Sentences with phrase «out of the nucleus»

It makes it possible for the nascent RNA to be carried out of the nucleus.

Typically it takes about a million times as much energy to get stuff out of a nucleus as it does to strip an electron from an atom.

Specifically, the Mount Sinai study was designed to test whether pharmacological compounds designed to block the function of XPO1 / CRM1 could stop disease progression in mouse models that exhibit some of the characteristics of MS. Researchers found that two chemical agents (called KPT - 276 and KPT - 350) prevented XPO1 / CRM1 from shuttling cargo out of the nucleus of nerve cells, which protected them from free radicals and structural damage.

This protein commandeers a host cell protein complex, human TREX, to stabilise and transport herpesvirus RNA out of the nucleus for translation into viral proteins.

The RNA strand is then moved out of the nucleus where enzyme - like organelles called ribosomes use it as a guide to synthesize chains of amino acids that form the desired protein.

Elucidating part of this response to the pretreatment, avicins were found to keep the nuclear transcription factor kB (NF - kB) protein out of the nucleus, where it stimulates the immune system and inflammation and can inhibit apoptosis if left turned on.

In 2015, Rothstein's team found out how a mutation in a gene — implicated in 40 percent of inherited ALS cases and 25 percent of inherited frontotemporal dementia cases — gums up transport in and out of the nucleus in neurons, ultimately shutting the cell down and leading to its death.

To make a protein, the sequence of genetic letters in each gene gets copied into matching strands of RNA, which then float out of the nucleus to guide the protein - making machinery of the cell.

FoxO is a transcription factor, and its phosphorylation causes it to be moved out of the nucleus preventing it from binding to its target genes.

Now, Fox01 phosphorylation leads to exclusion of Fox01 from the nucleus, so Fox01 is brought out of the nucleus.

Amazon undoubtedly took the wind out of Nucleus's sails with its announcement of the Echo Show.

Next, Grima looked at cell death in cultured neurons with a healthy or a mutant form of Huntingtin, or with a mutant form of Huntingtin that was treated with small amounts of an experimental drug called KPT - 350, one that prevents a nuclear export protein, Exportin - 1, from shuttling proteins and RNA out of the nucleus.

Moreover, they suggest, laboratory experiments with drugs designed to clear up these cellular «traffic jams» restored normal transport in and out of the nucleus and saved the cells.