Sentences with phrase «out of the nucleus in»

In 2015, Rothstein's team found out how a mutation in a gene — implicated in 40 percent of inherited ALS cases and 25 percent of inherited frontotemporal dementia cases — gums up transport in and out of the nucleus in neurons, ultimately shutting the cell down and leading to its death.

Not exact matches

The new elements, which are all man - made, fill out the seventh row of the periodic table, where elements are ranked according to their atomic number - the number of protons in their nucleus.

On the other hand, we read here several poems hardly distinguishable from the work of Second Isaiah; and we must conclude, therefore, that Isaiah 56 - 66 comes out of continuing Isaianic circles of prophetism surviving the sixth - century debacle, and had as its nucleus a small collection of Second Isaiah's oracles not incorporated in 40 - 55 and perhaps of somewhat later origin (see especially the three chapters, 60 - 62, and the Servant Song in 61:1 - 4).

DNA never leaves the nucleus of the cell; its molecular recipes are read out in the form of messenger RNA, which leaves the nucleus and enters the cytoplasm, where proteins are made.

If Comet ISON comes out the other side, Meech, Li, A'Hearn and countless others around the world will resume their vigil, looking for changes in the shape and composition of the nucleus.

Specifically, the Mount Sinai study was designed to test whether pharmacological compounds designed to block the function of XPO1 / CRM1 could stop disease progression in mouse models that exhibit some of the characteristics of MS. Researchers found that two chemical agents (called KPT - 276 and KPT - 350) prevented XPO1 / CRM1 from shuttling cargo out of the nucleus of nerve cells, which protected them from free radicals and structural damage.

«The argument that the nucleus is an endosymbiont (given by a number of authors) is just not borne out by our knowledge of the structure and function of the nucleus,» concludes Anthony Poole of Massey University in New Zealand.

The EPR authors described a source, such as a radioactive nucleus, that shot out pairs of particles with the same speed but in opposite directions.

Now, it turns out that the nuclei of much lighter elements, such as nickel, can also persist a little longer in their new shape.

For instance, ZBTB48 KO (knock - out) cells loose the expression of MTFP1 leading to defects in the mitochondrial network with mitochondria clustering around the nucleus instead of being widely spread throughout the cell.

As the scientists report today in Nature, about 80 % of the more than 120 events analyzed turned out to be light cosmic rays — protons or helium nuclei.

When Gillian Bates at Guy's Hospital, London and Stephen Davies at University College in London and their colleagues examined the brains of transgenic mice endowed with a DNA encoding 150 of these glutamine repeats, they found that the protein started out, at birth, in the cytoplasm of the animals» brain cells and then gradually migrated to cell nuclei and clumped there.

Comet Siding Spring's nucleus — a nugget of ice and rock measuring no more than half a kilometer (about 1/3 mile)-- is small, but the coma is expansive, stretching out a million kilometers (more than 600,000 miles) in every direction.

A few years ago, DARPA, which prides itself on promoting far - out projects, proposed spending $ 30 million on a «hafnium bomb,» a type of nuclear weapon intended to release energy from atomic nuclei without either fission or fusion, using an approach similar to how energy is extracted from electrons in a laser.

In order for the rat to take a step, the stimulus has to go not to the central nucleus but to the basal nucleus, and then out to the parts of the brain that are involved in active behavior.&raquIn order for the rat to take a step, the stimulus has to go not to the central nucleus but to the basal nucleus, and then out to the parts of the brain that are involved in active behavior.&raquin active behavior.»

Next, Grima looked at cell death in cultured neurons with a healthy or a mutant form of Huntingtin, or with a mutant form of Huntingtin that was treated with small amounts of an experimental drug called KPT - 350, one that prevents a nuclear export protein, Exportin - 1, from shuttling proteins and RNA out of the nucleus.

The way our genes are arrayed and move in the 3 - D space of the cell nucleus turns out to profoundly influence how they function, in both health and disease

Photons flit in and out of existence in the lead nuclei's strong electromagnetic fields.

Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center — the nucleus — appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.

Moreover, they suggest, laboratory experiments with drugs designed to clear up these cellular «traffic jams» restored normal transport in and out of the nucleus and saved the cells.

Now researchers at the University of Utah, The Florida State University, University College London and the University of Sydney in Australia report a way to extend that informational lifetime to more than 100 seconds by encoding an electron's spin onto the much longer - lived spin of an atomic nucleus, which can then be read out electronically.

Well you -LSB-'ve] got to have this design around it, what's the called blanket; and what the hope is, is that the neutron will go out and the blanket is made of some very thick steel - type material, and every so often, a neutron will just hit an atomic nucleus in the steel blanket and that hit will then make the steel hotter and that hot steel, and then you have, almost like in a car engine, you have some fluid, water could work, going through the steel, it takes the energy away, that water is hot, it goes and spins the turbine, okay that's great.

The signals from nuclei in a 1 state are 180 degrees out of phase from those in a 0 state, so can easily be told apart.

However, new research suggests that two of the most common types of active galactic nuclei do, in fact, exhibit fundamental physical differences in the way they consume matter and spit out energy.

«Our latest research findings support a newly emerging model of how the brain focuses attention on a particular task, using neurons in the thalamic reticular nucleus as a switchboard to control the amount of information the brain receives, limiting and filtering out sensory information that we don't want to pay attention to,» says senior study investigator and neuroscientist Michael Halassa, MD, PhD.

RNA was once thought to be a mere middleman, carrying genetic messages from the DNA in the nucleus out to cellular structures called ribosomes, where it directs the production of proteins.

Measurements carried out using the AGATA spectrometer has unravelled the details of neutron oscillations in the atomic nucleus and determined how many neutrons on the surface, or «skin», of the nucleus participate in unique vibrations known as pygmy resonances.

This object had an almost circular shape, and a light beam came out from its eastern part that crossed the sunspot to the south of the nucleus, producing a shadow on the penumbra that was lost in the large mass of faculae surrounding the eastern extreme of the sunspot.»

So from the myriad wobblings, researchers can in principle work out the relative locations of all the nuclei.

To work out why stimulation has this effect, Damiaan Denys and Martijn Figee at the Academic Medical Center in Amsterdam, the Netherlands, and colleagues recorded neural activity in people with electrodes implanted into a part of the brain called the nucleus accumbens.

One popular hypothesis, explained MacGibeny, was that a large number of viral genomes could saturate the silencing machinery in the nucleus, essentially «swamping out the neuron's defense system.»

«The heavy elements occur in modest amounts, adding to the case that the gas originated in the outskirts of the galaxies rather than being blasted out from the nucleus,» Keel said.

It turns out that many of the molecules that could be useful in replication float around in the cytoplasm, rather than in their workplace in the nucleus.

Specifically, researchers have learned that traffic in and out of the cells control center - the nucleus - breaks down in HD.

The authors next set out to see if this approach made sense for genetic regulation by running simulations of Mig1p finding its sites in the nucleus as either monomers or as clusters.

Scientists at the Pacific Northwest National Laboratory have added to the understanding of ERK with proof that ERK oscillates within cells; that is, it cycles continuously in and out of a cell's nucleus in response to cellular growth cues.

Just a few days ago, the ESA released this Hubble image of a pair of barred spiral galaxies some 350 million light years away in the process of merging, their two galactic nuclei still separated by a massive distance but throwing out clouds of hot gas and mid-formation stars.

«We were excited to find out that the current two subgenomes in pumpkin largely maintain the chromosome structures of the two progenitors despite sharing the same nucleus for at least three million years,» said Shan Wu, first author of the paper and BTI postdoc.

In the inherited form researched in the current study, this includes a deficiency of the protein progranulin, which is tied to the mislocalization of another crucial protein, TDP - 43, from the nucleus of the cell out to the cytoplasIn the inherited form researched in the current study, this includes a deficiency of the protein progranulin, which is tied to the mislocalization of another crucial protein, TDP - 43, from the nucleus of the cell out to the cytoplasin the current study, this includes a deficiency of the protein progranulin, which is tied to the mislocalization of another crucial protein, TDP - 43, from the nucleus of the cell out to the cytoplasm.

This process, known as gene expression, begins with transcription, in which a molecule called messenger RNA transfers the information in DNA out of the cell's nucleus and into the cytoplasm, where it is translated into amino acids that form proteins.

Watch The Love Competition and find out how researchers track activity in the area of the brain called the nucleus accumbens.

She is now one of the gang, part of a nucleus that never changes even when minor characters drift in and out at restaurants, cocktail parties, lazy afternoons at the Winslows» or at the beach, nights playing charades, sailing in my little sailboat, Johnny's ninth birthday, skinny - dipping in the ocean, or sitting under the stars listening to Verdi.

Shopping in Kata is a little spread out with the nucleus being around Kata's three - way intersection in the centre of Read More»

Much of the cosmic ray shower development involves the primary proton knocking out nucleons from a nucleus and these, in turn, do the same thing.