Sentences with phrase «other nuclear receptors»

The vitamin A — RXR - alpha complex «dimerizes» with these other nuclear receptors, forming a new complex that acts as a transcription factor to turn on gene expression.

Like other nuclear receptors, HNF - 4α has a pocket that binds natural signaling molecules or could be targeted with synthetic drugs.

Not exact matches

The study, «The nuclear transport receptor Importin - 11 is a tumor suppressor that maintains PTEN protein,» which will be published online February 13 in The Journal of Cell Biology, suggests that the loss of Importin - 11 may destabilize PTEN, leading to the development of lung, prostate, and other cancers.

To enable such a system in plants, the re-designed receptors need to be targeted extracellularly and we need to address eukaryotic processes that are not fully understood, such as transmembrane signaling, signal - dependent nuclear translocation, and other signaling complexities.

In addition, others (36) have shown that inhibition of exportin 1, a nuclear export receptor, can lead to accumulation of p70S6K in the nucleus of kidney cells.

Naringenin, a chemical found in grapefruit and in other citrus fruits, activates proteins called nuclear receptors that cause the liver to break down fatty acids, study researchers from Hebrew University of Jerusalem and Massachusetts General Hospital in Boston said in a statement.