Sentences with phrase «other smaller molecules»

To use fructose for energy, the body needs to convert it into another type of simple sugar called glucose or into other smaller molecules.
These effector proteins and other small molecules in their spit cause the root cell to forego normal processes and create a huge feeding site called a syncytium.
Coincidentally, co-author Lawrence Shapiro, PhD, at Columbia, was building a crystal structure of cadherin - 11 and is now working with Byers and Brenner to show how the molecule binds to Celebrex and other small molecule drug cadherin - 11 inhibitors.
She and her colleagues are now searching for other small molecules that could be used to inhibit Wnt and promote FCSC growth.
First, the fungi accumulate sugars and other small molecules in their cells, which, in turn, brings in more water.
Vividion will develop targeted protein degraders and other small molecules in a new partnership with Celgene.
Finally, the strategy applied here for selective delivery of MK801 can be extended to other small molecules for use in brain tissue (Tian et al., 2012), allowing for an approach that combines chemistry, molecular genetics, and neurobiology to dissect cell signaling pathways in specific cell types in the central nervous system.
On a University of Texas website they write «We conclude that the vibrational degrees of freedom of HCl, or any other small molecule, are frozen out at room temperature.»

Not exact matches

BioNTech, which has around 700 employees at sites in Germany — more than any other unlisted biotech firm in Europe — is also working on other cancer - fighting technologies, including antibodies, cell therapies and small molecules.
Complete certainty exists among essentially all biochemists that the other characteristics of living organisms (for example, selective permeability across all membranes, muscle contraction, and the hearing and memory process) will all be completely understood in terms of the coordinative interactions of large and small molecules.2
Some things, like atoms and molecules, can not be seen because they are too small to be seen; but we can perceive them indirectly through electron microscopes and other such instruments.
They are the principal component, other than water, of all living forms, but the nucleic acids alone have the remarkable property of being capable of duplicating their patterns, whatever they may be, from small molecules in their medium.
«We could apply the strategy used in this study to quickly identify and design small molecule drugs for other RNA - associated diseases,» explained study first author Sai Velagapudi, a research associate in the Disney lab.
The enzyme had previously been modified through directed evolution by the Arnold lab and others to create molecules containing small rings of three carbon atoms — essentially half of a bicyclobutane group.
He worked on the organic synthesis of molecules able to recognize and bind with other, smaller molecules, a phenomenon called molecular recognition, which had won Donald J. Cram, Jean - Marie Lehn, and Charles J. Pedersen the Nobel Prize in chemistry in 1987.
The speed with which the wave moves suggests that it travels through gap junctions and is made up either of calcium ions or some other small signaling molecule.
Other collaborations that are currently being discussed focus on the development of small molecules that could disrupt «kidney» (Malphigian tubule) function in mosquitoes, on the differences in the ability to transmit disease among various populations of Aedes aegypti and other mosquitoes, and on advances in the surveillance of adult mosquiOther collaborations that are currently being discussed focus on the development of small molecules that could disrupt «kidney» (Malphigian tubule) function in mosquitoes, on the differences in the ability to transmit disease among various populations of Aedes aegypti and other mosquitoes, and on advances in the surveillance of adult mosquiother mosquitoes, and on advances in the surveillance of adult mosquitoes.
This suggests that these small molecules, and possibly others, might be clinically relevant biomarkers of mTBI.
Others include modification of the histone proteins that DNA winds around to form chromatin — the tightly packed cluster that makes up chromosomes — and the activation of small non-coding RNA molecules.
And ApoE is bound to fat, so it tends to stick to other molecules in biochemical assays, says Menelas Pangalos, who leads research on small - molecule discovery at AstraZeneca in Macclesfield, UK, and has long had an interest in ApoE.
Some reactions slow down, but others actually speed up — especially reactions that involve joining small molecules into larger ones.
A class of small molecules found in grapes, red wine, olive oil, and other foods extends the life of yeast cells by approximately 70 % and activates genes known to extend life span in laboratory animals.
Unlike other techniques that depend on the ability to calculate the nuclear structure from the original data, which works best for small molecules, we only need to know the properties of our electron beam and experimental setup.»
Already, large companies such as DuPont are harnessing synthetic biology, and small companies «are being built around the idea of using organisms, designing organisms, using tools of synthetic biology to make molecules that can't be produced any other way,» Glass says.
«Our findings will promote the development of specific small - molecule drugs useful to treat Graves» disease and other dysfunctions of GPHRs.»
We don't need to use a cocktail of small molecules, growth factors or other supplements to create a population of bone cells from human pluripotent stem cells like induced pluripotent stem cells,» Varghese said.
This is the science of how atoms and molecules react with each other and how larger molecules are constructed from smaller ones.
Usually, in small - molecule junctions, electrons «pushed» through the junction by the applied bias make the leap continuously, from one electrode into the other, so that the number of electrons on the molecule at each instant of time is not well - defined.
On the other hand, many deep questions drive science to smaller scales, more minute than the realm of atoms and molecules, or to a greater depth of detail underlying broad - brush answers to past big questions.
Many researchers who once focused on messenger RNA and other relatively large RNA molecules have in the past 5 years turned their attention to these smaller cousins, including microRNA and small nuclear RNA.
The approach should work with other small - molecule drugs and may lend itself to multiplexing, he notes, so numerous drugs could be measured at the same time.
Small RNA molecules, many less than 30 bases, now share the limelight with other gene regulators.
We found that immune cells secrete molecules to other cells across a very small gap.
The polymer sucked up a variety of other small organic molecules faster than current materials, as well.
But it was not clear how smaller molecules could have found each other and built ribose in rigid ice.
However, this security system is so effective at protecting the brain that it prevents many life - saving drugs — all but some small molecules — from being able to treat cancer and other diseases of the brain.
As target depth increases, the single - scattered signal (red) becomes negligibly small, because it is more likely that the waves will get bounced around by other biological molecules in their path (blue).
The design inspiration for the new particles came from the natural world — specifically, small particles known as lipoproteins, which transport cholesterol and other fatty molecules throughout the body.
«What that means is that binding of small molecules further away from the part of the protein that's actually involved with the interaction with other proteins or substrates — that's what you want to prevent — impacts interaction via other parts of the protein.»
Taking yet another tack, physicist Jan Hendrik Schn, with help from other researchers at Bell Laboratories, has refined a technique he recently described for making transistors out of a layer of small carbon molecules.
The research team has been using NMR — a technique related to the one used in MRI body scanners and capable of visualising molecules at the smallest scales — to examine how small components of herpes virus help it to multiply by binding themselves with other large molecules; this produced images of a monkey herpes virus protein interacting with mouse cellular protein and viral RNA.
At present, most instruments on astrobiology missions look for habitable conditions, small organic molecules and other «biosignatures» that generally could not be formed without life.
Instead of using the chemically linked long - chain molecules found in traditional rubbers, Ludwik Leibler and his colleagues at the Centre National de la Recherche Scientifique in Paris thought they could make stretchy materials from much smaller building blocks that associate with each other in a network.
«Although the two types of inhibitory neurons are very similar to each other in terms of morphology, synaptic connectivity, and the kinds of small molecules they use for signaling, they're very different in terms of the methylation pattern.
To make the findings more relevant to patients, they are also examining direct cellular conversion strategies using small molecules and other non-viral methods.
The head of α - actinin binds actin whilst two small L - shaped parts sit at the end of the rod and interact with the neck of the other molecule.
«They also provide a promising strategy for identifying small molecule drugs designed to treat Alzheimer's disease and other neurological disorders.»
Towards reducing the global burden of malaria and other neglected diseases, millions of compounds were screened, prioritized and assembled by the WHO - supported Medicines for Malaria Venture (MMV) as the MMV «Malaria Box» collection of 400 chemically diverse small molecules.
Regular small oil spills in other marine waters have adapted («learned») microbes to eat oil molecules.
Small molecules that latch on to the body's cannabinoid receptors can make other docking sites on the receptor change shape to fit the body's natural cannabinoids.
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