Sentences with phrase «other related genes»
In addition to Otop1, there are two other related genes in vertebrates (Otop2 and Otop3), and this gene family is represented in the fruit fly Drosophila melanogaster.
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The other related genes, DFR - A and DFR - C, were examined and no mutations were found, confirming the high specificity of the CRISPR / Cas9 system.
Not exact matches
These new entrants would need to get a licensing agreement from Myriad for anything they discovered related to the BRCA genes, which would effectively shut down future work by anyone other than Myriad in this area.
Habit then uses blood samples and DNA from a cheek swab to glean details on glucose levels and obesity - related genes, among other factors that could affect metabolism.
Although she doesn't have a BRCA gene, Kati's cancer seems very similar to cancer that her maternal grandmother had and due to the way it has responded to treatment it is most likely related to other genetic factors.
My tgf - beta gene was part of a big family of genes, and I began making phylogenetic trees in order to better understand how it was related to the other family members.
Lu's lab is now using this approach to screen for genes related to other disorders, and the researchers have already identified some genes that appear to protect against certain effects of aging.
Mutations in the genes that defend the body against cancer - related viruses and other infections may play a larger role in breast cancer than previously thought, according to a study at the University of Illinois at Chicago.
When the team induced expression of the corresponding gene in the leaves of two other plant species (one closely related to S. lycopersicum and the other more distantly related), both plants reacted to presence of the C. reflexa peptide with increased production of ethylene, and exhibited increased resistance to C. reflexa infestation.
Other researchers have identified dozens of genes, all related to the growth and spread of cancer, that become over - or undermethylated when the disease gets under way.
For them, the discovery of how an individual becomes gay is likely to shed light on how sexuality - related genes build brains, how people of any persuasion are attracted to each other, and perhaps even how homosexuality evolved.
However, other institutions and companies have continued to file patent applications on ESTs and related genes; at present there are applications covering more than 1 million ESTs on file in the PTO.
Others have found that boys are more vulnerable than girls to the long - term impact of maltreatment in childhood, and the risk of such boys becoming antisocial in later life seems to be related to a gene on the X chromosome, although not one that is imprinted.
One encodes retinoid - related orphan receptor alpha (RORα), a transcription factor that itself regulates multiple other genes.
The second gene, TNFRSF6B, encodes a receptor related to those that bind tumor necrosis factor (TNF)-- a key chemical signal for triggering inflammation in IBD as well as in patients with other autoimmune disorders such as rheumatoid arthritis and psoriasis.
«In the current study, we analyzed dozens of variants of those genes and other genes frequently associated with obesity risk and saw that, while total fat intake was related to higher BMI, people who were genetically predisposed to obesity and ate the most saturated fat had the highest BMIs.»
At first, it was difficult to imagine how pathogens can acquire genes from Actinobacteria, because they are so different and not at all related with each other.
This analysis produced networks that mapped out how alpha - synuclein is related to other Parkinson's genes through well - defined molecular pathways.
«The other major part of the story is that in mycorrhizal lineages there is a huge turnover in genes that are upregulated in the symbiosis - many of these have no homologs in even closely related species, suggesting that the evolution of the symbiosis is associated with massive genetic innovation.»
They also ruled out other possibilities, including the gene spontaneously mutating back to the normal form, the existence of more than two copies of the hothead gene, or closely related DNA sequences providing a template for repairs.
SIX3 and a related gene, SIX2, with a similar pattern of expression in human beta cells, encode proteins known as transcription factors that control the expression of many other genes in the cell.
Even distantly related bacteria can swap genes with one another using a variety of techniques, from direct cell - to - cell transfer, called conjugation, to transformation, in which a bacterium releases snippets of DNA that other bacteria pick up and use.
And 40 genes involved in these nine schizophrenia - related pathways also differed much more between chimps and humans than genes associated with the other 12.
The new study examined the entire set of active genes, or the transcriptome, of 24 conifers and other seed plants and three distantly related plants.
Banfi says that the related genes expressed in a variety of tissues suggest that reactive oxygen species will turn up in other surprising roles.
«Now that we know how calcification happens and what the key nodes are, we know what genes to look for that might be mutated in other related forms of cardiovascular disease.»
The discovery of the gene for Native American myopathy, however, may help develop drugs to treat the myopathy, as well as other related muscle diseases.
Going forward, Malhi plans to investigate the immune - related genes of other indigenous communities.
They did, however, find copies of genes related to CDR1, CDR2, and few others that encode other transporters associated with drug resistance — although the way they function in C. krusei is unknown.
Together with research into other immune - related genes in diseases such as Alzheimer's, the idea that immune processes are involved in some psychiatric phenotypes is looking ever more solid.
If Hamilton's hypothesis was correct, «successful» virtual robots were likely to be those that were closely related and shared food with each other; that would help to ensure that at least one of them — and some of the genes of both — would make it to the next round.
The other team, led by medical psychologist Julie Williams of Cardiff University in Wales, noted the same CLU gene and identified another Alzheimer's - related gene, PICALM.
If the genes related to color and the genes involved in this aspect of vision sit near each other on the genome, they are more likely to be inherited together.
Other animals possess their own versions of FOXP2, suggesting that it might be possible to determine which evolutionary changes to the gene's DNA sequence are most closely related to our ability to talk.
«If you identified genes that were completely random and not related to each other, that would be suspicious,» says Iossifov.
«And we believe there will be many more discoveries related to other orphan genes in the future.»
HDNetDB allows users to obtain, visualise and prioritise molecular interaction networks using Huntington's disease - related gene expression and other types of data obtained from human samples and other sources.
Earlier versions of these «base editors,» which target typos related to the other half of disease - causing genetic spelling errors, have already been used to alter genes in plants, fish, mice and even human embryos.
By comparing the armadillo gene to other closely related mammals, a team of scientists has now identified several cone - related genes in the armadillo genome that became nonfunctional millions of years ago, they report today at the Society for Neuroscience conference in San Diego, California.
Heat messes with the proteins made from JARID2 and JMJD3, which in turn mess with the proteins made by other sex - related genes, the researchers propose.
In the new study, the researchers discovered that during the second trimester of human brain development, oRG cells express genes related to a fundamental signaling pathway called mTOR, defects in which have previously been implicated in autism and several other psychiatric disorders.
«GECCO aims to continue to discover additional colorectal cancer - related variants by investigating how genetic variants are modified by other environmental and lifestyle risk factors, including biomarkers as well as how they influence patient treatment response and survival,» Peters said, emphasizing how much further research is required to uncover the specific mechanisms by which genes modulate the intake of certain foods on colorectal cancer risk.
Are there tests that pick up whether a person has other fitness - related genes?
Approximately 50 percent of the female patients exhibited abnormally higher levels of XIST and other genes related to the X chromosome.
Two other, very closely related genes (DFR - A and DRF - C) sit side - by - side, next to DFR - B.
... The FOXP2 gene has been around for a very long time, found in similar form in distantly related vertebrate species, and it may be important not only for brain development and function but also in other tissues.»
The Amur tiger genome was predicted to contain 20,226 protein - coding genes and 2,935 non-coding RNAs, and was enriched in olfactory receptor sensitivity, amino - acid transport, and metabolic - related genes, among others.
Unlike some other common vision disorders, such as age - related macular degneration, color blindness is a heritable disorder caused by a single gene that is defective or absent.
Based on studies of other genes related to FOXP2, the authors suggest that the loss of functioning protein from one copy of this gene might disrupt the proper growth of key speech and language structures in the brain.
Still, Dudley feels that evolutionary genetic analysis can help identify the most relevant genes and pathological mechanisms at play in schizophrenia and possibly other mental illnesses that preferentially affect humans — that is, neurodevelopmental disorders related to higher cognition and GABA activity, including autism and attention - deficit / hyperactivity disorder.