Sentences with phrase «other tumor types»

They are being tested in dozens of other tumor types as well, so the competition will only get hotter.

Using cultured cells derived from human tumors of the breast and prostate gland, they confirmed that the IL6R / STAT3 / miR -34 a feedback loop is also activated in other tumor types.

This canine - derived, tumor - specific targeting approach is the first of its kind in the veterinary field and if successful this agent may also be used to treat many other tumor types in the dog.

A larger study to address this, as well as other fluorescent agents for other tumor types that do not express FRα, are being planned, Burggraaf added.

The study published in Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy cells.

Among these is BRG1 (also called SMARCA4) and the latest generation - sequencing technologies have extended these findings to other tumor types evidencing that BRG1 inactivation is widespread in cancer.

The level of NY - ESO - 1 expression in colorectal and several other tumor types, however, is very low, limiting the efficacy of treatments that target NY - ESO - 1 in patients with these cancers.

It is important to differentiate osteosarcoma from other tumor types and diseases that occur within bones, such as bacterial, viral, or fungal infections.

This is an unusually large amount of drivers, not typical for many other tumor types, according the study's senior author Dr. Matthew Wilkerson, associate professor and Bioinformatics Director of The American Genome Center and the Collaborative Health Initiative Research Program at USU.

It will offer patients «off label» access to various drugs already used for other tumor types or purposes, and collect information on how they fare.

Swanton's lab has since followed the work with comprehensive spatial and temporal genetic analyses of other tumor types, including colorectal cancer, showing the ways that faulty DNA replication promotes chromosomal instability in cancer.

FDA - approved BRAF inhibitors are widely used in metastatic melanoma with much success, and their use is expanding to other tumor types and is being tested in earlier stages of melanoma.

Importantly, this dependency can be extended beyond follicular lymphoma to other tumor types.

Dr. Klauber - DeMore said that the next steps of her research team will involve determining how well the technique works with these other tumor types, as well as studying its effect on breast cancer.

But the other tumor types may require more aggressive measures to prevent relapse, including chemotherapy and sometimes investigational drugs.

«Our results clearly demonstrate a significant, although unexpected, role for specific gut bacteria in enhancing the immune system's response to melanoma and possibly many other tumor types,» said study director Thomas Gajewski, MD, PhD, professor of medicine and pathology at the University of Chicago.

Investigators also found genomic similarities between endometrial cancers and other tumor types.

To get there, researchers will need to resolve certain obstacles associated with CAR - T, including further customization of the technology to recognize specific / other tumor types, and predicting and limiting cross-reactivity, where CAR - T immune cells start attacking healthy cells as well.

The presence of p70S6K in the nucleus has been reported in other tumor types (35).

Similar effects of rapamycin have been shown in other tumor types.

Waldman continues to study cancer gene function in his Georgetown lab, and has recently identified a new cancer gene called STAG2 that is among the most commonly mutated genes in cancer, involved in causing bladder cancer, pediatric bone tumors, leukemia, brain tumors, and other tumor types.

These signaling molecules may also play a role in tumor development in other organs, and are being evaluated in melanoma and other tumor types.

The cancers with most Eph receptor mutations are shown; other tumor types have fewer or no Eph receptor mutations.

He continues to study cancer gene function in his Georgetown lab, and has recently identified a new cancer gene called STAG2 that is among the most commonly mutated genes in cancer, involved in causing bladder cancer, pediatric bone tumors, leukemias, brain tumors, and other tumor types.

Of course, a biopsy can be considered, and may be recommended since it is the only way to truly confirm the diagnosis (though less common than hemangiosarcoma, other tumor types can be seen on the heart, including chemodectomas, a variety of sarcomas, and mesothelioma), but in many cases this is deemed unnecessary, and the echocardiogram is all that needs to be done for the cardiologist to be comfortable making a certain enough diagnosis to move forward with treatment.

If we find that one or both of these scFv neutralize VEGF activity then we intend to identify commercial partners that will assist in generating canine monoclonal antibodies based on these scFv that could then enter clinical trials in patients with hemangiosarcoma or other tumor types that are associated with excess production of VEGF.

For example, while the cost of treating breast cancer remains relatively low (compared to other tumor types), by 2020 this cancer will incur the highest costs — about $ 20.5 billion — since there are expected to be many more women living with the disease.