The researchers call for more targeted studies to assess the clinical
outcomes of patients who test positive for metal sensitization.
If this is true, then immunocheckpoint blockade combination with EGFR tyrosine kinase inhibitors is a major path towards improving
outcome of patients who have EGFR - mutant non-small-cell lung cancer.»
Not exact matches
Research has shown that medical
patients who develop emotional health problems cost more to treat and respond less well to treatment; as a result, says Ahern, «it behooves the medical system to do a better job in detection and treatment
of behavioral health because it drives
outcomes and drives the costs.»
But they've been hampered by somewhat skeptical physicians
who still aren't sure that the drugs are worth their price (their topline costs are around $ 14,000 per treatment course); part
of the problem is that it's unclear whether or not those dramatic cholesterol reductions actually translate into broader health
outcomes like a reduced risk
of stroke or heart attack in heart disease
patients.
REDUCE - IT is the first multinational cardiovascular
outcomes study evaluating the effect
of prescription pure EPA therapy, or any triglyceride - lowering therapy, as an add - on to statins in
patients with high cardiovascular risk
who, despite stable statin therapy, have elevated triglyceride levels (150 - 499 mg / dL).
Novartis (nvs) chief Joe Jiminez has been touting a pricing model that incorporates drugs» real - world
outcomes for years, stressing the importance
of placing
patients before profits; Regeneron (regn) head honcho Len Schliefer had some tough words for fellow panelists from Eli Lilly (lly) and Pfizer (pfe)(
who argued that media reports about their own continued reliance on price increases to drive revenues is misleading) during Forbes» event.
To illustrate the issue, over the past 20 years, the cost
of a new drug per year
of a
patient's life has risen from $ 50,000 to $ 250,000 after adjusting for inflation, according to Peter Bach, director
of the Center for Health Policy and
Outcomes at Memorial Sloan Kettering,
who also spoke at the conference.
Once she can start aggregating data from her
patients with data from other doctors
who are using the app, she will have a huge number
of data points that she can use to track everything from the efficacy
of the surgery in certain
patient populations, to which doctors might get the best
outcomes.
Jain elaborated on those successes in an article in the Journal
of the American Medical Association last year, noting the efficiencies lead to better
outcomes for
patients,
who can more reliably receive routine medical care and stay out
of emergency rooms; doctors,
who can more easily manage
patients» chronic conditions; and cost - savings for the broader medical system, as managing chronic disease is substantially cheaper than repeated ER visits.
Like all parallel medical services, it falls to the
patient to figure out
who is legitimately skilled and
who is not: EXCEPT, most women having babies are in their twenties and early thirties and I personally didn't have the kind
of life - experience necessary to question whether or not my government would provide me with sub par care and just assumed that if the government was paying, it must be safe, and the midwifery community capitalizes on this by running advertisements (which OB / GYN are not permitted to do) advertising themselves as being less interventionist, less c - section (no shit, Sherlock, but you'd have to read between the lines to understand why), and better
outcomes.
And secondly, if doctors are corrupted by making money, as they are in my experience, and doctors
who in theory have a professional ethic
of putting the
patient first, well for Christ's sake, businessmen are going to be infinitely more corrupted and will be much more concerned about cutting corners and squeezing as much money out
of the system as possible without any deep, ethical concern for the
outcome.»
Erie County and each Mall partner are teaming up with the University at Buffalo's School
of Public Health to conduct long - term studies
of the health
outcomes and health care utilization
of patients who visit the Health Mall.
The National Confidential Enquiry into
Patient Outcome and Death (NCEPOD) investigated the care given to 820
patients over 80 years
of age,
who died within 30 days
of surgery being performed on them.
In the new study,
patients receiving angioplasty with the new stents had a 47 percent higher risk
of one
of the
outcomes identified as a primary endpoint in the study: death, heart attack and subsequent procedure to clear blocked arteries, as compared to
patients who received bypass.
«
Patients undergoing surgery for a hip fracture were older and had more comorbidities than patients who underwent an elective THR, and these differences accounted for some of the difference in outcomes between these groups,» the author
Patients undergoing surgery for a hip fracture were older and had more comorbidities than
patients who underwent an elective THR, and these differences accounted for some of the difference in outcomes between these groups,» the author
patients who underwent an elective THR, and these differences accounted for some
of the difference in
outcomes between these groups,» the authors write.
She found that antihistamines, like those found in Unisom and Benadryl, were taken by more than 50 percent
of HG
patients who experienced adverse
outcomes.
Researchers at Dana - Farber / Boston Children's Cancer and Blood Disorders Center report promising
outcomes from a clinical trial with
patients with a rare form
of bone marrow failure
who received a hematopoietic stem cell transplant (HSCT) after pre-treatment with immunosuppressive drugs only.
The data suggest that this immunosuppression - only approach could benefit
patients with DC — and, perhaps, other bone marrow failure syndromes —
who are at high risk
of poor transplant
outcomes because they can not tolerate the toxicity
of conventional or even reduced - intensity conditioning.
We identified
patients with mutations that predict phenomenal
outcomes in the disease; this is a group
of women with endometrial cancer
who won't need the financial, physical or emotional toll
of chemotherapy at all — they're
patients who are probably cured by surgery alone.
«In summary, these encouraging data build upon the real success
of our translational efforts in myeloma over the last decade, and provide exciting new options with the real promise
of improving
patient outcome,» said Richardson,
who is also the R.J. Corman professor at Harvard Medical School.
Although a bad
outcome was possible without the gene expression pattern,
patients with the genetic signature were found to survive for less time than those
who didn't have it, they wrote in the 9 December online edition
of Nature Genetics.
In a study
of national data on colon surgery, Johns Hopkins researchers found that while
patients who undergo either minimally invasive laparoscopic surgery or the high - tech robotic approach have similar
outcomes, robotic surgery is significantly more expensive.
In other words, regardless
of surgery timing,
patients who require higher risk procedures, such as a major liver resection due to the presence
of larger or multiple metastatic tumors or high - risk colorectal resections, have poorer
outcomes than those
who underwent more minor surgery.
«We wanted to test the hypothesis that both the extent
of the liver resection and the location or type
of colorectal resection influence the overall risk and
patient outcomes associated with these operations,» says the article's first author, Christopher Shubert, M.D.,
who is also a surgeon and Kern Scholar at Mayo Clinic.
Jennifer A. Woyach, M.D.,
of Ohio State University, Columbus, and coauthors described the characteristics
of patients who discontinued ibrutinib therapy and their
outcomes in a group
of 308
patients participating in four trials at a single institution.
Researchers from Massachusetts Eye and Ear / Harvard Medical School have found that
patients who were prescribed corticosteroids as part
of treatment for Lyme disease - associated facial paralysis had worse long - term
outcomes of regaining facial function than those
who were prescribed antibiotic therapy alone.
A large study
of 108,711
patients who had cardiac surgery in Ontario, Canada, sought to identify risk factors for long - term stroke after surgery to improve
outcomes for
patients.
Using validated, standardized tests for measuring the
outcomes of patients with facial paralysis, experts
who were naïve to the treatment
patients received studied video documentation
of a standardized sequence
of facial expressions for each
patient.
Patients who didn't seek follow - up care within a month received the lowest rate of care and had the worst health outcomes — demonstrating the need to improve follow - up with high risk chest pain patients after they're discharged from the emergency room,
Patients who didn't seek follow - up care within a month received the lowest rate
of care and had the worst health
outcomes — demonstrating the need to improve follow - up with high risk chest pain
patients after they're discharged from the emergency room,
patients after they're discharged from the emergency room, Ko said.
«We're trying to find better prognostic indicators
of outcomes so that only
patients who will benefit from additional therapy receive it.»
«
Patients with head injuries do better when treated by trauma centers, even if it means bypassing other hospitals: Study shows a major opportunity to improve outcomes for the half of severe head injury patients who are brought to hospitals without trauma centers
Patients with head injuries do better when treated by trauma centers, even if it means bypassing other hospitals: Study shows a major opportunity to improve
outcomes for the half
of severe head injury
patients who are brought to hospitals without trauma centers
patients who are brought to hospitals without trauma centers.»
Averaged over a four - year follow - up period, operatively treated
patients at least 80 years
of age, had significantly greater improvement in all primary and secondary
outcome measures compared with
patients at least 80 years
of age
who received nonsurgical treatment.
Patients who sustain severe head injuries tend to have better
outcomes if they are taken to a designated trauma center, but 44 percent
of them are first taken to hospitals without these specialized care capabilities, according to new research from the Perelman School
of Medicine at the University
of Pennsylvania.
The researchers next will turn to analyzing the presence
of myoferlin in samples from numerous human tumor types available in an Ohio State tissue bank, which will allow them to compare protein levels in tumors to clinical
outcomes for the
patients who provided the samples.
An analysis
of patients treated for lumbar stenosis and degenerative spondylolisthesis,
who were enrolled in the Spine
Patient Outcomes Research Trial (SPORT), was performed.
The odds
of a good stroke
outcome were 75 % greater for
patients given alteplase within 3 hours
of initial stroke symptoms, compared with those
who did not receive the drug; for those given the drug between 3 and 4 · 5 hours post-stroke there was a 26 % increased chance
of a good
outcome; while for those with a delay
of more than 4 · 5 hours in receiving treatment, there was just a 15 %, not statistically significant, increase in the chance
of a good recovery.
In the JBJS study, researchers reviewed the BMI, comorbidities, complications,
outcomes and cost
of care
of 8,129
patients who had undergone 6,475 primary TKRs and 1,654 revision TKRs at a major medical center between Jan. 1, 2000 and Sept. 30, 2008.
As we are now able to focus our efforts on improving the overall
patient experience and reducing the risk
of relapse, the leading cause
of death after transplant, we have greatly improved long - term survival
outcomes for
patients who before might not have had another treatment option.»
In the present study, performed by Prof. Latzer
who is also the director
of the Eating Disorders Clinic at Rambam Medical Center, the research student Adit Zohr - Beja, and Dr. Eitan Gur from the Eating Disorders Department, Sheba Medical Center, Tel Hashomer, the researchers sought to examine claims concerning the ineffectiveness
of involuntary hospitalization and examined whether there is a difference in
outcome between
patients in extreme condition
who were forcibly hospitalized and those
who were hospitalized willingly.
Researchers also contend that transplant
outcomes can be further improved by identifying
patients who are at high risk for certain complications, such as cognitive decline, or by employing post-transplant treatments to reduce their risk
of relapse.
Christiani would like to see an experiment that compares the survival
of patients administered large doses
of the vitamin during treatment and follow - up periods against the
outcomes of people
who rely on diet and conventional therapy alone.
But little information is available about the long - term
outcomes of young
patients, especially women,
who survive cardiovascular events.
In the study, analysis
of patient samples demonstrated that high LSC17 scores meant poor
outcomes with current standard treatment, even for
patients who had undergone allogeneic stem cell transplantation.
«Not enough emphasis has been placed on assessing delirium severity in the ICU because there is a lack
of understanding
of how significant
outcomes of delirium are for
patients,» said IU School
of Medicine, IU Center for Aging Research, and Regenstrief Institute faculty member Babar A. Khan, MD,
who led the study.
The three - quarters
of patients who are diagnosed early have much better
outcomes than those whose disease is diagnosed late.
Patients who underwent open - heart surgery in the afternoon experienced better health outcomes compared to those who got operated on in the morning, study authors found after six years of observing nearly 600 patients who underwent heart valve repl
Patients who underwent open - heart surgery in the afternoon experienced better health
outcomes compared to those
who got operated on in the morning, study authors found after six years
of observing nearly 600
patients who underwent heart valve repl
patients who underwent heart valve replacement.
Steve: You — in the cystic fibrosis section
of the book — you profile a doctor
who is explaining to one
of his
patients that the difference between feeling good 99.5 and 99.95 percent
of the time on any given day, works out to completely different
outcomes over the course
of a year.
«The majority
of cancer
patients we work with are excited to participate in clinical trials that could benefit future
patient outcomes down the line,» says co-senior author Bryan Allen,
who led the clinical side
of the study.
Writing in a linked Comment, Professor Philip Cowen, MRC Clinical Scientist, University
of Oxford, Oxford, UK, says: «The key observation that might eventually justify the use
of a drug like psilocybin in treatment - resistant depression is demonstration
of sustained benefit in
patients who previously have experienced years
of symptoms despite conventional treatments, which makes longer - term
outcomes particularly important.
President
of ESTRO, Professor Vincenzo Valentini, a radiation oncologist at the Policlinico Universitario A. Gemelli, Rome, Italy, said: «This study not only shows a better
outcome for the women treated with IMRT, but has an additional value in defining the selection criteria for providing treatment to those
patients who will benefit from new frontline technologies.