Not exact matches
Shih, Wang and their colleagues tested fostamatinib's power to reduce tumor size in mice implanted with human
ovarian cancer cells that were
resistant to paclitaxel.
The researchers then used a combination of existing United States Food and Drug Administration - approved drugs to target autophagy and found
ovarian cancer cells to be highly sensitive to these drugs in several different mouse
cancer models — even among
cells resistant to standard chemotherapy.
The study evaluated 56 patients with
ovarian clear
cell adenocarcinoma (CCA), an aggressive form of
ovarian cancer that is more likely to be
resistant to chemotherapy and to have a poorer prognosis than other forms of this disease.
«A way to kill chemo -
resistant ovarian cancer cells: Cut down its protector.»
In addition to the afatinib -
resistant NSCLC
cells, the researchers tested the neratinib and valproic acid combination on
cell lines derived from human pancreatic and
ovarian cancers containing K - Ras mutations and N - Ras mutations, respectively.
Indomethacin killed both drug -
resistant and drug - sensitive epithelial
ovarian cancer cells.
Interestingly, cisplatin -
resistant epithelial
ovarian cancer cells were most sensitive to indomethacin.
«We think that by isolating the CA125 - negative tumor
cells we have uncovered this reservoir of carboplatin -
resistant high - grade serous
ovarian cancer cells.»
«This study provides evidence that CA125 - negative high - grade serous
ovarian cancer cells have stem properties and are inherently platinum
resistant.
«Surviving
ovarian cancer: Scientists attack drug
resistant cancer cells.»
The use of two drugs never tried in combination before in
ovarian cancer resulted in a 70 percent destruction of
cancer cells already
resistant to commonly used chemotherapy agents, say researchers at Mayo Clinic in Florida.
Major Discovery in
Ovarian Cancer Investigators linked mutations in two genes to ovarian clear cell carcinoma, one of the most aggressive and treatment - resistant forms of ovarian
Ovarian Cancer Investigators linked mutations in two genes to ovarian clear cell carcinoma, one of the most aggressive and treatment - resistant forms of ovarian c
Cancer Investigators linked mutations in two genes to
ovarian clear cell carcinoma, one of the most aggressive and treatment - resistant forms of ovarian
ovarian clear
cell carcinoma, one of the most aggressive and treatment -
resistant forms of
ovarian ovarian cancercancer.