Not exact matches
«Most people will have a small
number of effective hours to work, and to the extent those hours can overlap with
other people's, the net
effect will be more impact,» Butterfield says.
«There are a
number of other significant changes to the unfair dismissal regime which will have far - reaching
effects.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and
other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount
of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability
of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction
of generic versions
of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or
other government action that could have the
effect of lowering prices or reducing the
number of insured patients; the possibility
of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels
of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits
of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages
of these products over
other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or
other market conditions; fluctuations in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and
other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
We consider the contributory
effect of mini flash crashes in equity markets, and find that the
number of equity mini flash crashes in the three - minute window between market open and the Treasury Flash Crash was 2.6 times larger than the
number experienced in any
other three - minute window in the prior ten weekdays.
However analyses by law firm Norton Rose Fulbright (NRF) and Fitch Ratings show that a
number of other changes to the tax code will also have significant
effects upon the returns from renewable energy projects, the financing
of these projects and the value
of tax credits.
Actual results may vary materially from those expressed or implied by forward - looking statements based on a
number of factors, including, without limitation: (1) risks related to the consummation
of the Merger, including the risks that (a) the Merger may not be consummated within the anticipated time period, or at all, (b) the parties may fail to obtain shareholder approval
of the Merger Agreement, (c) the parties may fail to secure the termination or expiration
of any waiting period applicable under the HSR Act, (d)
other conditions to the consummation
of the Merger under the Merger Agreement may not be satisfied, (e) all or part
of Arby's financing may not become available, and (f) the significant limitations on remedies contained in the Merger Agreement may limit or entirely prevent BWW from specifically enforcing Arby's obligations under the Merger Agreement or recovering damages for any breach by Arby's; (2) the
effects that any termination
of the Merger Agreement may have on BWW or its business, including the risks that (a) BWW's stock price may decline significantly if the Merger is not completed, (b) the Merger Agreement may be terminated in circumstances requiring BWW to pay Arby's a termination fee
of $ 74 million, or (c) the circumstances
of the termination, including the possible imposition
of a 12 - month tail period during which the termination fee could be payable upon certain subsequent transactions, may have a chilling
effect on alternatives to the Merger; (3) the
effects that the announcement or pendency
of the Merger may have on BWW and its business, including the risks that as a result (a) BWW's business, operating results or stock price may suffer, (b) BWW's current plans and operations may be disrupted, (c) BWW's ability to retain or recruit key employees may be adversely affected, (d) BWW's business relationships (including, customers, franchisees and suppliers) may be adversely affected, or (e) BWW's management's or employees» attention may be diverted from
other important matters; (4) the
effect of limitations that the Merger Agreement places on BWW's ability to operate its business, return capital to shareholders or engage in alternative transactions; (5) the nature, cost and outcome
of pending and future litigation and
other legal proceedings, including any such proceedings related to the Merger and instituted against BWW and
others; (6) the risk that the Merger and related transactions may involve unexpected costs, liabilities or delays; (7)
other economic, business, competitive, legal, regulatory, and / or tax factors; and (8)
other factors described under the heading «Risk Factors» in Part I, Item 1A
of BWW's Annual Report on Form 10 - K for the fiscal year ended December 25, 2016, as updated or supplemented by subsequent reports that BWW has filed or files with the SEC.
While some
of these
effects cancel out
others — beaches opened early this year, while ski resorts prematurely stopped the lifts — a
number of economists say the unusually mild weather was on net an economic plus.
We are monitoring what is happening in the local marketplaces and we are also affiliating with a
number of other organizations to see what kind
of effect (the rules) are going to have on the consumer.
Additionally, the legislation left in place a large
number of legal requirements in the ACA, including the essential benefits package requirements, the prohibition on insurers denying or charging more for coverage for those pre-existing conditions, the limits on «medical loss ratios,» and
other changes that do not have a direct budgetary
effect.
It is also useful to look at the
effect on credit growth
of a
number of other scenarios for loan approvals.
The per - Share
number of Bitcoins exchanged for a purchase or redemption is calculated daily by the Trustee, using the Blended Bitcoin Price, or such
other publicly available price as the Sponsor may deem fairly represents the commercial value
of the Trust's Bitcoins, for the Bitcoins being valued to calculate the Bitcoin amount in respect
of any liabilities for which covering Bitcoins sales have not yet been made, and represents the per - Share
number of Bitcoins held by the Trust, after giving
effect to its liabilities, sales to cover expenses and liabilities and any losses that may have occurred.
While it is
of course true that those who belong to this school are perhaps most vocal in their assertion that in our Lord alone may God be seen at work, and while it is they who denounce the concept
of «general» revelation as a vain fancy
of sub-Christian speculation, a considerable
number of other Christian thinkers take what in
effect is the same position when they make central to their teaching a kind
of uniqueness in the coming and the person
of Christ which effectively removes him from the context
of the total sell - expressive operation
of the Eternal Word.
Creed filmmaker Ryan Coogler, Selma director Ava DuVerney, comedian Hannibal Buress, musicians Stevie Wonder and Janelle Monáe and several
others hosted an event in Flint to raise money for the community that has been
effected by a horrific crisis, in which thousands
of residents — including large
numbers of children — have been exposed to contaminated city water.
A good idea, but please build one and carefully measure the power output, the reliability, the cost, the safety and the
effects on the environment and when you have the
numbers compare them with similar
numbers obtained for
other sources
of energy.
Given, on the
other hand, a
number of legally atomic events and the laws connecting them, it would be possible to deduce their
effects pro tanto without an exhaustive knowledge
of all the coexisting circumstances.
Insistence on biblical science is just a first step toward renewing the church generally: «This will have a ripple
effect as the church wakes up to biblical authority on any
number of other issues.»
It combines a
number of select herbs and spices, potassium, and
other nutrients with demonstrated positive health
effects.
In a small portion
of the population caffeine sensitivity can result in a
number of effects not seen in most
other people.
Such
of these
other manufacturers, including defendant, whose use
of the word «Tabasco» came to the knowledge
of plaintiff and its predecessors, have been warned to the
effect that they have no right to use the word in connection with the sauce, or to use similar packages, and quite a
number of suits for infringement have been filed by plaintiff, most
of which have been terminated by consent decrees.
Arsenal as well as all
other professional football clubs have a
number of sponsorship deals in place, and they have a huge
effect on the finances
of their clubs, with little said on the subjects.
He has complete freedom with the
number 10 role and now he wants to emphasize why he chose Arsenal to the
effect of other world class players joining him.
When Dozier and
other researchers have studied the impact
of ABC on parents (including foster parents) and children, they have found consistently positive
effects according to a
number of indicators.
These include the clarity regarding the
number of blows, the
effects of subclinical impact, the influence
of other noxious influences on the brain, potential underlying genetic susceptibility and specificity
of such histological changes to sport.
Comparing the heart rate or blood sugar levels
of a given
number of people might be beneficial in determining the range in which people maintain good health — and perhaps we can even say that by comparing children's abilities and establishing a range
of «normal,» we can determine which children have difficulties and how to help them — but comparing ourselves with
others, and in particular our children to
other children, can have very damaging
effects.
Research in the United States, Canada, Europe, and
other developed countries, among predominantly middle - class populations, provides strong evidence that human milk feeding decreases the incidence and / or severity
of diarrhea,1 - 5 lower respiratory infection,6 - 9 otitis media,3,10 - 14bacteremia, 15,16 bacterial meningitis, 15,17 botulism, 18 urinary tract infection, 19 and necrotizing enterocolitis.20, 21 There are a
number of studies that show a possible protective
effect of human milk feeding against sudden infant death syndrome,22 - 24insulin - dependent diabetes mellitus,25 - 27 Crohn's disease, 28,29 ulcerative colitis, 29 lymphoma, 30,31 allergic diseases,32 - 34 and
other chronic digestive diseases.35 - 37 Breastfeeding has also been related to possible enhancement
of cognitive development.38, 39
A
number of other small studies support this idea, known as «immunotherapy,» for overcoming various types
of food allergies, but it's still unclear how long the
effects last — it may be that people have to keep consuming the allergen regularly to avoid becoming allergic again — and exposing allergic individuals to their offending allergens can,
of course, be risky.
DR. ROBERT SHULMAN: There's a
number of effects that we know probiotics can have; for example, affecting the immune system, affecting the barrier function
of the intestine, affecting the
other bacteria that live in the intestine.
I'm not quite sure if this embodies the Long Tail
effect, perverts it or turns it on its head, but it's fascinating — as in so many
other public spaces online AND off, most people are good actors, but a small
number of bad ones can really ruin the party.
Opening those massive stores
of statistical data to researchers, watchdogs and that crazy guy who's coding in his basement all night could have serious positive
effects, not the least in bringing in a lot more
number - crunchers to help with analysis and also with relating that data to
other non-governmental sources.
The net
effect of this restructuring was to cut approximately 20,000 white non-Hispanics out
of the district while capturing about the same
number of Hispanics on the
other side.
These
effects largely cancelled each
other out, meaning that the final total
of women was only one shorter than the
number predicted by the Electoral Reform Society, who forecast 192 women MPs.
Those
numbers don't include the ripple
effect as people forward it on to colleagues and
others, and they're also destined to go up as the promotional campaign chugs along (press release hits the wires tomorrow, for instance, and the ebook should have a mention in the next issue
of Campaigns & Elections magazine).
Gennaro and
other opponents
of fracking in New York have raised the issue's visibility in part by pointing to the disastrous
effects the practice has had in a
number of Western states that have allowed it, and in Pennsylvania, which shares the same source
of gas as New York State, the Marcellus Shale formation, which runs from the Southern Tier to West Virginia, and west to part
of Ohio.
Under the Kavanagh / Squadron bill, the factors applicable to all license applications would include the
number, type, and proximity
of other licenses in the area; whether the applicant has necessary permits; the potential
effect of the license on traffic and parking; noise levels; any history
of liquor violations or criminal activity at the premises; any history
of building and fire violations at facilities operated or owned by the applicant; and any formal communications about the application from the municipality or community board.
A statement signed by the Head
of Public Relations and Communications said, «With
effect from 1st June, 2016, GWCL meter readers will be capturing customer consumption data with a hand - held android device equipped with a software, which already has customers» data comprising the following: customer name, customer phone
number, customer's last captured consumption data, customer's geographical location and
other relevant information».
Again we can infer that Osborne has used his opportunity to good
effect, getting his side
of the story across on a
number of Tory controversies while remaining opaque on
others.
«Employment
numbers were up toward the end
of 2014, we felt that hiring was going to be up for 2015, again, we'll see what'll happen in the second half
of the year, but that's important because we estimate that for every job that's created on Wall Street, and in financial services, two
other jobs are created in
other parts
of the city's economy, one
other job outside
of New York City but within New York State, so there is that multiplier
effect.»
The FDA in the Ashanti region says it has undertaken a
number of activities to reduce the harmful
effects of abusing Tramadol and continues to partner
other state agencies to curb the illegal distribution and sale
of the drug.
The authors point out that the literature has a
number of methodological limitations, such as measurement and selection bias, and a restricted focus, in which the
effects of a limited
number of alcohol policies are considered without accounting for
other alcohol policies.
This association held even after the researchers accounted for
other potential factors, including total population,
number of law enforcement employees, median age, gender distribution, race distribution, poverty rate, unemployment rate, unobserved heterogeneity among cities (e.g., city area, legal system), and unobserved time - varying
effects (e.g., macroeconomic conditions).
Lithium is considered a highly effective treatment for bipolar disorder and
other mood disorders, but it still works in only a fraction
of patients and has a
number of side
effects.
The challenge,
of course, is to somehow meld a bewildering array
of data sets: all sorts
of historic and current medical records about each person and all sorts
of scientific reports on a
number of drugs, drug tests, potential side
effects and outcomes for
other patients.
The review found that clonidine given at 4 micrograms / kg had a low
number of side
effects compared with
other pain medications.
However, all
other outcomes failed to show an
effect of baclofen: baclofen did not increase abstinent days or decrease
number of heavy drinking days during treatment, neither did it reduce rates
of alcohol craving, anxiety or depression.
The newly detected quasiparticles are interesting for a
number of reasons: «Even if Weyl fermions were initially found in
other materials, it is much easier to control the
effect in our strongly correlated materials,» says Silke Bühler - Paschen.
At some stages
of the epidemic the
number of reported cases had an
effect on news coverage, while at
others the news coverage had an
effect on the
number of cases.
The elimination
of this host factor via the deletion
of the FREP1 gene had
other effects besides reducing the
number of mosquitoes infected with malaria.
«The key aspect
of our study which gives us considerable confidence in our findings is that we were able to show that river flows and waterbird
numbers were closely related, despite a range
of other factors we examined, including the
effect of duck hunting,» says study co-author and UNSW research fellow Dr Gilad Bino.
Professor Thangaratinam added: «Often with interventions like these, certain groups benefit more than
others, but we've shown that diet and physical activity has a beneficial
effect across all groups, irrespective
of your body mass index (BMI), age or ethnicity; so these interventions have the potential to benefit a huge
number of people.»
There isn't any
other toxicant that we know
of that even comes close to arsenic in terms
of the
number of health
effects at the doses we're seeing and the
numbers of people worldwide who are potentially exposed.»