Sentences with phrase «other small clinical trials»

Two other small clinical trials evaluated the effects of supplementation with 200 mg zinc sulfate (providing 45 mg zinc) for 2 years in subjects with drusen or macular degeneration.

Not exact matches

Some small studies have suggested that synbiotics could provide benefits to a range of other conditions influenced by the gut microbiome as well, including obesity, diabetes, and non-alcoholic fatty liver disease, but larger - scale clinical trials focusing on each of those conditions are needed.

Although some SIDS experts and policy - makers endorse pacifier use recommendations that are similar to those of the AAP, 272,273 concerns about possible deleterious effects of pacifier use have prevented others from making a recommendation for pacifier use as a risk reduction strategy.274 Although several observational studies275, — , 277 have found a correlation between pacifiers and reduced breastfeeding duration, the results of well - designed randomized clinical trials indicated that pacifiers do not seem to cause shortened breastfeeding duration for term and preterm infants.278, 279 The authors of 1 study reported a small deleterious effect of early pacifier introduction (2 — 5 days after birth) on exclusive breastfeeding at 1 month of age and on overall breastfeeding duration (defined as any breastfeeding), but early pacifier use did not adversely affect exclusive breastfeeding duration.

Several other small companies, including Bentley Pharmaceuticals in Exeter, N.H., are conducting clinical trials on insulin nasal sprays as well.

AG1295 won't work inside the body because it can't get to the marrow, but Small says his team has already identified other FLT3 inhibitors potentially useful for patients, and clinical trials are just around the corner.

A drug used for decades to treat high blood pressure and other conditions has shown promise in a small clinical trial for autism.

The reliably high percentage of those who develop viremia following exposure to this challenge virus is another advantage — when most or all volunteers develop viremia or other signs of infection, clinical trials can enroll relatively small numbers of people but still achieve answers to such questions as whether a candidate vaccine protects against infection, she noted.

The study, published in the July issue of the journal Epidemiology, offers benefits over typically used randomized clinical trials, as such studies are often too small to identify rare side effects or may be performed in a group of patients who do not take other types of medications or have other conditions that could skew the drug's effect in a broader group following approval.

Or if used in a vaccine, they may be most effective in combination with other drugs: a few patients in the small clinical trials whose cancer relapsed after the trials responded to treatment with a checkpoint inhibitor.

Although these platforms can be used successfully for small - scale expansion of hMSCs, other platforms will be required to generate the quantity of cells required to support the increasing number of clinical trials utilizing hMSCs and the subsequent large - scale production.

Table 1: Selection, Design & Construction of HSV - based Oncolytic Viruses Table 2: Selection, Design & Construction of Adenovirus - based Oncolytic Viruses Table 3: Selection, Design & Construction of Vaccinia Virus - based Oncolytic Viruses Table 4: Selection, Design & Construction of Vesicular Stomatitis Virus - based Oncolytic Viruses Table 5: Selection, Design & Construction of Newcastle Disease Virus - based Oncolytic Viruses Table 6: Selection, Design & Construction of Various Virus - based Oncolytic Viruses Table 7: Current Company - Sponsored Clinical Trials of T - Vec Table 8: Clinical Trials of ColoAd1 Table 9: Clinical Trials with JX - 594 Table 10: Clinical Trials with GL - ONC1 Table 11: Clinical Trials of CAVATAK (CVA21) Table 12: Clinical Trials with MV - NIS Table 13: Overview of Oncolytic Viruses by Development Phase & Virus Family Table 14: Profile of Approved and Marketed Oncolytic Viruses Table 15: Pivotal Study Design of Oncolytic Viruses in Late Stage Development Based on Previous Clinical Results Table 16: Approved Indications of Immune Checkpoint Inhibitors Table 17: Active Clinical Studies of Oncolytic Viruses in Combination with Immune Checkpoint Inhibitors (ICI) Table 18: Planned Clinical Studies of Oncolytic Viruses in Combination with Immune Checkpoint Inhibitors (ICI) Table 19: Active or Planned Clinical Studies of Oncolytic Viruses in Combination with Other Anti-Cancer Therapeutics Table 20: Pattern of Transgenes in Oncolytic Viruses in Relation to Development Phase Tables 21a and 21b: Indications and Frquency and Way of Administration of Oncolytic Viruses in Active and / or Positive Completed Clinical Studies Table 22: Small and Medium Pharma & Biotech as Partner for Regional Co-Development of Oncolytic Viruses Table 23: Immuno - Oncology Portfolio of Major Pharma & Biotech with Interest in Oncolytic Viruses Table 24: Interests of Major Pharma & Biotech in Oncolytic Viruses Table 25: First Generation Oncology Virus Companies and their Sources of Technology Table 26: Second Generation Oncology Virus Companies and their Sources of Technology Table 27: Third Generation Oncology Virus Companies and their Sources of Technology Table 28: Fourth Generation Oncology Virus Companies and their Sources of Technology Table 29: Grants, Credits & Donations Table 30: Financing by Venture Capital, Private Equity and Other Private Placements Table 31: Collaboration & Licensing Agreements Table 32: Companies Listed on Stock Exchange & Offerings Table 33: Mergers & Acquisitions

Clinical benefits of lentiviral vectors have been observed in small trials for other diseases, including the common hematopoietic disorders

A Clinical Core has capability to safely and efficiently distribute clinical studies of vaccine immunosafety for biomarker discovery from small intensive trials to large - scale studies of adult, paediatric and other popuClinical Core has capability to safely and efficiently distribute clinical studies of vaccine immunosafety for biomarker discovery from small intensive trials to large - scale studies of adult, paediatric and other popuclinical studies of vaccine immunosafety for biomarker discovery from small intensive trials to large - scale studies of adult, paediatric and other populations.

Since the small victory, Catherine and her foundation have continued to push for more fecal microbiota transplant (FMT) clinical trials aimed at other digestive disorders, more research funding and more public awareness and education.

Reviews of clinical trials on hypnosis have concluded that the evidence of its effectiveness for smoking cessation is insufficient, but other research shows promise: The preliminary results from a small 2007 study of smokers hospitalized with cardiopulmonary diseases showed that the patients who chose to participate in a hypnotherapy session were more likely to be nonsmokers six months later than patients who chose nicotinereplacement therapy (NRT) alone.

To accomplish our mission, we serve as a «one - stop - shop» for our veterinary faculty, other campus units and study sponsors by providing clinical technical expertise, administrative support and financial oversight for small and large animal clinical trials in multiple disciplines, including (but not limited to) ophthalmology, oncology, neurology, cardiology, dermatology, diagnostic imaging, dentistry, internal medicine, orthopedics and soft tissue surgery.

First, the effect sizes are smaller both in absolute terms and in comparison to effect sizes reported elsewhere — for example, in the UK, the National Institute for Health and Clinical Excellence reported effects of 1.7 for waiting list versus trauma focused psychological therapies and 1.18 for other active interventions for PTSD.1 Second, there are problems with the small number of trials in key areas (for example, TAU / WL n = 5), with the combining of different outcomes from the same study in the meta - analysis and the failure to consider clinical as opposed to statistical signiClinical Excellence reported effects of 1.7 for waiting list versus trauma focused psychological therapies and 1.18 for other active interventions for PTSD.1 Second, there are problems with the small number of trials in key areas (for example, TAU / WL n = 5), with the combining of different outcomes from the same study in the meta - analysis and the failure to consider clinical as opposed to statistical signiclinical as opposed to statistical significance.