Not exact matches
The
cells of the
outer layer will later give rise to the extraembryonic membranes and the placenta after the blastocyst implants in the wall of the uterus, while the embryo itself develops from the inner
cell mass.
The differentiation of the
outer layer of blastocyst
cells from the inner
cell mass is already underway by the 8 -
cell stage.
Figure 1: The blastocyst is a hollow sphere made of approximately 150
cells and contains three distinct areas: the trophoblast, which is the surrounding
outer layer that contains the trophoblast stem
cells and later becomes the placenta, the blastocoel, which is a fluid - filled cavity within the blastocyst, and the inner
cell mass, also known as the embryoblast, which can become the embryo proper, or fetus, and is where human embryonic stem
cells are isolated from.
The blastocyst is a hollow sphere made of approximately 150
cells and contains three distinct areas: the trophoblast, which is the surrounding
outer layer that later becomes the placenta, the blastocoel, which is a fluid - filled cavity within the blastocyst, and the inner
cell mass, also known as the embryoblast, which can become the embryo proper, or fetus, and is where hESCs are isolated from.
By activating a gene called Ras in
cells bathed in a very specific culture medium, scientists were able to cause embryonic stem
cells — which originate from the inner
cell mass of the blastocyst — to become more like the trophoblastic stem
cells that give rise to the placenta from the
outer portion of the blastocyst.