Sentences with phrase «other transcription factors»

Previous research found that Short - root activates other transcription factors as well, creating a cascade in which each gene - regulating protein controls the next in the root development pathway.

So what we think is that probably in many cells in this section, all cells, the chromatin is encountered in a specific state, and in order to render the cell is permissive to reprogramming, you have to overcome these certain epigenetic modifications that block, for example, the binding of Ascl1 to its target chains, or the binding of other transcription factors to its target chains, then this way interfere with the possibility of reprogramming.

They may exert a transcriptional function or act as comodulators for other transcription factors.

and other transcription factors play in turning genes on and off in melanocytes and melanomas.

(And imagine the ramifications if the altered proteins are transcription factors that activate the genes coding for still other transcription factors!)

As alluded to before, employing other transcription factors causes astroglia to convert into other types of neurons.

DAXX recruitment to enhancers was at the nucleosome - free region, alongside other transcription factors and co-factors (Figure 1D).

Meanwhile, when a transcription error occurs, the complex of unfinished RNA and polymerizing enzymes stalls until GreA and other transcription factors enable the removal of the incorrect nucleotide.

David (Monash University, Victoria, Australia) has uniquely influenced analysis of flower development, initially by contributing to development of the ABC model for flower development, and more recently by studying other transcription factor families involved in flower morphogenesis.

Thus, a dual mechanism including the involvement of ATP hydrolysis and recruitment of other transcription factors (e.g., Sp1) would seem to occur with DDX3 - mediated transcriptional regulation.

STAT1 and STAT2 represent two of the seven mammalian STAT proteins that share several structurally and functionally conserved domains, including an NH2 - terminal coiled - coil region for interactions with other transcription factors and chaperone proteins, a phosphotyrosine - binding Src homology 2 domain required for receptor binding and STAT dimerization, and a COOH - terminal transcription activation domain (TAD) within which a highly conserved tyrosine residue is present.

Berninger and others have previously shown that Sox2, Ascl1, and other transcription factors — proteins that bind to specific DNA sequences to control the activity of genes — can induce the nonneuronal «support cells» known as glia to turn into neurons.

She likens TCF - 1 to an icebreaker ship that initially opens the ice (condensed, closed chromatin) and keeps a path available for other ships (other transcription factors that work in later stages of development) to steam through the now - open water (unwound chromatin).

If one of the proteins was absent, at times the other transcription factors would go rogue, binding to places on the genome where they were not supposed to be.

TCF - 1 is like an icebreaker ship that initially opens the ice (condensed, closed chromatin) and keeps a path available for other ships (other transcription factors that work in later stages of development) to steam through the now - open water (unwound chromatin).

By learning the rules for these three proteins, the scientists say they can infer the rules of other transcription factors that are also important for heart development.

Amphimedon lacks Hox genes and some other transcription factor subfamilies that are involved in specifying and patterning bilaterian nervous systems and body plans13, 14,27,36,37.