplasms.

Soft - Tissue Sarcomas, Breast Cancer, and other Neoplasms.

Not exact matches

First author Michele T. Yip - Schneider, Ph.D., associate research professor of surgery, and senior author C. Max Schmidt, M.D., Ph.D., MBA, professor of surgery, biochemistry and molecular biology, report this is the first cyst fluid protein biomarker that can differentiate serous cystic neoplasms, a benign type of cystic lesion, from all other cancerous or precancerous cystic lesions without surgery.

Other similar but truly Ph - negative conditions are considered CML - like myeloproliferative neoplasms.

BAFF Levels Are Elevated in Paediatric Patients With Acute Lymphoblastic Leukaemia Compared to Other B - Lineage Neoplasms

Supportive care is given to treat problems caused by multiple myeloma and other plasma cell neoplasms.

Several types of targeted therapy may be used to treat multiple myeloma and other plasma cell neoplasms.

Panobinostat is an HDAC inhibitor used in the treatment of multiple myeloma and other plasma cell neoplasms.

For more information from the National Cancer Institute about multiple myeloma and other plasma cell neoplasms, see the following:

Daratumumab and elotuzumab are monoclonal antibodies used in the treatment of multiple myeloma and other plasma cell neoplasms.

Bortezomib, carfilzomib, and ixazomib are proteasome inhibitors used in the treatment of multiple myeloma and other plasma cell neoplasms.

In 2005, the identification of an activating mutation in JAK2 (the V617F mutation) as a STAT5 - activating and disease - causing genetic alteration in a significant proportion of patients with myeloproliferative neoplasms (MPNs) has emphasized the oncogenic role of the JAK tyrosine kinases in hematologic malignancies.2 — 5 JAK2 is a member of the Janus tyrosine kinase family comprising three other mammalian non-receptor tyrosine kinases (JAK1, JAK3 and TYK2) that associate with cytokine receptors lacking intrinsic kinase activity to mediate cytokine - induced signal transduction and activation of STAT transcription factors.6 All JAKs share a similar protein structure and contain a tyrosine kinase domain at the C - terminus flanked by a catalytically inactive pseudokinase domain with kinase - regulatory activity, by an atypical SH2 domain and by a FERM domain that mediates association to the membrane - proximal region of the cytokine receptors.7, 8 Soon after the discovery of JAK2 V617F, we and others described that activating JAK1 mutations are relatively common in adult patients with T - cell acute lymphoblastic leukemia (ALL) and participate in ALL development allowing for constitutive activation of STAT5.9 — 11 Several STAT5 - activating JAK1 mutations were also reported in AML and breast cancer patients.10

Multiple myeloma and other plasma cell neoplasms (cancers) are diseases in which the body makes too many plasma cells.

In addition to confirming an overall survival advantage and reduction in cardiovascular - related deaths among persons who participate in regular exercise, we also found a reduced rate of deaths from other causes including malignant neoplasms and neurologic disorders.

The most common cause of obstruction is a urethral plug, which consists of mineral crystals (e.g., struvite, calcium oxalate), white blood cells, red blood cells, protein (mucus), and epithelial cells.5 The underlying cause of urethral plugs is unknown; however, plugs have been linked to struvite crystalluria — suggesting that diet may play a role — and idiopathic cystitis.6 Other causes of urethral obstruction include urethral edema and spasm associated with lower urinary tract inflammation and pain.7 Uroliths, neoplasms, and urethral strictures can also lead to urethral obstruction; however, they are reported less frequently than other cauOther causes of urethral obstruction include urethral edema and spasm associated with lower urinary tract inflammation and pain.7 Uroliths, neoplasms, and urethral strictures can also lead to urethral obstruction; however, they are reported less frequently than other cauother causes.5

Malignant or cancerous tumors can originate in the eye or spread from neoplasms (growths) in other areas of the body.

Compared with other types of pituitary neoplasms, these tumors tend to develop in younger dogs.