Currently, she is investigating how inhibiting aldehyde dehydrogenase can kill
ovarian cancer stem cells by inducing necroptosis.
Researchers led by Patricia Donahoe and Xiaolong Wei of Massachusetts General Hospital and Harvard Medical School found that the common chemotherapy agent doxorubicin actually encourages the growth of
ovarian cancer stem cells.
Not exact matches
Without this regulation, lack of Sxl expression in
stem cells can result in the development of
ovarian cancer.
«In pancreatic,
ovarian and liver
cancers, we hope that by adding anti-cancer
stem cell drugs to standard of care, we can control proliferating cells within the tumor that could otherwise help the tumor regenerate in the face of existing chemotherapies.»
«This study provides evidence that CA125 - negative high - grade serous
ovarian cancer cells have
stem properties and are inherently platinum resistant.
«We expect that the proposed treatment will be especially effective in advanced stages of
ovarian cancers, where there are many
cancer stem cells in the tumors that resist conventional drug treatment,» says Minko.
In the proposed project, Dr. Lampi Hermanson will produce NK cells from
stem cells, inserting a chimeric antigen receptor (CAR) with the capacity to recognize mesothelin cells, which is expressed in 70 % of
ovarian cancer patients.
$ 1.8 M Supports
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Cancer Ribbon?
The Xie Lab demonstrated that differentiation - defective Drosophila
ovarian germline
stem cells (GSCs), behaving like human
cancer stem cells, can out - compete normal
stem cells for a position in the niche.
Her research interests are focused on two main areas (1) the contribution of
stem cells to breast and
ovarian cancer progression.
Review of «Induced Pluripotent
Stem Cell - Derived Natural Killer Cells for Treatment of
Ovarian Cancer» from
Stem Cells by Stuart P. Atkinson
Induced Pluripotent
Stem Cell - Derived Natural Killer Cells for Treatment of
Ovarian Cancer.
He is the principal investigator of an NCI - funded, multi-million-dollar Specialized Program of Research Excellence (SPORE) in
ovarian cancer, and he is the principal investigator of a multi-million-dollar grant from the New York State
Stem Cell Science program (NYSTEM) to pioneer a novel strategy of reprogramming human mature T cells and hematopoietic stem cells for generating sustained attack against ovarian cancer in patie
Stem Cell Science program (NYSTEM) to pioneer a novel strategy of reprogramming human mature T cells and hematopoietic
stem cells for generating sustained attack against ovarian cancer in patie
stem cells for generating sustained attack against
ovarian cancer in patients.
Of great interest,
stem - like cells have also been discovered in some cultured
cancer cell lines, including glioma (22, 23),
ovarian (24, 25), liver (26), and prostate (27 — 29)
cancer cells.
I believe that weight gain and most NCDs (non-communicable diseases): high cholesterol, high blood pressure, type 2 diabetes, metabolic syndrome, insulin resistance, polycystic
ovarian syndrome, low testosterone, renal issues and even some
cancers stem from pancreatic abuse.