Sentences with phrase «other type of tumor»

The other type of tumor is malignant, which push through nearby organs or may spread to other tissues.

The method is fast and inexpensive and should be applicable to other types of tumors than colon cancer.»

«A number of other types of tumors have been shown to be driven by chimeras, but this one is unique — it codes for a kinase, an enzyme that modifies other proteins, that has not been identified in cancers.»

The Heidelberg epidemiologists now plan to extend their investigation to other types of tumor.

«Agents that block the proteins — CDK4 / 6 inhibitors — have received Food and Drug administration approval for some patients with metastatic breast cancer, but they've also shown promise against others types of tumors in clinical trials.

While most (80 %) of the tumors that develop are fibrosarcomas, other types of tumors that can develop through this phenomenon include:

Rodents can get many other types of tumors, but most of these are less common.

Clinically, skin tumors resemble several other types of tumor so definitive diagnosis relies upon microscopic examination of tissue by cytology or histopathology.

Lipomas can be found all over the body and are usually softer or more «squishy» than other types of tumors.

Cancers in dogs, such as bone cancer, lymphoma and many other types of tumors, are almost identical to those same kinds found in humans and they tend to develop faster and run their course quicker, so it's an ideal way to see if a certain therapy will work.

Not exact matches

While it has shown promise for some types of tumors and become standard of care for others, researchers are just beginning to explore how different immunotherapy technologies can be applied to brain cancer.

In the Cell study, Dr. Massagué, with Fellow Manuel Valiente, PhD, and other team members, found that in mouse models of breast and lung cancer — two tumor types that often spread to the brain — many cancer cells that enter the brain are killed by astrocytes.

The study published in Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy cells.

The findings also have potential uses for most other types of solid tumors, including those affecting the lungs and ovaries, because the same protein and enzyme are involved, François said.

Triple - negative tumors are also more likely to spread and recur than other types of breast cancers.

This is important because tumors are not all alike and some types of tumor cells may respond differently to a specific drug than others, Skala pointed out.

«But mounting evidence confirming angiotropism and EVMM has revolutionized the knowledge of how cancer spreads through the body to the point that other scientists have confirmed the process in other solid tumor cell types such as pancreatic cancer.»

«We've had luck with other types of cancer in removing the brakes on the immune system to allow it to fight the tumors, but this has not been the case with glioblastoma,» said study author Anhua Wu, MD, PhD, of the First Hospital of China Medical University in Shenyang, China.

Purushotham points out, «The feasibility of intraoperative CLI as shown in this study, in combination with the wide applicability of F -18-FDG across a range of solid cancers, provides a stepping stone for clinical evaluation of this technology in other solid cancer types that also experience incomplete tumor resection due to close or involved margins.»

Philip Laipis of the University of Florida, who has also observed tumors in AAV vector - treated mice, agrees, at least for studies using a similarly high dose of AAV to target liver cells, which are more likely than other cell types to take up the AAV vector.

The stem cell model says that tumor growth is more hierarchical, mainly driven by a subset of cells that can make new copies of themselves and give rise to the other cell types the tumor contains.

But as with many other types of treatments, treating tumors with PDT can stimulate molecular signaling pathways that support tumor survival.

A nanoparticle drug - delivery system that combines two complementary types of anticancer treatment could improve outcomes for patients with pancreatic cancer and other highly treatment - resistant tumors while decreasing toxicity.

Researchers found that patients with a higher amount or higher proportion of an inflammatory protein called type 1 interferon beta compared with another inflammatory protein, type 1 interferon alpha, do not respond as well to tumor necrosis factor inhibitors as others.

Unlike other solid tumors, there has been limited progress in understanding the contribution of genetic risk factors to the development of uveal melanoma, researchers say, primarily due to the absence of comprehensive genetic data from patients as the large sample cohorts for this rare cancer type have not been available for research.

Across all four cancer types, the new method of selecting candidate genes based on inter-tumor variation in gene expression outperformed the other methods, including the standard method of comparing mean expression in adjacent normal and tumor tissues.

Although breast cancer was the initial focus and featured in the study published online today, the team has also conducted experiments with other types of solid tumors, with similar results.

«Since patients with many types of cancer have elevated levels of myeloisd cells in their blood, it's possible that other tumors could have a similar interaction with bone to increase myeloid cell production.»

Patients were stratified by number of brain metastases (1 vs. 2 - 3), primary cancer type (melanoma vs. other histology) and pre-operative tumor size (less than vs. greater than three centimeters).

Researchers investigating pediatric low - grade gliomas (PLGG), the most common type of brain tumor in children, have discovered key biological differences in how mutated genes combine with other genes to drive this childhood cancer.

Previous in vitro studies conducted by researchers in other countries showed that this molecule was able to reduce the multiplication and increase the mortality of cells from melanoma, the most aggressive type of skin cancer, as well as breast cancer and neuroblastoma, a tumor that typically affects patients aged 15 or younger.

«Our work outlines the genetic similarities of the tissue and cells in different types of tumors and shows the strong relationships mice can have to other human cancers too.»

Using cultured cells derived from human tumors of the breast and prostate gland, they confirmed that the IL6R / STAT3 / miR -34 a feedback loop is also activated in other tumor types.

Using this approach as a template, researchers could substitute other types of antibodies and vaccines to target different tumors.

The researchers» next steps will involve expansion of the biomarkers identified in this study to other cancer types, especially breast cancer, due to the hormonal input that is a common factor in gynecologic tumors.

This is an unusually large amount of drivers, not typical for many other tumor types, according the study's senior author Dr. Matthew Wilkerson, associate professor and Bioinformatics Director of The American Genome Center and the Collaborative Health Initiative Research Program at USU.

Confirmation of the biomarkers in other cancer types will facilitate further characterization and validation to provide mechanistic understanding of how and why these specific gene - targets become modulated to accentuate or inhibit tumor metastasis.

Of 10 patients with other types of cancer — including pancreatic, prostate, and uterine — who had mismatch repair mutations, in seven their tumors shrank or remained stable; the other three progresseOf 10 patients with other types of cancer — including pancreatic, prostate, and uterine — who had mismatch repair mutations, in seven their tumors shrank or remained stable; the other three progresseof cancer — including pancreatic, prostate, and uterine — who had mismatch repair mutations, in seven their tumors shrank or remained stable; the other three progressed.

It also may have helped several others by boosting the power of a new type of cancer drug that uses a different mechanism to unleash an immune attack on the tumor.

Unlike most other genomic testing programs, Profile tumor analysis is offered to all patients regardless of age, cancer type, or stage of the cancer.

Tumor profiling can also reveal rare mutations and other changes that make some cancers unusually responsive to targeted drugs — knowledge that can be applied to patients with a variety of cancer types.

In further studies, they plan to explore the role of autophagy in immune reactions toward other tumor cell types, to determine whether such therapies might be effective in a broad range of cancers.

«Our results clearly demonstrate a significant, although unexpected, role for specific gut bacteria in enhancing the immune system's response to melanoma and possibly many other tumor types,» said study director Thomas Gajewski, MD, PhD, professor of medicine and pathology at the University of Chicago.

«A growing body of evidence suggests that exosomes can facilitate crosstalk between cancer cells and other types of cells that are nearby in the microenvironment that surrounds the tumor,» said Hongyun Zhao, the first author of the eLife study.

Checkpoint inhibitors such as ipilimumab, nivolumab and pembrolizumab have had a dramatic impact on treatment of several tumor types, including melanoma, lung cancer, head and neck cancers and others.

This discovery has implications for the understanding of glioblastoma as well as others types of solid tumors.»

While some mutations are common to many types of cancers, other genetic changes may be unique to certain tumors.

Depending on characteristics such as how many tumor cells, blood vessel cells, and immune cells are touching each other, the tumor microenvironment can nearly triple the chance that a common type of breast cancer (estrogen - receptor positive / HER2 negative) that has reached the lymph nodes will also metastasize, Condeelis and colleagues showed in a 2014 study of 3,760 patients.

We need a new type of vaccine that uses select components of a microbe or tumor cell or other cause of disease, and administers these with other defined substances, such as adjuvants, that directly exploit immunology.»

Transplanting non-cardiac stem cells also increases the risk for tumor formation, as many of the cells turn into other cell types besides the target heart cells.