Sentences with phrase «out of the cells control»

Specifically, researchers have learned that traffic in and out of the cells control center - the nucleus - breaks down in HD.

Not exact matches

They're hoping to find out what controls the size of the nucleus, the central compartment of a cell that contains the DNA, and other components of the cell as it develops into a many - celled organism.

As a physics teacher, I teach the therapeutic effects of gamma radiation in radiotherapy, along with the associated dangers (radiation can cause cells to become cancerous as well as kill cells that are already cancerous), but a common misconception among students is that cancer cells are rather like viruses or bacteria, a sort of alien cell that has entered the body, growing out of control with little relation to the surrounding cells.

, I mean came «into existence» (mysteriously popped out of nowhere); rather, it will challenge intellectual thinkers to look at life as not just a compilation of atoms / cells; rather a universe that is controlled by powers much more awesome than the natural forces we all experience on a daily basis.

In Mexico, Minebea Intec will offer an extensive range of weighing and inspection products, solutions and services for diverse manufacturing processes — from goods in to goods out, including platform scales, vessel and silo scales (load cells), checkweighers and equipment for detecting foreign objects (metal detectors and x-ray inspection systems), as well as software solutions for statistical process control and formulation applications.

The boosted genes had three main beneficial effects: improving the efficiency of mitochondria, the powerhouse of cells; boosting insulin production, which improves control of blood sugar; and preventing the depletion of telomeres, caps on chromosomes that help to keep DNA stable and so prevent cells wearing out and ageing.

The boosted genes had three main effects: improving cellular energy efficiency; upping insulin production, which improves control of blood sugar; and preventing the breakdown of caps on chromosomes that help prevent cells wearing out and ageing.

She also sought out genes that controlled the switch for maturation of T helper cells, maintaining just the right balance of T helpers — between Th1 cells that suppress allergic responses and Th2 cells that trigger them.

One of the hallmarks of cancer cells is they don't experience apoptosis and keep dividing out of control.

They are what they sound like: regulators that keep another group of cells, T helper cells, from proliferating out of control.

It is controlled, in part, by a series of channels on the surface of heart cells that regulate the movement of different ions into and out of the cells.

If we can boost the immune system and allow microglia to do their job and control brain tumor stem cells, it would be like removing the seed from the soil — stopping the tumor growth before it starts to get out of control.»

«We were fascinated to find that, without the influence of Myb, Treg cells would allow the immune response to spin out of control, resulting in severe inflammation pretty much everywhere — whether in the lungs, liver, intestine or skin,» she said.

But in multiple myeloma, plasma cells grow out of control in the bone marrow, crowding out healthy cells.

There have also been safety concerns confronting all hESC studies, including worries that the embryonic stem cells could proliferate out of control.

By controlling how the cells assemble, the researchers engineered films that carry out a wide range of motor functions.

Directly or indirectly, Holick points out, «the active form of vitamin D controls up to 200 different genes,» including ones responsible for cell proliferation, differentiation, and death.

Even after the cells were taken out of microgravity for up to 30 generations before being combined with the control strain, they maintained 72 per cent of their adaptive advantage, pointing to permanent mutations in the genes rather than merely a temporary adjustment.

But cancerous B cells are not only useless for fighting infection, they also grow out of control, leading to swollen lymph nodes, anemia, and frequent infections.

But sometimes things went wrong, cells multiplied out of control, and the result was cancer.

They also point out that the ability to use EroS to spur mating opens up a whole new level of experimental control in probing the cell biology of choanoflagellates.

In contrast, viruses that cause cancer, such as the human papillomavirus that is responsible for most cases of cervical cancer, disrupt a cell's genome, thereby triggering out - of - control growth.

CELLS GONE WILD Turning off the gene Apc in mouse intestinal cells in a culture dish spurs out - of - control cell growth (left panel, pCELLS GONE WILD Turning off the gene Apc in mouse intestinal cells in a culture dish spurs out - of - control cell growth (left panel, pcells in a culture dish spurs out - of - control cell growth (left panel, pink).

These genetic miscues can cause cells to grow out of control, evade the immune system, or fail to execute essential functions needed to maintain health.

Blackburn and UCSF psychologist Elissa Epel's work found that the most stressed - out women had shorter telomeres that translated into an extra decade or so of aging compared with their matched controls — showing that external stressors can throw a monkey wrench into the cell's molecular mechanics.

While cancer cells are immortal — their hallmark is wildly reproducing out of control — Hayflick discovered that normal cells have a limited life span.

In Parkinson's the pathways are thought to be out of balance, with interrupted motor cells causing the debilitating tremors and loss of movement control symptomatic of the disease.

Only when this process accelerates and spins out of control does it cause cell death, Snyder explains.

By measuring changes in the levels of proteins that control each cell death program and by observing the cells» physical changes, the team saw clearly that cocaine causes neuronal cell death through out - of - control autophagy.

Fisher's goal was to understand how to strike down the skin cells called melanocytes when they inexplicably go out of control and cause melanoma.

About 100,000 Americans have sickle cell disease, or one out of every 365 births in African - Americans, according to the Centers for Disease Control and Prevention.

«It turns out that the same signal — the so - called epidermal growth factor (EGF) pathway — control both the formation of pipes and beta cells through polarity changes.

Experiments conducted in mice and in human ALS cells reveal that when RIPK1 is out of control, it can spark axonal damage by setting off a chemical chain reaction that culminates in stripping the protective myelin off of axons and triggering axonal degeneration — the hallmark of ALS.

Like cells in all cancers, the B cells begin to grow out of control, creating tumors in the lymph nodes, spleen or other tissues.

The problem is that when RAS genes get mutated, that switch just won't turn off, and that leads to out of control cell growth.

In one of nature's mixed blessings, the mechanisms that work to heal cuts and wounds, rebuilding damaged cells, can also go out of control and cause cancer.

«Anandamide, an endocannabinoid, has been shown to have neuroprotective effects against seizures in basic research studies and this may turn out to be a key mechanism of seizure control,» explained Dale Deutsch, PhD, Professor of Biochemistry and Cell Biology and a faculty member of the Institute of Chemical Biology and Drug Discovery at Stony Brook University.

Fitch and co-authors Richard Wrangham of Harvard University and Adam Wilkins of Humboldt University in Berlin, who proposed their theory in July in Genetics, point out that these traits are controlled by so - called neural crest cells, which in vertebrate embryos form a neural tube along the spine.

In both acute and chronic myelogenous leukemia, immature white blood cells in the bone marrow multiply out of control.

When this happens, cell processes go out of control.

Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center — the nucleus — appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.

But if Arid1b is mutated, the blocks can not be degraded and the cell continues to grow, bypassing senescence and potentially growing out of control.

DNA mutations cause tumor cells to grow out of control, but they also generate variety that enables organisms to adapt to their environments and evolve.

The newly described nemertides attack tiny channels in cell walls that control the amount of sodium flowing in and out of the cell.

Manuela Martins - Green, a professor of cell biology at the University of California, Riverside, reports that two biological activities are out of control in chronic wound infections.

Enrich points out that «in the cell, cholesterol controls the trafficking of vesicles, which are responsible for transporting integrins to cell surface.

Zelboraf targets patients who test positive for a variant of the BRAF gene, another kinase that can go haywire and cause cells to grow out of control.

The NCI defines recurrence as cancer that returns after a patient has had no signs of out - of - control cell growth for at least a year.

«To really sort out if [stem] cells can treat these children, we need to do randomized, controlled trials that are well designed and well controlled, and that's what we intend to do,» says Kurtzberg, professor of pediatrics and pathology at Duke.

Knowing the origin of each cell and which genes control their normal function are the foundations for scientists to decipher the disease process and eventually to find out how to guide the cells to self - repair or even to build up a brand new organ using amended cells from the patients.»