Their content is optimized for genetic mapping in the Collaborative Cross and Diveristy
Outbred populations; for discriminating haplotypes from common laboratory strains and substrains; and for evaluating the ancestry of wild - caught mice.
Not exact matches
«Today, we have 700 to 750 individuals of the species,» says Martin, «but if action is not taken now, the white - headed duck could soon be
outbred by the invading ruddy duck, and wiped out in Spain, the only Western European country with a viable
population.»
This
outbreeding depression suggests that even low levels of admixture may have negative effects on fitness in the wild and that policies protecting hybridized
populations may need reconsideration.
Hybridization can reduce fitness by either introducing alleles to a
population that are not suited to the local environment (extrinsic
outbreeding depression) or disrupting co-adapted gene complexes (intrinsic
outbreeding depression)(Templeton 1986).
For example, previous reports have stated that genetic diversity in gerbil
populations is relatively low, but these reports are biased by divergence in the «
outbred»
population being studied.
The Diversity
Outbred (DO)
population is a heterozygous mouse stock that may be used for high - resolution mapping of genetic loci linked to disease susceptibility, drug resistance or behavioral phenotypes.
Molecular signatures of aging in the Diversity
Outbred mouse
population» by Petr Šimeček, Ph.D from The Jackson Laboratory, Bar Harbor, Maine, USA.
However, internal relatedness (IR) and adjusted IR (IRVD) values demonstrated that a number of individuals were the offspring of parents that were either more inbred or
outbred than the
population as a whole.