Sentences with phrase «ovarian cells from»

Normally, these genes stop breast and ovarian cells from growing and dividing uncontrollably.

The team tried this method with two types of body cells: ovarian cells from an adult and connective tissue cells from a fetus.

Rodriguez wondered if the same association might exist in humans, so she analyzed ovarian cells from women undergoing in vitro fertilization at Johns Hopkins» infertility clinic.

Not exact matches

Because the Augment technique uses mitochondria from the mother's ovarian stem cells rather than a donor, there is no three - parent ethical quagmire to wade through.

Zain Rajani's mother had her eggs «rejuvenated» using mitochondria from her ovarian stem cells.

In the paper, published in the now - defunct online journal e-biomed, West, Lanza and their colleagues showed that they could pull a nucleus from a human egg cell, replace it with a whole adult ovarian cell and generate an embryo that divided into six cells.

The study published in Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy cells.

Beyond lung cancer, TiY is able to target TICs in 28 types of human cell lines derived from the central nervous system, melanoma, breast, renal, ovarian, colon, and prostate cancer.

The key discovery made by the CSHL team is that FER is able to activate a receptor on the surface of ovarian cells «from below,» as it were — by interacting with a portion of the receptor that penetrates the cell membrane and plunges into the cytoplasm.

Analyzing white blood cells from 934 patients and 1,698 healthy controls, they found BRCA1 methylation among 6.4 % of patients diagnosed with ovarian cancer, contrasting 4.2 % among controls.

In addition to the afatinib - resistant NSCLC cells, the researchers tested the neratinib and valproic acid combination on cell lines derived from human pancreatic and ovarian cancers containing K - Ras mutations and N - Ras mutations, respectively.

The researchers then exposed cells from each of these lines to a panel of 31 different drug treatments — including 23 chemotherapy compounds approved by the FDA for breast and ovarian cancers, six targeted cancer drugs, and two common drug combinations.

The research team with international collaborators analysed more than 100 patient samples from ovarian and other cancer types to discover a distinct population of cells found in some tumours.

A section of a tumor organoid grown from cells derived from a patient with high - grade serous ovarian cancer (left) and a mini-tumor treated with ReACp53, resulting in extensive cancer cell death.

Dr. Vasmatzis» research on the «Quantification of Somatic Chromosomal Rearrangements in Circulating Cell - free DNA From Ovarian Cancers» is published in the July 20 edition of Scientific Reports.

Egg cells can also be preserved in their hundreds of thousands by collecting ovarian tissue from reproductively active females that die in captivity and dunking it in liquid nitrogen.

In lab experiments, the research team used cell lines derived from 40 patient tumour samples to identify that CD151 contributes to the survival of cells of high - grade serous ovarian cancer origin.

When the researchers tested the circuit in vitro, they found that it was able to detect ovarian cancer cells from amongst other noncancerous ovarian cells and other cell types.

Analysing certain genes in these cells enabled them to detect 33 per cent of ovarian cancers and 81 per cent of endometrial cancers in Pap test specimens collected from 627 women already diagnosed with these diseases.

In their initial experiments, Hwang and his colleagues used cells from a single donor to try to create embryonic clones; they transferred nuclei from ovarian cells back into the donors» own oocytes.

Ongoing Phase 1b / 2 clinical trials combine entinostat with KEYTRUDA ® from Merck & Co., Inc. for non-small cell lung cancer, melanoma and colorectal cancer; with TECENTRIQ ® from Genentech, Inc. for triple negative breast cancer; and with BAVENCIO ® from Pfizer Inc. and Merck KGaA, Darmstadt, Germany, for ovarian cancer.

The study team assessed three sets of outcomes: a maturational index (MI) based on epithelial cells from the children's urogenital tissue; ultrasound measurements of uterine, ovarian and testicular volume, as well as breast - buds; and hormone concentrations seen in blood tests.

In the proposed project, Dr. Lampi Hermanson will produce NK cells from stem cells, inserting a chimeric antigen receptor (CAR) with the capacity to recognize mesothelin cells, which is expressed in 70 % of ovarian cancer patients.

The earliest and one of the most striking came from observations that the presence of infiltrating T cells (called «tumor - infiltrating lymphocytes,» or TILs) in ovarian tumors is positively and strongly associated with improved survival of patients with ovarian cancer [1].

Their theory was first confirmed with ovarian cancer cell lines and then the Peter / Lengyel team tested HGMA2 protein levels in tumor samples from 100 patients with ovarian cancer.

The book introduces the incessant menstruation hypothesis, which may allow physicians to better understand and explain to patients why many serous ovarian cancers may actually be originating from the fimbriated end of the fallopian tube and why endometrioid and clear cell cancers may arise in association with endometriosis.

Surveillance of the tumor mutanome by T cells during progression from primary to recurrent ovarian cancer.

Her expertise includes isolation of stem cells from multiple organs as well as from solid tumours and fluid aspirates associated with breast and ovarian tumours.

December 17, 2013 Cancer genetics pioneer Janet Rowley, 1925 - 2013 A pioneer in connecting the development of cancer with genetic abnormalities, Janet D. Rowley, MD, the Blum - Riese Distinguished Service Professor of Medicine, Molecular Genetics & Cell Biology and Human Genetics at the University of Chicago, died from complications of ovarian cancer on December, 17, 2013, at her home.

Six ovarian factors (BDNF, IGF - I, estradiol, GDNF, leptin and FGF2) were further studied based upon the expression of their receptors in oocytes and cumulus cells described above, as well as the availability of growth factor concentration information from previous animal model studies [1], [20], [21], [22], [23].

Review of «Induced Pluripotent Stem Cell - Derived Natural Killer Cells for Treatment of Ovarian Cancer» from Stem Cells by Stuart P. Atkinson

He is the principal investigator of an NCI - funded, multi-million-dollar Specialized Program of Research Excellence (SPORE) in ovarian cancer, and he is the principal investigator of a multi-million-dollar grant from the New York State Stem Cell Science program (NYSTEM) to pioneer a novel strategy of reprogramming human mature T cells and hematopoietic stem cells for generating sustained attack against ovarian cancer in patients.

Mock - infected control (A); Severe hemorrhage and regression of ovarian follicles (B); Spleens from mock - infected control (left) and enlarged spleens from the infected ducks (C); HE - stained ovary section showing hemorrhage and follicle rupture with red stained bodies (D); HE - stained brain section revealing lymphocytes and mononuclear cell infiltration under cranial arachnoid (E) and focal gliosis (arrow)(F).

Olaparib is a PARP inhibitor, which is already used to treat certain ovarian cancer patients and prevents damaged cancer cells from repairing themselves after chemotherapy or radiotherapy.

To prepare ovarian cells, ovarian tissues were isolated from 1 - day - old F2 female mice produced by interbreeding C57BL6 × CBA F1 mice.

Their three - dimensional cell - culture system, adapted for high - throughput screening, has enabled them to identify small molecules that can inhibit adhesion and invasion, preventing ovarian cancers from spreading to nearby tissues.

October 30, 2011 Fat cells in abdomen fuel spread of ovarian cancer A large pad of fat cells that extends from the stomach and covers the intestines provides nutrients that promote the spread and growth of ovarian cancer, reports a research team based at the University of Chicago in the journal Nature Medicine, published online October 30th, 2011.

A large pad of fat cells that extends from the stomach and covers the intestines provides nutrients that promote the spread and growth of ovarian cancer, reports a research team based at the University of Chicago in the journal Nature Medicine, published online October 30th, 2011.

The approach developed by the MGH team starts with the engineered protein, which in this case fuses an antibody fragment targeting a protein called mesothelin — expressed on the surface of such tumors as mesothelioma, ovarian cancer and pancreatic cancer — to a protein from the tuberculosis bacteria that stimulates the activity of dendritic and other immune cells.

Using state - of - the - art proteomics and associated computational methods, the Speicher laboratory is investigating protein changes associated with ovarian cancer, melanoma, cardiac injury resulting from breast cancer therapies, ectopic pregnancy, red cell diseases, and other clinical disorders.

February 10, 2015 New screening tool could speed development of ovarian cancer drugs University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis.

University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis.

Next, ovarian cancer cells, expressing a fluorescent marker to distinguish them from the other cells, were added.

According to the American Cancer Society, ginger can combat ovarian cancer by blocking the cancer cells from growing, preventing it from spreading and causing more harm to the body.

For the study, Levine and his colleagues performed genetic analyses of ovarian cancer cells from 96 patients.