The first immunogens are those similar to the trimer
outer Envelope protein of native HIV.
Not exact matches
Shukla hopes to further develop the nanoparticles to work against HIV, which like HSV - 2 also has positively charged
proteins embedded in its
outer envelope.
The tetrapod - shaped zinc - oxide nanoparticles, called ZOTEN, have negatively charged surfaces that attract the HSV - 2 virus, which has positively charged
proteins on its
outer envelope.
As the body produces antibodies to target the
outer HIV
envelope protein, this
protein changes, thwarting the circulating antibodies» ability to neutralize it.
Subjecting N. gonorrhoeae to the phenotypic microarray screening method for the first time, Sikora's team focused on seven
proteins from the bacteria's cell
envelope, which consists of the
outer membrane, the cell wall and the inner membrane.
Alexander Pletnev and colleagues at the National Institute of Allergy and Infectious Diseases in Bethesda, Maryland, and the nearby Walter Reed Army Institute of Research have taken two genes from West Nile virus that encode
proteins that form the
outer envelope of the virus, and spliced them into the dengue virus type 4, which does not attack the central nervous system.
Two accessory
proteins orchestrate the Cpx - TCS: The periplasmic
protein CpxP inhibits the Cpx - TCS in unstressed cells and detects misfolded
envelope proteins; the
outer membrane lipoprotein NlpE activates the Cpx - TCS during biofilm formation.
One of the viral genes, env, specifies a
protein that forms the viral
envelope, the
outer covering of the virus that interacts with a target receptor on the surface of lung cells.