To use fructose for energy, the body needs to convert it into another type of simple sugar called glucose or into
other smaller molecules.
These effector proteins and
other small molecules in their spit cause the root cell to forego normal processes and create a huge feeding site called a syncytium.
Coincidentally, co-author Lawrence Shapiro, PhD, at Columbia, was building a crystal structure of cadherin - 11 and is now working with Byers and Brenner to show how the molecule binds to Celebrex and
other small molecule drug cadherin - 11 inhibitors.
She and her colleagues are now searching for
other small molecules that could be used to inhibit Wnt and promote FCSC growth.
First, the fungi accumulate sugars and
other small molecules in their cells, which, in turn, brings in more water.
Vividion will develop targeted protein degraders and
other small molecules in a new partnership with Celgene.
Finally, the strategy applied here for selective delivery of MK801 can be extended to
other small molecules for use in brain tissue (Tian et al., 2012), allowing for an approach that combines chemistry, molecular genetics, and neurobiology to dissect cell signaling pathways in specific cell types in the central nervous system.
On a University of Texas website they write «We conclude that the vibrational degrees of freedom of HCl, or
any other small molecule, are frozen out at room temperature.»
Not exact matches
BioNTech, which has around 700 employees at sites in Germany — more than any
other unlisted biotech firm in Europe — is also working on
other cancer - fighting technologies, including antibodies, cell therapies and
small molecules.
Complete certainty exists among essentially all biochemists that the
other characteristics of living organisms (for example, selective permeability across all membranes, muscle contraction, and the hearing and memory process) will all be completely understood in terms of the coordinative interactions of large and
small molecules.2
Some things, like atoms and
molecules, can not be seen because they are too
small to be seen; but we can perceive them indirectly through electron microscopes and
other such instruments.
They are the principal component,
other than water, of all living forms, but the nucleic acids alone have the remarkable property of being capable of duplicating their patterns, whatever they may be, from
small molecules in their medium.
«We could apply the strategy used in this study to quickly identify and design
small molecule drugs for
other RNA - associated diseases,» explained study first author Sai Velagapudi, a research associate in the Disney lab.
The enzyme had previously been modified through directed evolution by the Arnold lab and
others to create
molecules containing
small rings of three carbon atoms — essentially half of a bicyclobutane group.
He worked on the organic synthesis of
molecules able to recognize and bind with
other,
smaller molecules, a phenomenon called molecular recognition, which had won Donald J. Cram, Jean - Marie Lehn, and Charles J. Pedersen the Nobel Prize in chemistry in 1987.
The speed with which the wave moves suggests that it travels through gap junctions and is made up either of calcium ions or some
other small signaling
molecule.
Other collaborations that are currently being discussed focus on the development of small molecules that could disrupt «kidney» (Malphigian tubule) function in mosquitoes, on the differences in the ability to transmit disease among various populations of Aedes aegypti and other mosquitoes, and on advances in the surveillance of adult mosqui
Other collaborations that are currently being discussed focus on the development of
small molecules that could disrupt «kidney» (Malphigian tubule) function in mosquitoes, on the differences in the ability to transmit disease among various populations of Aedes aegypti and
other mosquitoes, and on advances in the surveillance of adult mosqui
other mosquitoes, and on advances in the surveillance of adult mosquitoes.
This suggests that these
small molecules, and possibly
others, might be clinically relevant biomarkers of mTBI.
Others include modification of the histone proteins that DNA winds around to form chromatin — the tightly packed cluster that makes up chromosomes — and the activation of
small non-coding RNA
molecules.
And ApoE is bound to fat, so it tends to stick to
other molecules in biochemical assays, says Menelas Pangalos, who leads research on
small -
molecule discovery at AstraZeneca in Macclesfield, UK, and has long had an interest in ApoE.
Some reactions slow down, but
others actually speed up — especially reactions that involve joining
small molecules into larger ones.
A class of
small molecules found in grapes, red wine, olive oil, and
other foods extends the life of yeast cells by approximately 70 % and activates genes known to extend life span in laboratory animals.
Unlike
other techniques that depend on the ability to calculate the nuclear structure from the original data, which works best for
small molecules, we only need to know the properties of our electron beam and experimental setup.»
Already, large companies such as DuPont are harnessing synthetic biology, and
small companies «are being built around the idea of using organisms, designing organisms, using tools of synthetic biology to make
molecules that can't be produced any
other way,» Glass says.
«Our findings will promote the development of specific
small -
molecule drugs useful to treat Graves» disease and
other dysfunctions of GPHRs.»
We don't need to use a cocktail of
small molecules, growth factors or
other supplements to create a population of bone cells from human pluripotent stem cells like induced pluripotent stem cells,» Varghese said.
This is the science of how atoms and
molecules react with each
other and how larger
molecules are constructed from
smaller ones.
Usually, in
small -
molecule junctions, electrons «pushed» through the junction by the applied bias make the leap continuously, from one electrode into the
other, so that the number of electrons on the
molecule at each instant of time is not well - defined.
On the
other hand, many deep questions drive science to
smaller scales, more minute than the realm of atoms and
molecules, or to a greater depth of detail underlying broad - brush answers to past big questions.
Many researchers who once focused on messenger RNA and
other relatively large RNA
molecules have in the past 5 years turned their attention to these
smaller cousins, including microRNA and
small nuclear RNA.
The approach should work with
other small -
molecule drugs and may lend itself to multiplexing, he notes, so numerous drugs could be measured at the same time.
Small RNA
molecules, many less than 30 bases, now share the limelight with
other gene regulators.
We found that immune cells secrete
molecules to
other cells across a very
small gap.
The polymer sucked up a variety of
other small organic
molecules faster than current materials, as well.
But it was not clear how
smaller molecules could have found each
other and built ribose in rigid ice.
However, this security system is so effective at protecting the brain that it prevents many life - saving drugs — all but some
small molecules — from being able to treat cancer and
other diseases of the brain.
As target depth increases, the single - scattered signal (red) becomes negligibly
small, because it is more likely that the waves will get bounced around by
other biological
molecules in their path (blue).
The design inspiration for the new particles came from the natural world — specifically,
small particles known as lipoproteins, which transport cholesterol and
other fatty
molecules throughout the body.
«What that means is that binding of
small molecules further away from the part of the protein that's actually involved with the interaction with
other proteins or substrates — that's what you want to prevent — impacts interaction via
other parts of the protein.»
Taking yet another tack, physicist Jan Hendrik Schn, with help from
other researchers at Bell Laboratories, has refined a technique he recently described for making transistors out of a layer of
small carbon
molecules.
The research team has been using NMR — a technique related to the one used in MRI body scanners and capable of visualising
molecules at the
smallest scales — to examine how
small components of herpes virus help it to multiply by binding themselves with
other large
molecules; this produced images of a monkey herpes virus protein interacting with mouse cellular protein and viral RNA.
At present, most instruments on astrobiology missions look for habitable conditions,
small organic
molecules and
other «biosignatures» that generally could not be formed without life.
Instead of using the chemically linked long - chain
molecules found in traditional rubbers, Ludwik Leibler and his colleagues at the Centre National de la Recherche Scientifique in Paris thought they could make stretchy materials from much
smaller building blocks that associate with each
other in a network.
«Although the two types of inhibitory neurons are very similar to each
other in terms of morphology, synaptic connectivity, and the kinds of
small molecules they use for signaling, they're very different in terms of the methylation pattern.
To make the findings more relevant to patients, they are also examining direct cellular conversion strategies using
small molecules and
other non-viral methods.
The head of α - actinin binds actin whilst two
small L - shaped parts sit at the end of the rod and interact with the neck of the
other molecule.
«They also provide a promising strategy for identifying
small molecule drugs designed to treat Alzheimer's disease and
other neurological disorders.»
Towards reducing the global burden of malaria and
other neglected diseases, millions of compounds were screened, prioritized and assembled by the WHO - supported Medicines for Malaria Venture (MMV) as the MMV «Malaria Box» collection of 400 chemically diverse
small molecules.
Regular
small oil spills in
other marine waters have adapted («learned») microbes to eat oil
molecules.
Small molecules that latch on to the body's cannabinoid receptors can make
other docking sites on the receptor change shape to fit the body's natural cannabinoids.