Sentences with phrase «other sequence variation»

Not exact matches

biochemical evidence such as Cytochrome - cyto - C is just one of the thousands of sequences and is not proof of common ancestry, as there are more variations than similarities in the genetic code, on the other hand a study of the amino acid make - up reveals that man is closer to lamprey than are fish.

«It can handle multiple biomarker technologies simultaneously, such as complex flow cytometry, next - generation sequencing, immunosequencing, epigenetic profiling, and other types of asssys measuring biological variation as well,» says Marshall.

Trent and others says that the same mechanism might be at work in genes linked to other cancers, such as breast and prostate cancer, which have been found to contain similar «harmless» sequence variations.

Slight variations of this problem appear in many other areas of research, such as DNA sequencing, moving an automated soldering tip to many soldering points, or routing packets of data through processing nodes.

Hariri said he hopes that other researchers looking for biomarkers of mental illness will begin to consider methylation above and beyond DNA sequence - based variation and across different tissues.

Researchers report that one tiny variation in the sequence of a gene may cause some people to be more impaired by traumatic brain injury (TBI) than others with comparable wounds.

Using high - throughput sequencing of whole genomes will also be key in finding other kinds of genetic variation involved in autism, Grice explained.

The work on gorilla and other human genomes clearly demonstrates that large swathes of genetic variation can't be understood with the short sequence - read approaches.

They looked for variations in the sequences that revealed how closely or distantly related these lineages are and when they might have begun diverging from each other.

This section invites manuscripts describing (a) Linkage, association, substitution or positional mapping and epigenetic studies in any species; (b) Validation studies of candidate genes using genetically - engineered mutant model organisms; (c) Studies focused on epistatis and gene - environment interactions; (d) Analysis of the functional implications of genomic sequence variation and aim to attach physiological or pharmacogenomic relevance to alterations in genes or proteins; (e) Studies of DNA copy number variants, non-coding RNA, genome deletions, insertions, duplications and other single nucleotide polymorphisms and their relevance to physiology or pharmacology in humans or model organisms, in vitro or in vivo; and (f) Theoretical approaches to analysis of sequence variation.

His research group provided the first genome - wide view of segmental duplications within human and other primate genomes and he is a leader in an effort to identify and sequence normal and disease - causing structural variation in the human genome.

Now, as technologies have further evolved, the Broad's Center for Common Disease Genomics, together with other NHGRI centers, will seek to use whole genome sequencing to create a comprehensive catalog of the genetic variation associated with disease.

New technologies allow extensive sequencing to be carried out to analyse sequence variation, transcription, epigenetics and other phenomena.

In this study, the research team searched for gene mutations - or other variations in the genome - that may have a direct effect on the risk of pathologically low - bone density among a large set of sequence variants.

However, being a complex multistep process, cancer cytogenetics are broadened to «cytogenomics,» with complementary resources on: general databases (nucleic acid and protein sequences databases; cartography browsers: GenBank, RefSeq, UCSC, Ensembl, UniProtKB, and Entrez Gene), cancer genomic portals associated with recent international integrated programs, such as TCGA or ICGC, other fusion genes databases, array CGH databases, copy number variation databases, and mutation databases.

Other uses of having a known link between multiple DNA sequencing reads includes studies of structural variations in for instance cancer cells, and when linking functional genes to taxonomic groups in microbial communities.

Here, we discuss and illustrate the strengths and weaknesses of approaches for the annotation and classification of important elements of protein - coding genes, other genomic elements such as pseudogenes and the non-coding genome, comparative - genomic approaches for inferring gene function, and new technologies for aiding genome annotation, as a practical guide for clinicians when considering pathogenic sequence variation.

Thus, previously reported sequence diversity between different strains in the 2006 study by Urisman, et al. [1] and presumably in other fully - or partially - sequenced XMRV genomes appears to arise from Taq polymerase errors introduced during PCR and / or sequencing [47], and not from natural genetic variation.

The focus of the conference was connecting how epigenetics (cellular and physiological phenotypic trait variations that are caused by external or environmental factors that switch genes on and off and affect how cells read genes instead of being caused by changes in the DNA sequence — in other words nutrition and lifestyle choices) impact whether or not an individual actually develops a specific health issue even though they have a SNP mutation.

The variation of Upavistha Konasana (Wide - Angle Seated Forward Bend) used in this sequence maximizes the lateral arc of your body, and this creates more stretch than any other movement on certain muscles that run vertically up the sides of the vertebrae or the back of the rib cage.

You'll come across the Guardians of the Galaxy, multiple variations of Spider - Man (who have rather funny dialogue sequences between each other), and dozens upon dozens more.