Sentences with phrase «other receptors»

The molecule can influence signals sent by a number of other receptors in the brain, many involved in pain and inflammation.

This new tool made it possible to gain a more precise understanding of this receptor's effects without the noise of other receptors.

Several antibody drugs have been developed to target other receptors found on cancer - cell surfaces.

Histamine can also affect other receptors of the cell surface than the H1 receptor,» Professor Harvima explains.

The team is also investigating other receptors on melanocytes that might influence melanin production.

For example, the sugar in flavored malt beverages will presumably reduce or eliminate the bitterness of ethanol while the addition of hops to beer will add bitterness that may be perceived through other receptors.

But skin deformations also radiate away from this area, down the fingers, and throughout the rest of the hand, activating many other receptors in the process.

An opioid might activate the orphan receptor, but it might also activate other receptors that it interacts with.

Because type III cells appear to integrate information from other receptor cells (Tomchik et al., 2007) and use the 5 - HT3 system to transmit information, these previous nerve recording studies may have inhibited transmission of integrated cross-modal information from type III cells, leading to the appearance of strict labeled - line, modality - specific transmission of information.

The two receptors are homologous with each other, rhodopsin, and other receptors coupled to guanine nucleotide regulatory proteins and they contain seven hydrophobic domains, which may represent transmembrane spanning segments.

Investigators linked the ability of regulatory T cells to dampen the Th2 response in part to the ability of LKB1 to restrain expression of the cell surface receptor PD - 1 and possibly other receptors.

The problem is that some of the molecules coming to rest on top of the precursor layer are so large that they block other receptor points.

Both have their primary activity at the serotonin 1A receptor, though other receptor activities differ.

It is possible that the 5 - HT3 receptor that we demonstrate in the ganglion cell somata is not transported to the distal processes that innervate taste buds but other receptors present in cell bodies of taste ganglia are, including P2X receptors (Bo et al., 1999) and GLP - 1 receptors (Shin et al., 2008).

Highly respected throughout the world, Dr. Mark Brownfield spent decades at the University of Wisconsin - Madison producing highly effective serotonin and other receptor antibodies.

Like other receptors, Tsr spans the cell membrane, communicating to proteins inside the cell in order to respond to threats or opportunities in the environment.

They can also be taken back up by the presynaptic cell via other receptors (orange) for re-use.

«Alcohol clearly affects other receptors too,» admits Harris, of the University of Colorado Health Sciences Center.

In addition, at least some Eph receptors can also signal through non-canonical mechanisms that are independent of ligand binding and kinase activity, for example through interplay with other receptor tyrosine kinase families and with serine / threonine kinases.

This means the drugs were suppressing pain while leaving other receptors unaffected, drastically reducing the risk for addiction.

Although 5HT (2A) receptors mediate contractions of normal arteries to serotonin (5HT), in some cardiovascular diseases, other receptor subtypes contribute to the marked increase in serotonin

The idea was to have a more targeted approach to only cover the receptors that are transmitting the pain and not hitting other receptors that have to do with housekeeping effects, like the integrity of the intestinal lining that NSAIDs attack, like kidney function and liver function, so to have a drug that has a better safety profile, especially in older patients.»

But it may be possible to target other receptors on the interneurons that influence the release of acetylcholine, Bamford says.

But there are others such as adiponectin signaling, nutrient signaling through other receptors, and a number of metabolites that are involved in the metabolic signaling cascades.

These results suggest that the optical biosensor system could be used to screen for compounds that block EGFR and many other receptors, potentially speeding up the hunt for drugs against several diseases.

(B) Eph receptors can potentiate the oncogenic effects of other receptors.

To see if any other receptors existed, Rodriguez's team took tissue from the vomeronasal organ — a pheromone - detecting sense organ found in the nasal cavity of mice, and some other mammals — and searched for genes expressing other possible smell receptors.

The study will enroll 150 patients diagnosed with schizophrenia or bipolar disorder and 50 healthy people between the ages of 18 and 35 who are willing to undergo a spinal tap to collect a small amount of their cerebral spinal fluid, which will be screened for the presence of antibodies attacking NMDA and other receptors.

However, Wills - Karp expects that other receptors on airway cells recognize these ubiquitous plant - derived allergens and she hopes to find them in future research.

The researchers continue to study the effects of treatment in both mice and dogs, improve the photoswitch, and develop ways of attaching the photoswitch to other receptors, including some that could amplify the signal and allow perception of fainter light, as occurs normally in rods and cones.

Their venom peptides hit a wide variety of pain targets, including sodium channels, calcium channels and other receptors.

Because a particular apoE variant, called apoE4, had previously been shown to be a risk factor for late - onset Alzheimer's, Tanzi and his colleagues reasoned that the mutant form of this other receptor - binding protein, a2M, might be as well.

But unlike any other receptor in the body, it has more than one region that can be activated by different molecules.

Could THC be acting on the other receptor in the endocannabinoid system, CB2?

Through computer analysis they were able to modify the chemical makeup of the compounds and find the precise formulation for creating the strongest bond between the compound and the kappa opioid receptor without affecting any other receptors in the cell.

«There could be 20 other receptors that we haven't looked at.

Beta - receptors are the other receptors involved in the regulation of Lipolysis.