Sentences with phrase «other rodent models»

For such study, we have used the McGill - R - Thy1 - APP transgenic rat, which is unique compared to other rodent models in that the AD - like phenotype has been achieved with a single genomic insertion of a mutated human APP transgene; minimizing off - target genetic corruption and therefore being closer to the human disease [32].

Other rodent models that utilize changes in expression of α - synuclein have also reported lower anxiety levels.

Not exact matches

Also, research in other animal models, such as rodents, has shown anesthesia exposure early in life can lead to cell death in the brain and cognitive impairments.

Researchers using a rodent model of childhood manganese exposure have found that too much manganese early in development causes lasting attention deficits and other impairments.

In other places the authors extrapolate inappropriately from data on rodent models or data relating to different health outcomes (e.g. cancer).

Today, there are more DIO rodent models made using our diets than any other diets in the world.

Importantly, unlike human or other diet - induced rodent models of NAFLD, rodents fed MCD diets lose weight (due to a vastly lower caloric intake) and do not become insulin resistant (9, 19).

To conduct the study, Sanjabi and her team created a new model of viral infection through the rectum that uses lymphocytic choriomeningitis virus (LCMV), a rodent virus often used in research to model other pathogens.

The scientists validated their findings with another RNA virus called lymphocytic choriomeningitis virus (LCMV), which is a rodent virus often used in research to model other pathogens.

We selected mice as the rodent species with which to prove this concept as they are a major agricultural, health and conservation pest, they are the most sophisticated animal model, and this knowledge base can be leveraged, and naturally occurring genetic elements known in mice but not other species can be exploited.

In dramatic contrast to the poor repair outcomes for humans and rodent models such as mice, salamanders are able to completely regenerate heart tissue, whole limbs and many other tissues following injury, at any life stage.

Functional studies in rodent models suggest that OPHN1 linked ID is a consequence of abnormal synaptic transmission and shares common pathophysiological mechanisms with other cognitive disorders.

She will discuss the Systems Biology approaches currently used to understand the Omics results from space flight model systems (rodent, fruit fly etc) in the context of tissue response (i.e. muscle, liver, other vital organs).

In other research a rodent model of TBI was used to show that CNB - 001 significantly reversed the behavioural deficits in both locomotion and memory that come with the brain injury.

In rodents, ketogenic diets reduce reactive oxygen species in the brain34 and reduce central inflammation and reactive oxygen species in a model of multiple sclerosis.35 Two clinical papers have found that ketogenic diet feeding of 12 weeks to 6 months reduced signs of liver inflammation in obese patients with nonalcoholic fatty liver disease (in addition to improving various other physiological and biochemical variables).36, 37 Unfortunately, basic research into non-alcoholic fatty liver disease has been hampered by species differences between mice and humans in their hepatic reaction to ketogenic diets.38

Other than the amount of maternal care, the consistency over time of that care and the exposure to novelty are also very important not only in rodents (23, 75) but also, monkey models (76).