Sentences with phrase «other resistance genes»

A three - phase experiment was conducted on a doubled - haploid population derived from the cross RL4452 / AC Domain to determine if the resistance of a recently discovered gene (Lr2BS) worked with other resistance genes to synergistically enhance resistance to leaf rust.
A plasmid in the E. coli carried the gene for extended spectrum cephalosporin resistance, as well as four other resistance genes.
What is so encouraging about the first successful unpicking of a wheat gene that confers resistance to a devastating fungal disease is the promise it holds for deciphering other resistance genes, en route to a natural barrier to infection, at a time when the fungus has already developed tolerance to most types of fungicides.
«We're also looking at as many genes as possible in the wild banana and screening them to identify other resistance genes, not only for resistance to TR4 but to other diseases.»

Not exact matches

I won't reveal yet who my favorites are, but I will say that these young scientist - founders came up with very creative solutions for preventing infections in some common surgeries, tackling resistance in targeted antibody drugs, improving gene vectors for cell therapies, helping the vision - impaired «see» faces and better read their environments, imaging hard - to - see spots in the lungs and other organs, improving genetic risk analysis, and expediting the logistical operations of hospitals.
Scientists could search within them for resistance genes and other desirable traits to use in engineering and breeding programs.
Researchers now have the tools to identify resistance genes in wild bananas or other plant species.
The bacteria behind gonorrhoea readily acquire genes for resisting drugs and so from 2012, UK patients were given two antibiotics at once — azithromycin pills plus a ceftriaxone injection — so if bacteria acquired resistance to one, they would be killed by the other.
One of the newest banes of U.S. medical centers, a supervirulent and multidrug - resistant strain of Acinetobacter baumannii, likewise appears to have picked up most of its resistance in gene swaps with other species.
The scientists also generated a panel of (reconstructed) ancestral and existing TRIM5 genes (19 total), expressed them in cultured cell lines, and exposed the cells to 16 different retroviruses (lentiviruses and others) to see which TRIM5 versions conferred resistance to which viruses.
When the team induced expression of the corresponding gene in the leaves of two other plant species (one closely related to S. lycopersicum and the other more distantly related), both plants reacted to presence of the C. reflexa peptide with increased production of ethylene, and exhibited increased resistance to C. reflexa infestation.
At this stage, the bacteriophage infected other Salmonella cells, possibly also spreading novel virulence or resistance genes, the authors say.
The activity of four transcription factors — proteins that regulate the expression of other genes — appears to distinguish the small proportion of glioblastoma cells responsible for the aggressiveness and treatment resistance of the deadly brain tumor.
So even if you start off [with] say, a resistant type of staph infection, that line of staph organisms not only, will they be more resistant, but they may pass some of the genes for that resistance off to completely other unrelated types of bacteria.
Genetic factors can contribute to the degree of longevity in at least two important ways: An individual may inherit certain genetic variations that predispose him or her to disease that decreases longevity; other gene variants may confer disease resistance, thereby increasing it.
The gene for colistin resistance can be easily spread to other bacteria, making it likely that colistin resistance will become widespread in the future.»
The researchers suspected those hyperactive genes might be behind the resistance — playing off each other to create a smaller network within the larger tuberculosis response network.
Although many different malaria resistance loci have been postulated over the years, this is one of very few that have stood up to stringent testing in a large multi-centre study; the others include the genes for sickle cell and the O blood group.
The team cut and pasted a bovine gene for NRAMP1, a protein linked to resistance against TB and other bacterial infections, into fetal dairy cow genomes.
The other glyphosate - resistance mechanism involves the same gene.
Still, the qualities that make it easier for certain bacteria to pick up the resistance gene, and other genes that enhance that one's performance, are unclear, the researchers report in the 1 March issue of Lancet Infectious Diseases.
The researchers also found genes in these isolates that confer resistance to numerous other antibiotics, as well as genes associated with decreased susceptibility to disinfectants.
Finally, the researchers found that the vancomycin - resistant enterococci (VRE) bacteria found in the untreated wastewater contains a gene capable of transferring vancomycin resistance to other strains of bacteria.
By comparing differences in the gene that confers antibiotic resistance, as well as other pieces of DNA, the team determined that 70 % of their samples included just five bacterial strains.
«Nevertheless, this gene will be useful in combination with other STB resistance genes, and our study provides tools for rapid lab - based tracing of Stb6 in wheat breeding lines,» says Kanyuka.
Most resistance genes, in wheat and other plants, code for protein receptors located inside cells; the Stb6 gene codes for a receptor protein on the cell's surface.
The genes encoding NDM - 1 and other antibiotic resistance factors are usually carried on plasmids — circular strands of DNA separate from the bacterial genome — making it easier for them to spread through populations.
«Because TIA - 1 is known to suppress COX - 2 expression in other cells, we reasoned that the inactivation of the TIA - 1 gene would increase COX - 2 expression in neurons and, consequently, would increase resistance to acute seizures,» he continues.
We assume that phages acquire resistance genes from already resistant bacteria and then transfer those genes to other bacteria,» says Hilbert.
Researchers will also want to find out whether bacterial integrons of other species can also pick up genes besides those for antibiotic resistance.
Others might be engineered to include nutrients like beta carotene, iron, and vitamin A. Instead of one gene to fight off insects or disease, crops will be engineered with «stacks» of resistance genes to prevent pests from evolving resistance to a single approach.
They did, however, find copies of genes related to CDR1, CDR2, and few others that encode other transporters associated with drug resistance — although the way they function in C. krusei is unknown.
The other possibility is that resistance genes will migrate from the crop to the weeds.
«It is incredibly tempting to assume that antibiotics are promoting the spread of resistance by increasing the rate at which bacteria share resistant genes with each other, but our research shows they often aren't.»
Others were similar to existing resistance genes, but not precisely the same.
Gene therapy could impart this kind of resistance to others.
Previous research by Professor Keevil and Dr Warnes has proved copper's efficacy against norovirus, influenza and hospital superbugs, such as MRSA and Klebsiella, plus stopping the transfer of antibiotic resistance genes to other bacteria to create new superbugs.
Prof Bentzen from Dalhousie University said: «Although this study focused on MHC genes in vertebrates, the evolutionary dynamics described in it likely apply to other gene families, for example resistance genes and those which prevent self - fertilization in plants (self - incompatibility loci) that are caught up in their own evolutionary races.»
Lee says the research team will measure the amount of methylation in patients» cells when they begin their treatment and the presence of genes associated with irinotecan resistance, among other possible biomarkers.
By transferring only the genes necessary for disease resistance, Gray says the technique may leave the vine's other traits intact.
Perhaps most alarming to some scientists is that 21 % of the lab moths carried the resistance gene — a rate 10 times higher than that seen in any other bug.
But because some of the genes could indicate pathogenic characteristics — such as resistance to antibiotics — the researchers want to learn more about the potential health implications, and whether other buildings house similar biofilms.
Both the carbapenem resistance and the colistin resistance genes are on separate plasmids, which means in principle they could spread to other bacteria.»
Many other applications are arising — for example, Lapitan's lab discovered that inhibiting one gene can broaden wheat's resistance to the devastating Russian wheat aphid.
Non-flowering plants could also ensure the containment of genes for herbicide resistance (or other traits conferred to the organisms), counteracting the concern that transgenic trees would spread their lab - produced genetics throughout nearby wild forest.
These genes exist on plasmids, small segments of DNA that are capable of moving from one bacterium to another, potentially spreading antibiotic resistance to other bacterial species.
So for example, if one microbe is resistant to antibiotics and the other one isn't, if we let them have sex, maybe one of them will pass the resistance gene on to the other one and we can figure out where it is by seeing how long it takes for that gene to get from one microbe to the other.
Under these conditions, natural selection may be favoring genes that confer resistance to disease, such as AIDS and malaria, or enhance reproductive fitness in other ways, researchers said in a report in Science.
In other research, a knockout of the gene that encodes one type of lncRNA in mice conferred some resistance to obesity caused by a high - fat diet.
But what our studies suggest is that there is a whole new universe where you can now screen for other functions, like the ability to block conjugation or to induce the loss of resistance genes.
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