Sentences with phrase «other tumor models»

«It would be great to see this in other tumor models.»

Not exact matches

In the Cell study, Dr. Massagué, with Fellow Manuel Valiente, PhD, and other team members, found that in mouse models of breast and lung cancer — two tumor types that often spread to the brain — many cancer cells that enter the brain are killed by astrocytes.

The stem cell model says that tumor growth is more hierarchical, mainly driven by a subset of cells that can make new copies of themselves and give rise to the other cell types the tumor contains.

«In the future, our models should provide robust tools to screen for therapies that impact tumor dormancy and metastasis, and should also provide a platform to solve other biological mysteries that underlie dormancy.»

In experiments with cancer cell lines, the PIM1 inhibitors killed cells in a MYC - dependent manner, and in two different mouse models — one in which mice were implanted with patient tumors and the other in which a genetic alteration of MYC predisposes the mice to tumor development — the administration of PIM1 inhibitors resulted in significant tumor regression.

Their recent study, which appears as the cover article in the May issue of Cancer Research, shows that mathematical models can be used to predict how different tumor cell populations interact with each other and respond to a changing environment.

The next stage of research conducted by Prins and Liau will verify these findings in other brain tumor models.

In mouse models of cancer, targeted therapeutic inhibition of translation disrupts this survival response, dramatically slowing tumor growth and potentially rendering drug - resistant tumors vulnerable to other therapies.

Our PDX models and other next - generation cancer modeling platforms allow you to address critical questions in oncology research, such as unexplained drug resistance, drug efficacy, genomic heterogeneity in solid tumor, and the role of the immune system in drug response.

Other animal models either express oncogenes in a tissue - specific manner or shut down the expression of tumor suppressor genes in the whole tissue.

Other applications the lab is investigating include modeling tumors that metastasize to other parts of the Other applications the lab is investigating include modeling tumors that metastasize to other parts of the other parts of the body.

Finally, I have a category of «other cancers» with exomes published in 2011; these include pancreastic cysts and cell lines, gastric cancer tumors, and prostate cancer samples derived through mouse xenograft models.

Although this possibility has not yet attracted as much attention as the ideas of cell replacement, personalized medicine and other more direct clinical applications, hESCs are expected to be superior to most commonly used cell - culture models of drug discovery which employ tumor - derived or immortalized cell lines or primary cell culture.

After discussing similar effects in other animal models of cancer and a few studies showing the ability of antioxidants to prevent cancer growth, Campbell concluded that «a pattern was beginning to emerge: nutrients from animal foods increased tumor development while nutrients from plant - based foods decreased tumor development.»

In the mouse models, it was also able to stop tumors from growing and it helped other forms of chemotherapy to work more effectively.