Sentences with phrase «outer segments of»

Previous studies have shown the requirement of CNGB1 for normal targeting of CNGA1 to the rod outer segment [16] and indeed the authors were able to demonstrate a lack of detectable CNGA1 protein in the rod outer segments of the affected Papillons homozygous for the mutation [15].

The gene product's precise role is not currently understood but it is thought to anchor regulatory complexes at the photoreceptor connecting cilium, which acts as a bridge between the inner and outer segments of photoreceptor cells [43] as well as having functions in disk morphogenesis [42] and in the structure of the ciliary axoneme [44].

Conservation of visual acuity in the iPS - RPE transplanted eyes was associated with the preservation of photoreceptors in the host outer nuclear layer (ONL — Fig. 7A), identified by the expression of rhodopsin in the outer segments of photoreceptors (Fig. 7A inset, Dystrophic + transplant).

Microfluorometric Measurement of the Formation of All - Trans - Retinol in the Outer Segments of Single Isolated Vertebrate Photoreceptors.

Reduction of all - trans retinal to all - trans retinol in the outer segments of frog and mouse rod photoreceptors.

The active cryptochrome 1 is found in the light - sensitive outer segments of the cone cells.

The outer segment of your biceps, or the long - head, is generally much more easily activated by more vertical or pronate grip.

Not exact matches

Once all the slits are cut, pick up the outer edge of each segment while pressing gently on the center edge of the segment.

I RECENTLY entered a local darts tournament where, to make things more difficult, most of the standard board had been covered up, leaving only six of the segments and the outer bull on which to score.

The rod outer segment is made up of stacked discs each containing many types of proteins, in particular rhodopsin, a light - sensitive pigment.

Optical Coherence Tomography (OCT) imaging revealed the loss of outer segments in foveal cone cells in the «optical gap» of a patient with ATF6A defects.

In wild - type, retinal ganglion cell layer (GCL), inner nuclear layer (INL), inner plexiform layer (IPL), and nuclear layers of rod and cone photoreceptors are distinct, and rod outer segment (OS) is observed at the outer-most layer of the retina.

Lack of protein - tyrosine sulfation disrupts photoreceptor outer segment morphogenesis, retinal function and retinal anatomy.

Syntaxin 3 and SNAP - 25 pairing, regulated by omega - 3 docosahexaenoic acid, controls the delivery of rhodopsin for the biogenesis of cilia - derived sensory organelles, the rod outer segments.

Rim formation is not a prerequisite for distribution of cone photoreceptor outer segment proteins.

Rapid formation of all - trans retinol after bleaching in frog and mouse rod photoreceptor outer segments.

Effect of Rds abundance on cone outer segment morphogenesis, photoreceptor gene expression, and outer limiting membrane integrity.

In this well - studied model of autosomal recessive retinitis pigmentosa and secondary photoreceptor degeneration, a MERTK mutation in the RPE compromises their ability to phagocytose shed photoreceptor outer segments [35]--[37].

Mfrprd6 mice demonstrate abnormal RPE microvilli development, a delay in outer segment development, an impaired ability to phagocytize shed OSs, and potentially, an impairment of adhesion between RPE and outer segments.

Fresh porcine retinal tissue was dissected, orientated on a 0.45 mm filter with the photoreceptor cell surface uppermost and placed on top of the iPS - RPE monolayer so that outer segments were adjacent to the RPE.

(B - i) Electron microscopy image of a porcine photoreceptor outer segment (POS) adjacent to an iPS - RPE cell following 3 hours co-culture with a porcine retina explant.

The progression of retinal dystrophy in the RCS rat is such that by 13 weeks post-graft most of the ONL has disappeared [33] and the photoreceptor outer segment layer is reduced to a debris zone [40], a finding we observed in dystrophic controls.

(E) Rhodopsin - positive material (red) is present within the cell membrane of human specific marker (HSM)- labelled iPS - RPE (green) 8 days post-transplantation and in the tips of the host outer segment (OS) layer.

(A) Confocal images showing phagocytosis of isolated FITC - labelled porcine photoreceptor outer segments (POS — green) by iPS - RPE in culture.

Phagocytosis of fluorescently labelled photoreceptor outer segments (green) by iPS - RPE cells in vitro.

Importantly, akin to HESC - RPE in vivo, cells at the outside edge of the iPS - RPE cell bolus could phagocytose photoreceptor outer segments from the RCS rat, as indicated by the presence of rhodopsin - positive photoreceptor material within the cellular membrane of iPS - RPE labelled with HSM (Fig. 5E).

Phagocytosis of photoreceptor outer segments was defined by the inclusion of rhodopsin - labelled material within the TRA -1-85-bordered intracellular compartment of grafted human iPS - RPE cells.

Immunocyctochemistry was also used to assess phagocytosis of host outer segments in vivo.

The director has done long scenes before — a seven - minute segment in «Children of Men» is especially memorable — but he's never pulled one off with all the built - in barriers of working in a facsimile of outer space.

Their outer segments are upholstered in black Nappa leather; anthracite - coloured Nappa leather («Light Anthracite») is used towards the inner surfaces in the area of the lateral seat supports and towards the head section.

The outer ring comprises of the LED light while the inner segment is fitted with laser diodes to produce laser light.

They are subdivided into two segments — the inner sections have honeycomb screen inserts, while their outer sections, made of CFRP, have a smooth funnel shape.

The Earth has a synod conjunction with each of the four major gas planets with a little over a year between impulses, (~ +2 days for Neptune, ~ +4 days for Uranus, ~ +13 days for Saturn, ~ +34 days for Jupiter) these past almost annual periods could be segmented and applied into the composite forecast as an adjustment algorithm to further enhance the pattern match, to increase the accuracy (~ 85 %) of the inner planet 6558 day pattern to closer to 95 % with the addition of the compensation for the outer planet interactive influences.