Sentences with phrase «outcome than risking»

A bit of an odd incident, sure, but probably a better outcome than risking a penalty for holding someone up!

Not exact matches

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

Such risks and uncertainties include, but are not limited to: our ability to achieve our financial, strategic and operational plans or initiatives; our ability to predict and manage medical costs and price effectively and develop and maintain good relationships with physicians, hospitals and other health care providers; the impact of modifications to our operations and processes; our ability to identify potential strategic acquisitions or transactions and realize the expected benefits of such transactions, including with respect to the Merger; the substantial level of government regulation over our business and the potential effects of new laws or regulations or changes in existing laws or regulations; the outcome of litigation, regulatory audits, investigations, actions and / or guaranty fund assessments; uncertainties surrounding participation in government - sponsored programs such as Medicare; the effectiveness and security of our information technology and other business systems; unfavorable industry, economic or political conditions, including foreign currency movements; acts of war, terrorism, natural disasters or pandemics; our ability to obtain shareholder or regulatory approvals required for the Merger or the requirement to accept conditions that could reduce the anticipated benefits of the Merger as a condition to obtaining regulatory approvals; a longer time than anticipated to consummate the proposed Merger; problems regarding the successful integration of the businesses of Express Scripts and Cigna; unexpected costs regarding the proposed Merger; diversion of management's attention from ongoing business operations and opportunities during the pendency of the Merger; potential litigation associated with the proposed Merger; the ability to retain key personnel; the availability of financing, including relating to the proposed Merger; effects on the businesses as a result of uncertainty surrounding the proposed Merger; as well as more specific risks and uncertainties discussed in our most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.cigna.com as well as on Express Scripts» most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.express-scripts.com.

Kean added that the resistance coming from the B.C. government «leads us to the conclusion that we should protect the value that KML has, rather than risking billions of dollars on an outcome that is outside of our control.»

I agree Veldheer has played way better than Watson in the past but I think his risk of injury or just a massive decline due to age and injury history is a very likely outcome as well.

Flint and colleagues suggested that when midwives get to know the women for whom they provide care, interventions are minimised.22 The Albany midwifery practice, with an unselected population, has a rate for normal vaginal births of 77 %, with 35 % of women having a home birth.23 A review of care for women at low risk of complications has shown that continuity of midwifery care is generally associated with lower intervention rates than standard maternity care.24 Variation in normal birth rates between services (62 % -80 %), however, seems to be greater than outcome differences between «high continuity» and «traditional care» groups at the same unit.25 26 27 Use of epidural analgesia, for example, varies widely between Queen Charlotte's Hospital, London, and the North Staffordshire NHS Trust.

For healthy nulliparous women with a low risk pregnancy, the risk of an adverse perinatal outcome seems to be higher for planned births at home, and the intrapartum transfer rate is high in all settings other than an obstetric unit

The relative benefits and risks of birth in different settings have been widely debated in recent years.1 2 3 4 5 6 7 A problem when trying to evaluate the effect of birth setting on perinatal outcomes has been the use of actual place of birth rather than planned place of birth to define comparison groups.

It's disturbing that high risk moms with OBs have better outcomes than low risk moms with midwives.

When this 20 % risk of death is compared to the 0.02 % rate of cord prolapse during labor at homebirth that might have a better outcome if it happened in hospital, this means that a low risk woman has a 1000 times higher chance of having a life threatening complication either to her life or her fetus / newborns life at planned hospital birth, than if she plans to have an attended homebirth with a well - trained practitioner.

Women who are labelled as high - risk and whose births are managed by OB's have better outcomes than the low - risk women who give birth in the midwife - led part of the delivery ward.

For low - risk women who had never given birth before, home birth led to bad outcomes (such as encephalopathy or stillbirth) slightly less than 1 % of the time.

Rates of obstetrical intervention are high in U.S. hospitals, and we found large absolute differences in the risks of these interventions between planned out - of - hospital births and in - hospital births.38 In contrast, serious adverse fetal and neonatal outcomes are infrequent in all the birth settings we assessed, and the absolute differences in risk that we observed between planned birth locations were correspondingly small; for example, planned out - of - hospital births were associated with an excess of less than 1 fetal death per 1000 deliveries in multivariate and propensity - score - adjusted analyses.

An odds ratio of more than 1 indicates that the risk of the outcome is increased with planned out - of - hospital birth as compared with planned hospital birth.

For all low risk women, bootstrapped estimates showed that planned birth in settings other than an obstetric unit was associated with cost savings and considerable stochastic uncertainty surrounding adverse perinatal outcomes.

Nevertheless, «travel times greater than 20 minutes [to a healthcare facility] have been associated with increased risk of adverse neonatal outcomes, including mortality.»

A study reported in the BMJ found that women whose pregnancies were low - risk suffered far fewer severe negative outcomes from home than hospital births, especially after the first pregnancy.

So a team of Dutch researchers decided to test whether low risk women at the onset of labour with planned home birth have a higher rate of rare but severe outcomes (known as severe acute maternal morbidity or SAMM) than those with planned hospital births.

Multiple trials of low risk of bias contributed to each outcome, and there were precise estimates with no heterogeneity greater than 60 %.

Twelve of the included studies were judged at low risk of bias for incomplete outcome data on the basis that attrition rate was less than 20 % for all outcomes (other than satisfaction), or missing outcome data were balanced across groups (Begley 2011; Biro 2000; Flint 1989; Harvey 1996; Hicks 2003; Homer 2001; Kenny 1994; McLachlan 2012; North Stafford 2000; Tracy 2013; Turnbull 1996; Waldenstrom 2001).

And this inflammatory use of a «relative percentage risk» rather than relative risk or absolute risk... for example, even if assuming the writer's awkward data is valid, you can to look at infant living rates and see 99.6 % vs 98.4 %, which means there's only a 1.2 % higher risk of bad outcome from at - home birth than hospital.

Homebirth is in America as Homebirth in America does, yet the Homebirth advocates who are looking at the actually data are making excuses about the worse outcomes as they speculate that it is either due to the high risks births that were included, or because they must have been farther away from the hospital than just 5 minutes, or just ignoring the outcomes data and focusing on the low intervention data.

The actual data is suggestive of a low risk of bad outcomes for homebirthers, but they are clearly at higher risk than hospital birth!

Women in the planned home - birth group were significantly less likely than those who planned a midwife - attended hospital birth to have obstetric interventions (e.g., electronic fetal monitoring, relative risk [RR] 0.32, 95 % CI 0.29 — 0.36; assisted vaginal delivery, RR 0.41, 95 % 0.33 — 0.52) or adverse maternal outcomes (e.g., third - or fourth - degree perineal tear, RR 0.41, 95 % CI 0.28 — 0.59; postpartum hemorrhage, RR 0.62, 95 % CI 0.49 — 0.77).

The risk of all adverse maternal outcomes assessed was significantly lower among the women who planned a home birth than among those who planned a physician - attended hospital birth (Table 3).

«Pregnancy - associated melanoma is associated with higher death rates: Study sought to investigate histopathology, staging, risk factors, and outcomes of cutaneous melanoma in women younger than 50.»

Commenting on the study, Dr Kuehni said: «The study stands out from many others, in that it does not content itself with showing that putative risk factors and health outcome are associated (which means only that they occur more often together than would be expected by chance).

In other words, regardless of surgery timing, patients who require higher risk procedures, such as a major liver resection due to the presence of larger or multiple metastatic tumors or high - risk colorectal resections, have poorer outcomes than those who underwent more minor surgery.

The five year disease - free and overall survival rates for patients with high - risk malignant germ cell tumours remains less than 50 %, and so accurate diagnosis and monitoring is crucial to improving outcomes for patients.

In the article, Stamatina Iliodromiti from the University of Glasgow, UK, and colleagues found birth weight less than 25th or greater than 85th centile to be associated with greater risk of adverse outcomes compared with birth weight within these cutoffs, suggesting an expansion of the definition of «fetus at risk» beyond the less than 10th or greater than 90th centile range that is commonly used to trigger surveillance of fetal well - being and / or delivery.

Taking more than one antipsychotic can increase the risk for complications — including drug interactions, medication side effects, and metabolic disorders — without improving outcomes.

Although some research has suggested that the use of the anticoagulant warfarin for atrial fibrillation among patients with chronic kidney disease would increase the risk of death or stroke, a study that included more than 24,000 patients found a lower l - year risk of the combined outcomes of death, heart attack or stroke without a higher risk of bleeding, according to a study in the March 5 issue of JAMA.

She suggests that inappropriately designed fitness programs and services put users at increased risk of injury and adverse health outcomes rather than providing them with the tools to build a healthy lifestyle.

A new study demonstrates that negative outcomes have a greater influence on subsequent decisions than positive ones do: individuals are more likely to take a big risk following a loss than they would after a gain.

«The results of this study were of particular interest because more than half of the pregnant women with migraine experienced some type of adverse birth outcome, suggesting that these pregnancies should be considered high risk,» said study author Matthew S. Robbins, M.D., director of inpatient services at Montefiore Headache Center, chief of neurology at Jack D. Weiler Hospital of Montefiore, and associate professor of clinical neurology at Albert Einstein College of Medicine.

An analysis of clinical and institutional risk factors that may affect survival showed that medical centers performing fewer than five transplants per year had poorer outcomes than high - volume centers.

Of the approximately 4,000 who were identified as at risk for mental health problems and offered the ten - session group intervention during second grade, those who participated in a greater number of sessions showed significantly greater improvements in third - grade outcomes than did the at - risk students who participated in fewer sessions.

From detailed observations of the life courses of about 1000 New Zealanders, Dunedin has spun out more than 1200 papers on questions from the risk factors for antisocial behavior and the biological outcomes of stress to the long - term effects of cannabis use.

Of the factors examined that combine to create the County Health Rankings, the counties ranked lowest for poverty, measured as the number of children below the poverty line, had twice the relative risk of asthma as an outcome from PM2.5 exposure than those counties ranked highest (the largest difference).

While we know that other donor characteristics can influence the risk of the patient developing Graft versus Host disease or other complications, more research is needed to determine how important different donor factors are on outcomes other than patient survival.»

Whatever the outcome, these volunteers accepted personal risk, and in most cases did so to help others rather than themselves.

The work that garnered the honor, «An analysis of the risk and benefit of neoadjuvant chemotherapy among patients undergoing surgery for non-small cell lung cancer,» examined data from more than 134,000 patients in the National Cancer Database to assess the impact of neoadjuvant therapy on perioperative outcomes, as well as long - term survival.

Rick Kittles has been researching ancestry - informative genetic markers and how they can be utilizes in genomic studies on disease risk and outcomes for more than 20 years.

In another recent study published by the NEJM (3), researchers compared the health outcomes of patients that followed the very low sodium diet recommended by the FDA and AHA, consuming less than 3 g per day, and found that they had a higher risk of death or cardiovascular than those who consumed more than 7 grams per day:

Compared with potassium excretion of less than 1.5 grams per day, higher potassium excretion was associated with reduced risk of the composite outcome.

There are many studies that show that perinatal outcomes for low risk women in planned home birth are as good or better than those from planned hospital births.

Bioidentical Hormone Debate Safer More Efficacious Than Synthetic Kent Holtorf Postgraduate Medicine 2009 The Bioidentical Hormone Debate: Are Bioidentical Hormones (Estradiol, Estriol, and Progesterone) Safer or More Efficacious than Commonly Used Synthetic Versions in Hormone Replacement Therapy?Kent Holtorf, MD Conclusion: Physiological data and clinical outcomes demonstrate that bioidentical hormones are associated with lower risks, including the risk of breast cancer and cardiovascular disease, and are more efficacious than their synthetic and animalderived counterpaThan Synthetic Kent Holtorf Postgraduate Medicine 2009 The Bioidentical Hormone Debate: Are Bioidentical Hormones (Estradiol, Estriol, and Progesterone) Safer or More Efficacious than Commonly Used Synthetic Versions in Hormone Replacement Therapy?Kent Holtorf, MD Conclusion: Physiological data and clinical outcomes demonstrate that bioidentical hormones are associated with lower risks, including the risk of breast cancer and cardiovascular disease, and are more efficacious than their synthetic and animalderived counterpathan Commonly Used Synthetic Versions in Hormone Replacement Therapy?Kent Holtorf, MD Conclusion: Physiological data and clinical outcomes demonstrate that bioidentical hormones are associated with lower risks, including the risk of breast cancer and cardiovascular disease, and are more efficacious than their synthetic and animalderived counterpathan their synthetic and animalderived counterparts.

So, in other words, if Americans would just get in the recommended amounts of fruits and veggies, it would not only provide carotenoids, but more than enough of all of them to produce the beneficial health outcomes, including reduced risks of cancer.

The World Health Organization recommended less than 10 % of calories from added sugar based on its assessment of higher consumption and adverse health outcomes.4 With the evidence of higher added sugar consumption and adverse health outcomes accumulating, the American Heart Association recommended that total calories from added sugar should be less than 100 calories / d for most women and less than 150 calories / d for most men.5 Our analysis suggests that participants who consumed greater than or equal to 10 % but less than 25 % of calories from added sugar, the level below the Institute of Medicine recommendation and above the World Health Organization / American Heart Association recommendation, had a 30 % higher risk of CVD mortality; for those who consumed 25 % or more of calories from added sugar, the relative risk was nearly tripled (fully adjusted HR, 2.75).

If you are afraid to take the risk, don't let the fear hold you back, but just prepare and accept the best of the outcomes, rather than the worst.