Not exact matches
The two receptors are homologous with each
other,
rhodopsin, and
other receptors coupled to guanine nucleotide regulatory proteins and they contain seven hydrophobic domains, which may represent transmembrane spanning segments.
Fun fact: Unlike
others of its kind, A. hoosieri lacks a debilitating mutation in the
rhodopsin gene, which is an important gene for vision.
Although the location of carazolol in the β2 - adrenergic receptor is very similar to that of retinal in
rhodopsin, structural differences in the ligand - binding site and
other regions highlight the challenges in using
rhodopsin as a template model for this large receptor family.