«New test could detect
ovarian cancer patients who are strongly responding to treatment.»
Not exact matches
In a 564 - person trial,
patients whose
ovarian cancer recurred (and
who had already started treatment with chemotherapy) given Rubraca, part of a new class of
cancer drugs called «PARP» inhibitors, lived, on median, for double the amount of time without their disease getting even worse compared with those given a placebo.
For instance, a plaintiff in the Supreme Court case, Ellen T. Matloff of Yale
Cancer Center, said that in 2006 she knew of a patient who had had breast and ovarian cancer who tested negative for BRCA1 and BRCA2, suggesting that this patient's cancers were not the result of a hereditary condition, according to the New York
Cancer Center, said that in 2006 she knew of a
patient who had had breast and
ovarian cancer who tested negative for BRCA1 and BRCA2, suggesting that this patient's cancers were not the result of a hereditary condition, according to the New York
cancer who tested negative for BRCA1 and BRCA2, suggesting that this
patient's
cancers were not the result of a hereditary condition, according to the New York Times.
A study done by researchers at Fox Chase
Cancer Center shows that many relatives of
patients who undergo testing for a gene linked to breast and
ovarian cancers misinterpret the results, and less than half of those
who could benefit from genetic testing say they plan to get tested themselves — despite the fact that knowing your genetic status may help catch the disease in its earliest stages.
The researchers also are seeking other potential drug targets in the 50 percent of
patients who don't have high levels of the anti-death protein, as well as biomarkers in addition to CA125 that could be used to screen for
ovarian cancer.
«Once the
ovarian cancer becomes drug resistant we can not cure it,» says Rodriguez a gynecologic oncologist who provides treatment to ovarian cancer patients and is director of the precision medicine initiative at Rutgers Cancer Institute of New J
cancer becomes drug resistant we can not cure it,» says Rodriguez a gynecologic oncologist
who provides treatment to
ovarian cancer patients and is director of the precision medicine initiative at Rutgers Cancer Institute of New J
cancer patients and is director of the precision medicine initiative at Rutgers
Cancer Institute of New J
Cancer Institute of New Jersey.
The ENGOT - OV16 / NOVA trial evaluated the efficacy and safety of the PARP inhibitor niraparib as maintenance therapy in
patients with recurrent
ovarian cancer who respond to platinum - based chemotherapy.
Longer term, they want to quickly diagnose additional
cancer types, including
ovarian and pancreatic
cancers, which are fast - spreading and require early detection for a
patient to survive, says Goda,
who was recently appointed as a chemistry professor at the University of Tokyo but will continue his research with U.C.L.A..
It has had particularly strong results in phase III trials in
patients who inherited mutations to the BRCA genes, many of whom had breast or
ovarian cancer.
He concluded: «Once it is approved by the regulatory authorities, I'll consider niraparib for all my
patients with recurrent
ovarian cancer who respond to platinum regardless of BRCA status.»
Cancer patients who have
ovarian tissue removed and stored for later transplantation have a chance at a successful pregnancy, a new study finds.
Patients with stage 2, 3, and 4
ovarian cancer who are in complete remission after first - line treatment;
The poor survival in advanced
ovarian cancer is due both to late diagnosis, as well as to the lack of effective second - line therapy for
patients who relapse.
In that randomized, double - blind, placebo - controlled, phase III trial, 561
patients with recurrent epithelial
ovarian, fallopian tube, or primary peritoneal
cancer who were in complete or partial response to platinum - based chemotherapy were treated with either rucaparib 600 mg orally twice daily (372
patients) or to placebo (189
patients).
Platinum - sensitive
ovarian cancer patients with a positive predictive AGO score
who undergo a secondary debulking surgery after relapse on platinum chemotherapy experience longer progression - free survival.
Doctors often fail to recommend genetic testing for breast -
cancer patients, even those
who are at high risk for mutations linked to
ovarian and other
cancers, according to a study published Tuesday.
Coukos,
who is currently leading an
ovarian cancer clinical trial sponsored by CRI's Clinical Accelerator, sought to understand why PD - 1 / PD - L1 immunotherapies are often ineffective for these
patients, even though
ovarian tumors are often infiltrated by «killer» T cells that recognize tumor - specific neoantigens and express high levels of PD - 1.
ZEJULA is the first and only once - daily PARP inhibitor for the maintenance treatment of adult
patients with recurrent epithelial
ovarian, fallopian tube, or primary peritoneal
cancer who are in a complete or partial response to platinum - based chemotherapy.1 - 3
ZEJULA is indicated for the maintenance treatment of adult
patients with recurrent epithelial
ovarian, fallopian tube, or primary peritoneal
cancer who are in a complete or partial response to platinum - based chemotherapy.
Overholser and colleagues discuss the role of endocrine therapy to reduce risk for breast
cancer, and cite interesting data from
patients who developed premature
ovarian failure due to
ovarian irradiation or alkylating chemotherapeutic agents, which demonstrates that these
patients were at decreased risk for developing subsequent breast
cancer.
Research shows that hospitals that treat more than 20
ovarian cancer cases a year and surgeons
who operate on more than 10 cases a year have significantly better
patient outcomes than lower volume hospitals and surgeons, according to the Valley Health System.
We also work with oncologists and other doctors
who understand the severity and life - risks for
ovarian cancer patients.