The history of addiction involving laudanum and
other opioid painkillers — America's first epidemic of opioid addiction occurred in the second half of the nineteenth century — may have worried many physicians considering this new crop of drugs.
Since fentanyl is so much more potent than
other opioid painkillers, drug traffickers only need to pack their drugs with small amounts of it to provide users a powerful punch.
Not exact matches
Taking dangerous quantities of the otherwise safe loperamide is one strategy being used by people addicted to
opioid painkillers and
other drugs since it can increase
opioid absorption in the gut; the FDA says it is now working with loperamide manufacturers to change its packaging so that it comes with fewer doses and is thus harder to abuse.
A new government - funded study suggests that addictive
opioid painkillers may not be better than
other, non-
opioid kinds of drugs for treating chronic back pain and arthritis.
The investigators told the AP they discovered two dozen pills in an Aleve bottle in Prince's home that had been labeled «Watson 385,» a stamp used to ID pills that contain a mix of two
other pain - relieving medications: hydrocodone (another powerful
opioid painkiller) and acetaminophen (the active ingredient in Tylenol).
In a statement released Friday, coroner Jonathan Lucas said that Petty's system showed signs of several
opioid painkillers, including fentanyl and oxycodone, in addition to the
other drugs.
FBI agents arrested former Insys Therapeutics (insy) CEO Michael Babich and five
other former company executives on Thursday for allegedly bribing doctors to prescribe an extremely addictive
opioid painkiller to patients who didn't need it.
New York city is the latest U.S. city to bring a lawsuit against Purdue Pharmaceutical and
other companies involved in manufacturing and distributing prescription
painkillers, known as
opioids.
He sees similarities between the push to legalize marijuana and what he called the «right to pain treatment» movement of the 1990s that paved the way for more liberal prescribing of hydrocodone and
other highly addictive
opioid prescription
painkillers.
The researchers hope their findings could help
other large health systems use their own electronic medical systems as part of a larger initiative to address a key aspect of the nation's epidemic of
painkiller overdoses and
opioid addiction.
«American effort reduced risky
opioid prescriptions for veterans, study finds: Reductions in highest doses through computer «dashboard» and prioritizing
painkiller safety suggests
other large health systems could do the same.»
The Bradfords haven't yet analyzed how many of those doses were
opioid drugs versus
other painkillers, but David Bradford suspects it's a large chunk.
They injected some subjects with a powerful
opioid painkiller and
others with a placebo and had them rate their pain.
Other Mayo studies discussed at the conference chronicled a significant increase in gout; examined rare intestinal microbes in rheumatoid arthritis patients; and discovered that people with rheumatoid arthritis use
opioid painkillers at a higher rate than the general public, but that it isn't related to disease severity.
Scientists are searching for a different kind of shot to prevent such tragedies: a vaccine to counter addiction to heroin and
other opioids, such as the prescription
painkiller fentanyl and similar knockoff drugs.
There are also
other public health implications: Antibiotics in too low doses may not help a patient fight an infection, but they can be sufficient to induce resistance in bacteria, and counterfeit
painkillers containing fentanyl, a powerful
opioid, are a major contributor to the
opioid crisis, according to the DEA.
These people have difficult, infrequent bowel movements — no more than two per week — not due to
other medical conditions or medicines they may be taking, such as
opioid painkillers.