Research appearing in Developmental Cell details the discovery of genes located in two genomic regions whose copy numbers are increased in response to differentiation of
the ovarian follicle cells.
Not exact matches
During an IVF cycle, a woman receives fertility drugs that stimulate
ovarian cells in the
follicle.
As a result, the
follicle, which contains the
ovarian cells and the egg, gets bigger, estrogen levels rise, and the egg matures.
That
ovarian tissue bears clusters of
cells known as primordial
follicles, which surround immature precursors to egg
cells.
The researchers isolated primary
ovarian follicles, consisting of the oocyte and surrounding
cells.
That geometry directly links to whether or not the
ovarian follicles, organized hormone - producing support
cells surrounding an immature egg
cell, will survive in the ovary, which was one of the bigger findings in the study.
The Colorado lab discovered that granulosa
cells — the
cells that surround maturing eggs in the
ovarian follicles — were pumping out leptin and shipping it into the egg.
Nonetheless, it has become increasingly clear that the fate of an embryo may be cast in the
ovarian follicles, where egg
cells are built.
In biology, folliculogenesis refers to the maturation of the
ovarian follicle, a densely - packed shell of somatic
cells that contains an immature oocyte.
Mock - infected control (A); Severe hemorrhage and regression of
ovarian follicles (B); Spleens from mock - infected control (left) and enlarged spleens from the infected ducks (C); HE - stained ovary section showing hemorrhage and
follicle rupture with red stained bodies (D); HE - stained brain section revealing lymphocytes and mononuclear
cell infiltration under cranial arachnoid (E) and focal gliosis (arrow)(F).
Recent studies have demonstrated that mouse ES
cells can differentiate into female and male germ
cells in vitro, thus producing
ovarian follicle - like structures [1], [4] and testicular germ
cells 2, 3.
Programs with research emphasis on signal transduction in development and oncogenesis,
cell adhesion molecules in development and oncogenesis, muscologskeletal atrophy and countermeasures,
ovarian follicle development, neural regeneration, implantable therapeutic or diagnostic devices and application of computers in veterinary education.