Sentences with phrase «other populations of patients»

The combination should be studied in other populations of patients, Adelson added, including those who are newly diagnosed with metastatic breast cancer and those who have already progressed on fulvestrant.

Not exact matches

«While we are disappointed CheckMate - 026 did not meet its primary endpoint in this broad patient population, we remain committed to improving patient outcomes through our comprehensive development program, including the ongoing Phase III CheckMate - 227 study exploring the potential of the combination of Opdivo plus [our other cancer immunotherapy] Yervoy for PD - L1 positive patients, and Opdivo plus Yervoy, or Opdivo plus chemotherapy in PD - L1 negative patients,» he added.

Although the growing share of the elderly population means that demand for this segment of telehealth will grow, the increasing capabilities of remote patient monitoring devices, like fitness trackers and smartwatches, and mHealth apps will likely cause many of these designated devices to fold into the other segments of telehealth.

To cite just one example: Executives at Trinity Health, which operates 93 hospitals, have their pay tied to the system's overall effectiveness in keeping patients out of the hospital, lowering smoking and obesity rates, and other population health metrics.

Once she can start aggregating data from her patients with data from other doctors who are using the app, she will have a huge number of data points that she can use to track everything from the efficacy of the surgery in certain patient populations, to which doctors might get the best outcomes.

Both of these types of organizations, among others, tend to have diverse populations, it would be nothing short of doctrinaire to impose a particular religious dogma on the medical care of everyone who is a patient, a student or an employee.

ONS Harrison will serve the practice's current patient population and other residents of Westchester County and surrounding New York communities.

Addressing previous concerns about Summit Park's population, Carey also said that in the event of a complete closure, its patient care responsibilities would be gradually transferred to other providers over the course of several years.

If other surgeons in other settings with other patient populations have similar results with the device, we can apply to the FDA for a 510 (k) clearance and begin to bring the product into more widespread use,» said Michael Harrison, MD, FACS, professor emeritus of surgery at UCSF.

«These exciting results indicate that there is a new standard of care option for a population of head and neck cancer patients with no other treatment options,» said the trial's international co-chair Robert Ferris, M.D., Ph.D., UPMC Endowed Professor, and chief of the Division of Head and Neck Surgery and co-leader of the Cancer Immunology Program at UPCI.

By using these and other high - tech tools, the researchers homed in on a unique population of T - cells that are highly prevalent in the joints of rheumatoid arthritis patients.

«While Massachusetts safety - net hospitals (many of which are minority - serving) received large cuts in payments with the idea that other hospitals would assume the care of previously uninsured patients, this study demonstrates the importance of securing the future of safety - net and minority - serving hospitals through policy - based interventions to assure the continued care of vulnerable and underserved patient populations.»

Vemurafenib joins other multi-targeted kinase inhibitors (MKIs)(sorafenib, lenvatinib) shown to be effective in this patient population; in spite of responses to these drugs, the responses are temporary and additional treatment options are needed.

If so, says Grover Bagby, a hematologist who directs the Oregon Cancer Center at the Oregon Health Sciences University in Portland, further work to decipher the protein's exact function could shed light on how to treat a much larger population of patients with leukemia, certain other forms of cancer, and aplastic anemia.

The research team with international collaborators analysed more than 100 patient samples from ovarian and other cancer types to discover a distinct population of cells found in some tumours.

Future research should look at data from state prescription drug monitoring programs and data on other substance use to get a more comprehensive view of how patients are using opioids,» said Karen E Lasser, MD, MPH, a general internist at BMC with expertise in improving the quality of care for underserved patient populations, who served as co-principal investigator of the study.

• 25.3 % of COPD patients from other populations had heart failure compared to 11.3 % in their counterparts who did not have COPD.

Moreover, the demography of the Ashkenazi population, the largest isolated population in the U.S., enables large - scale recruitment of study patients and hence more genetic discoveries than in other well - known isolated populations like the Amish and Hutterites locally, or the Icelanders overseas.

Patient recruitment is an enormous problem in many medical studies, and researchers often end up paying for the participation of students, poor people, drug abusers, the homeless, illegal immigrants, and others who may not adequately represent the population in terms of health or lifestyle.

Treatment and recovery of the elderly population is even more challenging for physicians and other caregivers because these patients are more likely to have other health issues that can complicate their recovery and rehabilitation.

Domestic violence from family members (other than partners) made up 63 % of total domestic violence cases against psychiatric patients compared with 35 % of the general population.

As the proliferation of smartphones and other mobile devices continues, healthcare professionals — and patients — see promising vehicles for the delivery of health - related interventions to large segments of the population.

The researchers also hope that the algorithm will enable other researchers to study the pathway, possibly leading to a better understanding of its role in human cognition and in patient populations.

Strong results from the other arm of CoreValve's U.S. Pivotal Trial with patients at extreme risk for standard aortic valve - replacement surgery were reported in October and led to Food and Drug Administration approval for the device in this population.

Traynor's team examined hundreds of patients and control subjects in Finland, where ALS is nearly twice as common as in other Caucasian populations.

«We need to study a broader patient population to not only validate these findings but also determine other factors, such as inflammatory cytokines, that may contribute to the development of fatty liver in the IBD population.»

Recent innovations in health - care delivery emphasize «population health management» — that is, trying to promote population health by making sure people get preventive care, increasing monitoring of patients with chronic conditions, and increasing follow - up with patients in poor health, among other methods.

This speaks to the fact that patients were representative of the typical population being treated in current practice and unlike many other studies, high risk patients were not excluded from participating in the study.

But patients who had neurological infections had a higher risk of dying of some other diseases than the general population.

We leverage our cutting - edge platforms to produce product candidates and utilize distinct therapeutic approaches that, we believe, address the shortcomings of existing therapies and have the potential to treat a broad patient population either as individual therapies or in combination with other mechanisms of action.

In addition to her expert skill as a clinician, Dr. Frontera also has many research interests including identifying biomarkers and predictors of early brain injury and vasospasm / delayed cerebral ischemia after subarachnoid hemorrhage and their impact on outcome; determining the efficacy of therapeutic strategies and developing guidelines for the management of patients with intracranial hemorrhage; evaluating the cost, length of stay, quality of life, functional and cognitive outcomes in a broader population of intracranial hemorrhage patients; developing guidelines for the integration of palliative care into the intensive care unit setting; and evaluating the relationship of Zika virus infection, Guillain - Barre, and other neurologic disorders.

«This analysis of a large population of patients across a broad scope of tumor types suggests that avelumab was associated with an incidence of immune - related adverse events that is consistent with that of other immune checkpoint inhibitors.»

Patients with hematological malignancies are at a particularly higher risk of developing severe infections when compared to other patients with solid tumors and the population in Patients with hematological malignancies are at a particularly higher risk of developing severe infections when compared to other patients with solid tumors and the population in patients with solid tumors and the population in general.

Our two primary product candidates, CMB305 and G100, utilize distinct immuno - oncology approaches that, we believe, address the shortcomings of existing therapies and have the potential to treat a broad patient population either as individual therapies or in combination with other mechanisms of action.

We also performed subgroup meta - analyses by type of prevention (primary v secondary: in this study, trials involving healthy populations or patients with any specific disease except for cardiovascular disease were classified as primary prevention trials, and trials involving patients with cardiovascular disease were classified as secondary prevention trials), type of supplement by quality and dose (each supplement, vitamins only, antioxidants only, or antioxidants excluding vitamins), type of outcome (cardiovascular death, angina, fatal or non-fatal myocardial infarction, stroke, or transient ischaemic attack), type of outcome in each supplement, type of study design (randomised, double blind, placebo controlled trial v open label, randomised controlled trial), methodological quality (high v low), duration of treatment (< 5 years v ≥ 5 years), funding source (pharmaceutical industry v independent organisation), provider of supplements (pharmaceutical industry v not pharmaceutical industry), type of control (placebo v no placebo), number of participants (≥ 10000 v < 10000), and supplements given singly or in combination with other vitamin or antioxidant supplements by quality.

Label the FDA approved label is the official description of a drug product which includes indication (what the drug is used for); who should take it; adverse events (side effects); instructions for uses in pregnancy, children, and other populations; and safety information for the patient.

The current recommendation is based on unique conditions associated with the current pandemic, including low levels of population immunity to 2009 H1N1, the potential for health - care personnel to be exposed to H1N1 patients, and other factors, Dimond says.

It's very interesting to us that many patient populations (from psychiatric conditions like depression to other populations like traumatic brain injury and neurogeneration) show issues in similar domains dependent on this cognitive control, so we're exploring the potential of the technology in various populations to see where we have the most impact on patients.

The population has grown over 22 % since 2000, and a disproportionate amount of that has been in the form of new residents flocking to Colorado due to two significant legal changes in recent years which make the state more attractive for same sex couples and patients with chronic pain and certain other ailments.

Other major contributing factors are the infrequency of preventive measures in the country and the high number of undiagnosed and subclinical patients, leading to a reservoir of hosts in the general canine population.

Misdiagnosis occurs most frequently in young patients because they are rare in this population and in the elderly because the symptoms of stroke are easily mistaken for other age related diseases.

Watertown, MA About Blog Athenahealth is a leading provider of network - enabled services for electronic health records (EHR), revenue cycle management and medical billing, patient engagement, care coordination, and population health management, as well as Epocrates and other point - of - care mobile apps.

Graduate Practical Nurse — Duties & Responsibilities Accumulate 678 clinical hours in medical / surgical, cardio vascular, neurology, obstetrics, gynecology, pediatrics, pediatric oncology, and outpatient care at the Veteran's Administration Obtain and maintain federal clearance to work with VA staff and patients Assist more than 200 RN's, Charge RN's, CNA's, and physicians Perform intake, preoperative clearance, history and physical, EKGs, lab tests, discharge, and follow - up Assess, diagnose, and treat sprains, strains, lacerations, and other physical injuries Responsible for IV line insertion, blood product administration, and medication Determine severity of patient condition and promptly refer to specialists when appropriate Develop and administer disease management plan ensuring high quality, comprehensive care Provide acute episodic and chronic care to adult and pediatric populations Facilitate case management, consultation, and interdisciplinary patient care Educate patients in healthy diets, exercise, smoking cessation, and overall positive lifestyles Maintain working knowledge of current medical technology, procedures, and standards of care Proven ability to remain calm and levelheaded in high pressure, emergency care situations Perform administrative functions including phones, data entry, and other tasks as needed Perform all duties in a positive, professional, and courteous manner

Licensed Practical Nurse — Duties & Responsibilities Provide exceptional patient care and medical team support across multiple medical specialties Experienced in orthopedics, rehabilitation, transitional care, cardiology, med surgical, oncology, pediatrics, urology, pulmonary, geriatrics, and neurology Perform preoperative clearance, history and physical, EKGs, lab tests, discharge, and follow - up Assess, diagnose, and treat sprains, strains, lacerations, and other physical injuries Responsible for IV line insertion, blood product administration, medication, feeding tubes, and PICC line draws Determine severity of patient condition and promptly refer to specialists when appropriate Develop and administer disease management plan ensuring high quality, comprehensive care Provide acute episodic and chronic care to adult and geriatric populations with complex medical conditions Facilitate case management, consultation, and interdisciplinary patient care Educate patients in healthy diets, exercise, smoking cessation, and overall positive lifestyles Maintain working knowledge of current medical technology, procedures, and standards of care Proven ability to remain calm and levelheaded in high pressure, emergency care situations Perform all duties in a positive, professional, and courteous manner

Existing interventions among Asian populations focus mainly on imparting practical skills to caregivers of patients with cancer requiring palliative care, through home - based care or home visits from nurses, 21 — 23 with an emphasis on coping with end - of - life issues and bereavement.24, 25 However, interventions for caregivers of non-palliative care recipients tend to be delivered via the phone26 or over the internet, 27 while others work with couple dyads, where one spouse provides care for the other who has cancer.28

The relationship between depressive symptoms and step count has only been assessed in specific populations with small sample sizes, such as low - socioeconomic status Latino immigrants, 16 elderly Japanese people17 or patients with chronic conditions such as heart failure18 19 or chronic obstructive pulmonary disease.20 21 Studies yield contradictory results, with some observing no association between depressive symptoms and daily step count, 19 21 while others report a negative correlation.16 — 18 20 In one cross-sectional sample of healthy older adults, an inverse association between depressive symptoms (using the Goldberg Depression Scale - 15) and accelerometer measured daily step count disappeared after controlling for general health and disability.22 While a systematic review suggests reduced levels of objectively measured PA in patients with depression, 23 it is not known whether this association is present in those at high risk of CVD and taken into account important confounding such as gender and age.

Factor structure, internal consistency, construct, and criterion validity were investigated in three samples of participants (315 from the general population, 106 OCD patients and 31 with other anxiety disorders [OADs]-RRB-.

Several studies have reported that early trauma, and especially childhood sexual abuse, specifically increases the risk of later hallucinations in both schizophrenia and bipolar patients.69 — 73 On the other hand, insecure attachment appears to be specifically associated with paranoia and not hallucinations.45, 46 Evidence that discrimination or victimization plays a specific role in the development of paranoid beliefs has emerged from a population survey in the United States and Mexico, 39 from a prospective population - based study in Holland, 32 and from patients» retrospective reports of their experiences of intrusive74, 75 and threatening76 life events (as noted above, this effect may contribute to the elevated rates of psychosis in immigrant populations).