Because of the polygenic nature of hypertension, numerous rat models have been developed including selective bred homozygous hypertensive rat strains (e.g. spontaneously hypertensive rat [SHR] and Dahl salt sensitive [Dahl SS]-RRB- and
outbred strains (e.g. Sprague Dawley) to elucidate the desired hypertensive phenotype.
RML mice represent
an outbred strain that has been maintained at RML since 1937.
Not exact matches
Their content is optimized for genetic mapping in the Collaborative Cross and Diveristy
Outbred populations; for discriminating haplotypes from common laboratory
strains and substrains; and for evaluating the ancestry of wild - caught mice.
Rat models including
outbred Sprague - Dawley and Wistar rats are popular
strains to study obesity as they readily gain weight on high - fat diets.