Sentences with phrase «outcomes data in the study»

This may have been partly due to limitations in outcomes data in the study, but even if the intervention could be targeted solely at high - risk children it would only be cost - effective if society was willing to pay more than $ 750 000 (2004 prices) per case of conduct disorder averted (Foster and Jones, 2006, 2007; Foster, 2010).

Not exact matches

But Amgen's rivals in the space, Sanofi and Regeneron (which have their own PCSK9 blocking medicine called Praluent), announced that an independent data monitoring committee hasn't seen enough significant evidence in a huge, 18,000 - patient cardiovascular outcomes trial to stop the study early.

The Abacus study also asked those who voted in the 2015 Canadian General Election to rank a ballot that included the main political parties and generated data for 11 regions to estimate, with increased precision, the outcome of the Canadian election had it been run under different electoral systems.

The aim of our study was to determine firstly, whether a retrospective linked data study was a viable alternative to such a design using routinely collected data in one Australian state and secondly, to report on the outcomes and interventions for women (and their babies) who planned to give birth in a hospital labour ward, birth centre or at home.

Our use of observational data reflects the existing literature on lactation and maternal health; apart from a single randomized trial examining the effect of exclusive lactation duration on maternal weight loss, 48 there are no published studies of maternal health outcomes in randomized trials of breastfeeding.

We also calculated outcome rates before reclassification to determine the effect of misclassification in standard vital statistics data, including prior U.S. studies on place of birth.

For example, the fact that 27 transfer patients are listed as having a physician as their planned birth attendant is most likely due to errors in birth - certificate completion; data are currently lacking to inform the degree of misclassification related to this and others factors that affect the study outcomes.

Of note, our models may underestimate the true maternal costs of suboptimal breastfeeding; we modeled the effects of lactation on only five maternal health conditions despite data linking lactation with other maternal health outcomes.46 In addition, women in our model could not develop type 2 diabetes mellitus, hypertension, or MI before age 35 years, although these conditions are becoming increasingly prevalent among young adults.47 Although some studies have found an association between lactation and rates of postmenopausal diabetes22, 23 and cardiovascular disease, 10 we conservatively limited the duration of lactation's effect on both diabetes and MIn addition, women in our model could not develop type 2 diabetes mellitus, hypertension, or MI before age 35 years, although these conditions are becoming increasingly prevalent among young adults.47 Although some studies have found an association between lactation and rates of postmenopausal diabetes22, 23 and cardiovascular disease, 10 we conservatively limited the duration of lactation's effect on both diabetes and Min our model could not develop type 2 diabetes mellitus, hypertension, or MI before age 35 years, although these conditions are becoming increasingly prevalent among young adults.47 Although some studies have found an association between lactation and rates of postmenopausal diabetes22, 23 and cardiovascular disease, 10 we conservatively limited the duration of lactation's effect on both diabetes and MI.

Of the 31 new studies included in this update, 21 provided data for one or more of the primary outcomes.

Incorporating the vast majority of comparative birth studies to date in a contemporary appraisal of elective cesarean delivery in healthy women is flawed, primarily because their data includes outcomes from emergency surgeries and elective surgeries in women (and babies) with pre-existing medical conditions.

For the purposes of this economic evaluation, the forms were initially used in a related study funded by the National Institute of Health Research (NIHR) research for patient benefit programme «assessing the impact of a new birth centre on choice and outcome of maternity care in an inner city area,» which will be reported in full elsewhere, comparing the costs of care in a free standing midwifery unit with care in an obstetric unit in the same trust.16 The data collected included details of staffing levels, treatments, surgeries, diagnostic imaging tests, scans, drugs, and other resource inputs associated with each stage of the pathway through intrapartum and after birth care.

Limitations of this study included those inherent in the included studies, self - selection of women for home birth, and insufficient data for some outcomes.

The study, published in the Journal of Midwifery & Women's Health on Thursday, looked at the home birth outcomes for roughly 17,000 women as recorded in the Midwives Alliance of North America data collection system between 2004 and 2009.

Although in all studies multiple pregnancies or births (women or their infants) were eligible for inclusion, no outcome data were reported separately for multiples in the published reports.

Measures of maternal satisfaction were reported in one study of 15 women, but there were insufficient data to draw any conclusions; no other secondary outcomes were reported for women with a multiple pregnancy in either study.

In these studies, investigators made an attempt to blind outcome assessors, however, because women knew their group allocation, and all data were self - reported, the group allocation could have been revealed during data collection.

Given the heterogeneity in the choice of outcome measures routinely collected and reported in randomised evaluations of models of maternity care, a core (minimum) data set, such as that by Devane 2007, and a validated measure of maternal quality of life and well being would be useful not only within multi-centre trials and for comparisons between trials, but might also be a significant step in facilitating useful meta - analyses of similar studies.

Observational studies of prolonged (> 6 months) exclusive versus mixed breastfeeding, developed countries Infant outcomes No differences in gains in weight and length were reported in the first 12 months of life in an observational study of infants who were exclusively breastfed beyond six months versus those exclusively breastfed for less than six months and mixed breastfed thereafter (actual data not reported).

Measures ofmaternal satisfaction were reported in one study of 15 women, but there were insufficient data to draw any conclusions; no other secondary outcomes were reported for women with multiple births in either study.

«For this large cohort of women who planned midwife - led home births in the United States, outcomes are congruent with the best available data from population - based, observational studies that evaluated outcomes by intended place of birth and perinatal risk factors.

Moreover, data for exposures in almost all studies were based only on maternal recall, sometimes some years after the exposures, although studies have shown that mothers remember breastfeeding durations many years after breastfeeding has stopped.55 - 57 Furthermore, research shows that mothers of sick children sometimes remember early exposures of their children in greater detail compared with mothers of healthy children, especially when the exposures are publicly perceived to be associated with the outcome studied.

To be included in this critical review, studies had to be U.S. - based randomized trials evaluating a breastfeeding promotion intervention, reporting breastfeeding outcome data, enrolling primarily minority participants, and conducting analyses by intention to treat.

Studies had to be case control for the purpose of the statistical analysis; have breastfeeding as a measured exposure and leukemia as a measured outcome; include data on breastfeeding duration in months, including but not limited to, 6 months or more (where relevant data were unavailable in the publication, the authors of the studies were contacted); and been published in peer - reviewed journals with full text available in EStudies had to be case control for the purpose of the statistical analysis; have breastfeeding as a measured exposure and leukemia as a measured outcome; include data on breastfeeding duration in months, including but not limited to, 6 months or more (where relevant data were unavailable in the publication, the authors of the studies were contacted); and been published in peer - reviewed journals with full text available in Estudies were contacted); and been published in peer - reviewed journals with full text available in English.

Using data from the Danish National Birth Cohort in Denmark, researchers in the University of Adelaide's Robinson Research Institute studied the outcomes of 368 women who were on antidepressants prior to becoming pregnant.

Study Selection To be included in the meta - analyses, studies had to be case control; include breastfeeding as a measured exposure and leukemia as a measured outcome; include data on breastfeeding duration in months; and be published in a peer - reviewed journal with full text available in English.

To be included in the meta - analyses, studies had to be case control; include breastfeeding as a measured exposure and leukemia as a measured outcome; include data on breastfeeding duration in months; and be published in a peer - reviewed journal with full text available in English.

Design study of outcomes by birth place in states where mandatory data collection already exists

Loss to follow - up was a particular problem in studies where women were recruited in the antenatal period and, as we have described above, we have not included any outcome data from studies that were otherwise eligible for inclusion in the review because of high levels of attrition for all outcomes.

For all outcomes we have ordered studies in terms of weight, where a sufficient number of studies contributed data, we have generated funnel plots.

It was not possible to analyse the following outcomes, either because data were not reported by any studies or they were reported in a way that did not allow extraction of the necessary data for meta - analysis, or losses and exclusions were more than 20 % of the randomised participants.

Although this study was not powered to assess the impact of mother — infant sleep proximity on long - term breastfeeding outcomes, these indicative data suggested that such a trial was warranted; this trial is now underway and due to report in 2010.

In the other seven studies, the relationship between the recipients of the intervention and the source of the outcome data varied.

In 66 of the 73 studies outcome data were collected from the women who had received the intervention.

In a study of national data on colon surgery, Johns Hopkins researchers found that while patients who undergo either minimally invasive laparoscopic surgery or the high - tech robotic approach have similar outcomes, robotic surgery is significantly more expensive.

Researchers studied data from 2,279 heart failure patients in a trial called Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF - ACTION).

And no empirical data has tied researchers» financial interests in a study to negative outcomes for patients.

The Columbia researchers used data from peer - reviewed studies and health and social sciences databases to assess the link between menarche and various negative sexual and reproductive health outcomes in adolescence.

The study analyzed data regarding surgical outcomes — complications, serious complications, and mortality — in over 345,000 patients treated between 2009 and 2013 at academic hospitals throughout the United States.

The data safety monitoring board of the trial, as mandated by the study protocol, continues to monitor outcomes in patients with a Recurrence Score of 11 to 25 randomized to chemo - endocrine therapy or endocrine therapy alone.

In this study, researchers reviewed Spine Patient Outcomes Research Trial (SPORT) data for 105 patients, age 80 and older, and 1,130 patients younger than age 80 with lumbar stenosis alone or combined with degenerative spondylolisthesis.

The first, by researchers based in the UK, Europe and USA, examined data from observational studies and clinical trials (an umbrella review) to summarisze health outcomes associated with vitamin D levels, both naturally circulating and as a result of taking supplements.

In a recent study analyzing the results of a global, multicenter trial, data show a 91 percent probability of favorable stroke outcome if patients» blood flow was restored within 150 minutes of stroke.

Scientists still have to analyze the data collected to learn more about how well the drug, called TKM - Ebola - Guinea, was tolerated and what specific effects it had on disease outcomes, says Peter Horby of the University of Oxford in the United Kingdom, who headed the study.

Although transplantations were performed in the 1960s, the study began gathering data from 1987 when the United Network for Organ Sharing (UNOS) first established measures for evaluating transplantation outcomes.

Their analysis included data from the Coronary Artery Risk Development in Young Adults (CARDIA) study, which contained repeated assessments of marijuana use and kidney outcomes.

The New York Times published a study in September that involved giving four different research teams the same raw data, and asked them to predict the outcome of the election.

• An environmental epidemiological study should be performed to determine whether an association exists between health outcomes data and water quality in private drinking wells in communities with and without hydraulic fracturing.

In a new study in JAMA Neurology, a team led by Dr. Shadi Yaghi, assistant professor of neurology, analyzed data from 10 stroke centers across the country between 2009 and 2014 to investigate the treatment and outcome of sICIn a new study in JAMA Neurology, a team led by Dr. Shadi Yaghi, assistant professor of neurology, analyzed data from 10 stroke centers across the country between 2009 and 2014 to investigate the treatment and outcome of sICin JAMA Neurology, a team led by Dr. Shadi Yaghi, assistant professor of neurology, analyzed data from 10 stroke centers across the country between 2009 and 2014 to investigate the treatment and outcome of sICH.

Potential cardioprotection was based on generally supportive data on lipid levels in intermediate outcome clinical trials, trials in nonhuman primates, and a large body of observational studies suggesting a 40 % to 50 % reduction in risk among users of either estrogen alone or, less frequently, combined estrogen and progestin.2 - 5 Hip fracture was designated as a secondary outcome, supported by observational data as well as clinical trials showing benefit for bone mineral density.6, 7 Invasive breast cancer was designated as a primary adverse outcome based on observational data.3, 8 Additional clinical outcomes chosen as secondary outcomes that may plausibly be affected by hormone therapy include other cardiovascular diseases; endometrial, colorectal, and other cancers; and other fractures.3, 6,9

To identify methodological categories, the outcome of each paper was classified according to a set of binary variables: 1 - outcome measured on biological material; 2 - outcome measured on human material; 3 - outcome exclusively behavioural (measures of behaviours and interactions between individuals, which in studies on people included surveys, interviews and social and economic data); 4 - outcome exclusively non-behavioural (physical, chemical and other measurable parameters including weight, height, death, presence / absence, number of individuals, etc...).