"Ovarian carcinoma" refers to a type of cancer that starts in the cells of a woman's ovaries, which are the reproductive organs that produce eggs.
Full definition
ab51608 staining HIF -1-alpha in
Human ovarian carcinoma tissue sections by Immunohistochemistry (IHC - P - paraformaldehyde - fixed, paraffin - embedded sections).
Hodi FS, Mihm MC, Soiffer RJ, Haluska FG, Butler M, Seiden MV, Davis T, Henry - Spires R, MacRae S, Willman A, Padera R, Jaklitsch MT, Shankar S, Chen TC, Korman A, Allison JP, Dranoff G. Biologic activity of cytotoxic T lymphocyte - associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and
ovarian carcinoma patients.
Nearly a third of all cancer drugs target G protein - coupled receptors, of which fractalkine is one, so «we reasoned that blocking it may prevent or reduce ovarian cancer metastasis, because it's expressed in 64 percent of
metastatic ovarian carcinoma specimens,» Barbolina said.
One of the most relevant findings of this study is that the observed epigenetic features of these cells are also present in myeloid - derived suppressor cells isolated from patients
with ovarian carcinoma.
Previous TCGA research showed that a form of ovarian cancer (high - grade
serous ovarian carcinoma) and a subtype of breast cancer (basal - like breast cancer) share many genomic features.
Preti is using his work, for instance, to develop ways of sniffing out certain cancers, like melanomas and
ovarian carcinoma, which release volatile, detectable biomarkers.
«In addition to mutations in cancer genes previously identified in uterine and
ovarian carcinomas, we found an excess of mutations in genes encoding specific groups of proteins, which may potentially explain their mixed tissue characteristics,» said Santin.
The Cancer Genome Atlas research network published a landmark study of high - grade serous
ovarian carcinoma, the first of several common cancers to be characterized by TCGA.
We demonstrated that the other MAP3K, MAP3K8, accumulates in high - grade
ovarian carcinomas and is a new prognostic marker for these tumours.
Recent work from our group and others has implicated the fallopian tube (FT) secretory cell as the likely cell - of - origin for a majority of high - grade serous
ovarian carcinomas.
Roman Spektor (Soloway Lab) Effects of lead toxicity on methylation and transcriptional landscapes in the mouse central nervous system Robert Yamulla (Schimenti Lab) Drivers of High Grade Serous Ovarian Carcinoma