The tumor - suppressor gene ARHI (DIRAS3) suppresses
ovarian cancer cell migration through inhibition of the Stat3 and FAK / Rho signaling pathways.
To test this idea, they experimentally reduced the expression of the DNM30S lncRNA, which resulted in reduced
ovarian cancer cell migration and invasion.
Not exact matches
EMT is important for
cell migration and invasion — two characteristic of metastatic
cancer cells — strongly suggesting that the link between lncRNAs and EMT contributes to the metastatic progression of
ovarian cancer.
In a study observing its effects on
ovarian cancer cells and
cell - mediated responses, Reishi inhibited
cell colony formation and
cell migration demonstrating its ability to protect already healthy
cells.