Sentences with phrase «outer membrane proteins»

Bioinformatics support the possible triggering of autoimmune thyroid diseases by Yersinia enterocolitica outer membrane proteins homologous to the human thyrotropin receptor.

We identified genomic «hotspots» of homologous recombination that include regions containing outer membrane proteins, the lipopolysaccharide (LPS) region and Dot / Icm effectors, which provide interesting clues to the selection pressures faced by L. pneumophila.

They wanted to know exactly how these subunits work together to insert the outer membrane proteins into the outer membrane or cell wall.

«In Human mitochondria, a similar complex called sorting and assembly machinery complex (SAM) is responsible for building the outer membrane proteins in the outer membrane of mitochondria.

«Dysfunction of mitochondria outer membrane proteins are linked to disorders such as diabetes, Parkinsons and other neurodegenerative diseases, so we hope that this work may also help us to better understand these human diseases too.»

Outer membrane proteins have crucial physiological and structural functions, among them nutrient acquisition, secretion, signal transduction, outer membrane biogenesis, and motility.

We found that the five subunits form a ring structure and work together to perform outer membrane protein insertion using a novel rotation and insertion mechanism.

Specificity and Role of the Borrelia burgdorferi CtpA Protease in Outer Membrane Protein Processing

Anaplasma phagocytophilum Outer Membrane Protein A Interacts with Sialylated Glycoproteins To Promote Infection of Mammalian Host Cells

The decreased protection in IgG1 - deficient mice correlates with less efficient bacterial opsonization and uptake by macrophages, and this reflects the low binding of outer membrane protein OmpD - specific IgG2a to the bacterial surface.

Previously, we have shown that purified S. Typhimurium porins including outer membrane protein OmpD, which induce both IgG1 and IgG2a in mice, provide protection to S. Typhimurium infection via Ab.

Not exact matches

Seeking alternatives to conventional antibiotics, Anna de Breij and colleagues at Leiden University Medical Center in the Netherlands developed SAAP - 148 — a short protein fragment, or peptide, that kills bacteria by poking holes in their outer membranes.

Tom40 forms a channel in the outer mitochondrial membrane that is used to import proteins.

Several studies have used cell - surface markers — proteins found on the outer membranes of tumor cells — to identify glioblastoma stem cells; but the specific markers used have been controversial and can not reflect molecular processes going on within tumor cells.

The virus binds with the host cell's outer membrane via a pocket lined with a protein called clatherin.

Toward the end of her postdoc, Chacinska identified a protein called Mia40, whose role was to transport precursor proteins to the space lying between the outer and inner membranes of mitochondria.

In one, researchers working with mice at the Institute of Molecular and Cellular Biology in Singapore used antibodies to target proteins inside cancer cells — an impressive feat, since the antibodies were long considered too large to cross the cancer cell's outer membrane.

In Gram - negative bacteria, BAM is responsible for the biogenesis of beta - barrel proteins on the cells» outer membranes.

Transport proteins are responsible for moving materials such as nutrients and metabolic products through a cell's outer membrane, which seals and protects all living cells, to the cell's interior.

Interactions of these proteins with the outer membrane in vivo and in vitro are well known, allowing for direct comparisons with the synthetic model.

All human cells contain a protein called CD47 on their outer membrane coat.

Cell biologists previously didn't know whether the LppA protein propped up the cell wall, like pillars prop up a roof, or whether the outer membrane was tethered to the cell wall.

A cell membrane, plasma membrane or plasmalemma is a selectively permeable lipid bilayer coated by proteins which comprises the outer layer of a cell.

Hughes» graduate student Eli Cohen pursued the question of rod length control in Salmonella enterica using genetic tools with slow progress until, in one of his courses, he heard about the concept of the outer membrane tethering protein Lpp, that physically links the outer membrane to the cell wall.

The Listeria protein snippet apparently prompts the macrophage to obliterate the escaped protein once it's out of the vacuole but before it can get to the macrophage's outer membrane, suggests Patrick Berche, a microbiologist at the Necker Hospital in Paris.

Given that, then why doesn't the protein also chew through the cell's outer membrane and kill it?

For this purpose, its outer membrane has protein import channels consisting of molecules with a barrel structure, so - called beta - barrel proteins.

Subsequently, the sorting and assembling machinery (SAM) was identified in the mitochondrial outer membrane, which is required for the insertion of the barrel proteins.

As a part of the innate immune system, Cd14 helps the body respond to bacterial infections by producing a protein that binds to lipopolysaccharides within the outer membranes of some bacteria.

Subjecting N. gonorrhoeae to the phenotypic microarray screening method for the first time, Sikora's team focused on seven proteins from the bacteria's cell envelope, which consists of the outer membrane, the cell wall and the inner membrane.

By interacting with the actin cytoskeleton, underneath the cell outer membrane, and other structural proteins of the tight junctions, Alix ensures the formation of the actomyosin - tight junction complex at a specific position between adjacent cells.

The viruses also induce the bacteria to produce a second set of proteins that helps guide the assembly of P22 spheres, from the coat proteins, on the outer surface of the cell membrane.

The chaperone prevents the subunit from interacting with other proteins and carts it off to an usher protein on the bacterium's outer membrane.

The protein LecA on the surface of the bacteria binds to sugar on special lipid molecules, so - called Gb3 lipids, which are present in the outer membrane of human cells.

Two accessory proteins orchestrate the Cpx - TCS: The periplasmic protein CpxP inhibits the Cpx - TCS in unstressed cells and detects misfolded envelope proteins; the outer membrane lipoprotein NlpE activates the Cpx - TCS during biofilm formation.

The TOMM40 gene encodes a barrel - shaped protein in the outer membrane of mitochondria that forms a channel for molecules — including the precursor to amyloid — to enter.

A New Fluorescent Probe for Protein Interactions More Proof of Outer Membrane Cytochrome Role in Electron Transfer Scientists Show How Bacteria Move Electrons Across a Membrane

«Targeted Protein Degradation of Outer Membrane Decaheme Cytochrome MtrC Metal Reductase in Shewanella oneidensis MR - 1 Measured Using Biarsenical Probe CrAsH - EDT2.»

Results: A recent study of the contaminant - reducing bacterium Shewanella oneidensis provides the first evidence that the microbe maneuvers proteins within the bacterial cell into its outer membrane to contact metal directly.

The surface - exposed outer - membrane protein ErpX was identified as having affinity for laminin, and is the first laminin - binding protein to be identified in a Lyme disease spirochaete.

Single - point single - molecule FRAP distinguishes inner and outer nuclear membrane protein distribution.

Publishing online in Science, the researchers report that the molecule to which progesterone must bind is the enzyme alpha / beta hydrolase domain containing protein 2 (ABHD2), found in the sperm cell's outer membrane.

Solution - NMR characterization of outer - membrane protein A from E. coli in lipid bilayer nanodiscs and detergent micelles.

In 2005, researchers identified a mammalian protein they termed 1,25D3 - MARRS present in the outer membrane of intestinal cells that induces a rapid response to vitamin D, enhancing the transport of phosphorus31 and possibly calcium32 into the cell, showing that not all of vitamin D's actions occur through the VDR.