When
other vaccinia viruses come knocking, long projections of another protein, actin, shoot out from the cell membrane, causing the virus to bounce off.
The proteins work together to form a complex on the cell's surface that prevents
other vaccinia virus particles from entering (a process called superinfection).
Not exact matches
He wonders whether it's not
vaccinia, the
virus used to induce smallpox resistance, but some
other component of the vaccine that's prompting inflammation, perhaps bovine cells from the manufacturing process.
Cell biologist Michael Way of the London Research Institute agrees that
other viruses may also use the
vaccinia infection strategy.
The Pexa - Vec
virus was originally developed by Michael Mastrangelo, MD, and Edmund Lattime, PhD, of Thomas Jefferson University in Philadelphia, who engineered the harmless
vaccinia virus to infect only cancer cells and
other rapidly dividing cells, as well as to stimulate immune activity, in hopes of boosting the immune response to tumors.