Sentences with phrase «out of the nucleus of»

Specifically, the Mount Sinai study was designed to test whether pharmacological compounds designed to block the function of XPO1 / CRM1 could stop disease progression in mouse models that exhibit some of the characteristics of MS. Researchers found that two chemical agents (called KPT - 276 and KPT - 350) prevented XPO1 / CRM1 from shuttling cargo out of the nucleus of nerve cells, which protected them from free radicals and structural damage.

Not exact matches

Maybe know all the basic versions, like «cloud brainstorming,» when you write down the nucleus of an idea and then branch out to all the potential mini clouds that relate to it.
They're hoping to find out what controls the size of the nucleus, the central compartment of a cell that contains the DNA, and other components of the cell as it develops into a many - celled organism.
The new elements, which are all man - made, fill out the seventh row of the periodic table, where elements are ranked according to their atomic number - the number of protons in their nucleus.
New evidence comes out to modify the structure of the atom (from a spherical particle to one of a nucleus and electrons orbiting it).
Mark's brief report of the instructions now becomes the nucleus of Matthew's second discourse, which, however, begins (10:5) on an exclusively Matthaean note: «These twelve Jesus sent out, charging them, «Go nowhere among the Gentiles, and enter no town of the Samaritans, but go rather to the lost sheep of the house of Israel.»»
Pagels (1984) points out that if the relative masses of protons and neutrons were different by a small fraction of 1 per cent, making the proton heavier than the neutron, hydrogen atoms would be unstable since the protons that constitute their nuclei would spontaneously decay into neutrons.
On the other hand, we read here several poems hardly distinguishable from the work of Second Isaiah; and we must conclude, therefore, that Isaiah 56 - 66 comes out of continuing Isaianic circles of prophetism surviving the sixth - century debacle, and had as its nucleus a small collection of Second Isaiah's oracles not incorporated in 40 - 55 and perhaps of somewhat later origin (see especially the three chapters, 60 - 62, and the Servant Song in 61:1 - 4).
DNA never leaves the nucleus of the cell; its molecular recipes are read out in the form of messenger RNA, which leaves the nucleus and enters the cytoplasm, where proteins are made.
If Comet ISON comes out the other side, Meech, Li, A'Hearn and countless others around the world will resume their vigil, looking for changes in the shape and composition of the nucleus.
To solve this, West proposed «therapeutic cloning» — taking the nucleus out of a patient's cell, transferring it into an egg cell to create a cloned embryo, then using that embryo to derive patient - matched stem - cell lines.
Instead, they have found that many of the rays consist of heavier nuclei, which curve more — making the job of figuring out their origin tougher.
«The argument that the nucleus is an endosymbiont (given by a number of authors) is just not borne out by our knowledge of the structure and function of the nucleus,» concludes Anthony Poole of Massey University in New Zealand.
The gamma rays knocked neutrons from one out of every 10 billion gold nuclei, making these nuclei so unstable that they decayed to platinum within several days.
The EPR authors described a source, such as a radioactive nucleus, that shot out pairs of particles with the same speed but in opposite directions.
Now, it turns out that the nuclei of much lighter elements, such as nickel, can also persist a little longer in their new shape.
To make sure she understood how nuclei, dendrites, and axons came together to form different types of brain cells, she pulled out her crochet hook and went to work.
For instance, ZBTB48 KO (knock - out) cells loose the expression of MTFP1 leading to defects in the mitochondrial network with mitochondria clustering around the nucleus instead of being widely spread throughout the cell.
Along with black holes, neutron stars are the result of stars collapsing under gravity once their fuel burns out, until their density is about the same as that of the nucleus of an atom, at which point the protons and electrons «melt» into pure neutrons.
When the gene for a glutamate transporter VGLUT2 was snipped out of the supramammillary nucleus, artificial stimulation had no effect on wake and sleep.
As the scientists report today in Nature, about 80 % of the more than 120 events analyzed turned out to be light cosmic rays — protons or helium nuclei.
RNA messages are copies of small snippets of DNA that move out of the cell nucleus to be converted into proteins.
Measurements of the space environment round it show that the water flowing out from the comet's nucleus forms a prominent atmosphere which interacts with the constant flow of ionised particles from the sun, the so - called solar wind.
When Gillian Bates at Guy's Hospital, London and Stephen Davies at University College in London and their colleagues examined the brains of transgenic mice endowed with a DNA encoding 150 of these glutamine repeats, they found that the protein started out, at birth, in the cytoplasm of the animals» brain cells and then gradually migrated to cell nuclei and clumped there.
Very rarely, one of the projectiles hits a nucleus head - on and forms a compound nucleus which flies out of the foil from the force of the collision.
Reminded by that of the Wells novel, Szilard imagined a neutron striking an atomic nucleus and thus knocking out two or more neutrons.
Comet Siding Spring's nucleus — a nugget of ice and rock measuring no more than half a kilometer (about 1/3 mile)-- is small, but the coma is expansive, stretching out a million kilometers (more than 600,000 miles) in every direction.
A few years ago, DARPA, which prides itself on promoting far - out projects, proposed spending $ 30 million on a «hafnium bomb,» a type of nuclear weapon intended to release energy from atomic nuclei without either fission or fusion, using an approach similar to how energy is extracted from electrons in a laser.
Normally, the fear response goes from the lateral nucleus to the central nucleus and then out of the amygdala.
In order for the rat to take a step, the stimulus has to go not to the central nucleus but to the basal nucleus, and then out to the parts of the brain that are involved in active behavior.»
To make Dolly, researchers took the nucleus out of a mature egg and replaced it with the nucleus from a cell of the ewe they wanted to clone; then they activated development with electrical pulses and implanted the embryo into a surrogate mother ewe.
WIMPs should also shove germanium nuclei out of position, knocking electrons into one another.
«Throughout the irradiated films, we saw individual chains of defects created by the collisions between the incident ions and nucleus that broke the perfect atomic order, causing the lattice to locally compress or stretch out,» said coauthor Lijun Wu, a materials scientist at Brookhaven who led the microscopy work.
Next, Grima looked at cell death in cultured neurons with a healthy or a mutant form of Huntingtin, or with a mutant form of Huntingtin that was treated with small amounts of an experimental drug called KPT - 350, one that prevents a nuclear export protein, Exportin - 1, from shuttling proteins and RNA out of the nucleus.
In 2015, Rothstein's team found out how a mutation in a gene — implicated in 40 percent of inherited ALS cases and 25 percent of inherited frontotemporal dementia cases — gums up transport in and out of the nucleus in neurons, ultimately shutting the cell down and leading to its death.
The way our genes are arrayed and move in the 3 - D space of the cell nucleus turns out to profoundly influence how they function, in both health and disease
Photons flit in and out of existence in the lead nuclei's strong electromagnetic fields.
Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center — the nucleus — appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.
Moreover, they suggest, laboratory experiments with drugs designed to clear up these cellular «traffic jams» restored normal transport in and out of the nucleus and saved the cells.
Now researchers at the University of Utah, The Florida State University, University College London and the University of Sydney in Australia report a way to extend that informational lifetime to more than 100 seconds by encoding an electron's spin onto the much longer - lived spin of an atomic nucleus, which can then be read out electronically.
Problems: sometimes the neutron goes out and hits a nucleus of the blanket and instead of just ringing it like a bell, it goes and one of the steel atoms absorb [s] the neutron; now this makes it different material, [it] makes it brittle, it makes it radioactive.
Well you -LSB-'ve] got to have this design around it, what's the called blanket; and what the hope is, is that the neutron will go out and the blanket is made of some very thick steel - type material, and every so often, a neutron will just hit an atomic nucleus in the steel blanket and that hit will then make the steel hotter and that hot steel, and then you have, almost like in a car engine, you have some fluid, water could work, going through the steel, it takes the energy away, that water is hot, it goes and spins the turbine, okay that's great.
The signals from nuclei in a 1 state are 180 degrees out of phase from those in a 0 state, so can easily be told apart.
However, new research suggests that two of the most common types of active galactic nuclei do, in fact, exhibit fundamental physical differences in the way they consume matter and spit out energy.
«Our latest research findings support a newly emerging model of how the brain focuses attention on a particular task, using neurons in the thalamic reticular nucleus as a switchboard to control the amount of information the brain receives, limiting and filtering out sensory information that we don't want to pay attention to,» says senior study investigator and neuroscientist Michael Halassa, MD, PhD.
But on the rare occasions when one does hit a nucleus of hydrogen or oxygen, the collision can spit out another subatomic particle, a muon.
RNA was once thought to be a mere middleman, carrying genetic messages from the DNA in the nucleus out to cellular structures called ribosomes, where it directs the production of proteins.
Northwestern researchers are analyzing tissue at the nano — as opposed to the micro — scale to root out cells whose nuclei have greatly expanded or otherwise show irregularities that could be signs of impending malignancy.
Systemic lupus erythematosus (SLE) is an immune reaction against material from the body's cellular nuclei leaking out of dying cells.
So each type of fissionable nucleus gives rise to myriad other nuclei that spit out antineutrinos.
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