One would think that if there is a remnant of
ovarian tissue in the spayed pet's abdomen, the surgeon must have left it behind.
Not exact matches
Sara Matthews, a consultant gynecologist at the Portland hospital, said that within three months of having her
ovarian tissue re-implanted, Al Matrooshi went from being menopausal to having the ovary function of a normal woman
in her 20s.
In July, a 33 - year - old woman in Edinburgh became the first in Britain to give birth after having frozen ovarian tissue returned to her bod
In July, a 33 - year - old woman
in Edinburgh became the first in Britain to give birth after having frozen ovarian tissue returned to her bod
in Edinburgh became the first
in Britain to give birth after having frozen ovarian tissue returned to her bod
in Britain to give birth after having frozen
ovarian tissue returned to her body.
Helen Picton, who oversaw the
tissue - freezing at Leeds University, told the BBC that
in Europe alone, several thousand girls and young women have had
ovarian tissue frozen and stored.
As humans, we've developed ways to donate blood,
tissue, organs, and even sperm and
ovarian eggs
in recent generations, but human milk has been shared since women began having babies.
For it to be useful, cryopreserved
ovarian tissue must thaw
in a way that maintains its original cellular structure and function.
Zelinski and her colleagues have found they can reliably thaw
ovarian tissue by placing it
in a series of solutions with lower concentrations of sucrose, a medical - grade table sugar.
ONPRC researchers also have been investigating two ways of maturing follicles from cryopreserved, thawed
tissue: transplanting strips of
ovarian tissue back into a monkey's body, or growing the
tissue in vitro by encapsulating individual follicles
in a biomaterial that mimics an ovary.
In this study, researchers analyzed ovarian tissue from populations of reproductively «young» (equivalent to women in their early twenties) and «old» mice (equivalent to women ages 38 - 45
In this study, researchers analyzed
ovarian tissue from populations of reproductively «young» (equivalent to women
in their early twenties) and «old» mice (equivalent to women ages 38 - 45
in their early twenties) and «old» mice (equivalent to women ages 38 - 45).
If the approach works
in women it could be used to boost fertility or help those who froze
ovarian tissue prior to chemotherapy.
309
ovarian tissue freezing procedures resulted
in 84 births and 8 pregnancies that lasted beyond the first trimester.
This resulted
in the conception of a boy with normal genitalia and a girl who was developing both
ovarian and testicular
tissue.
So his team looked for cells with vasa still on their surface
in human
ovarian tissue.
The HFEA report had the same reason for opposing the use of fetuses, albeit
in less emotive language: «The public... may feel an instinctive repugnance to the use of
ovarian tissue from these sources for research or fertility treatment.»
Spontaneous immune responses were assessed by measuring serum antibodies against
ovarian cancer - associated antigens, such as NY - ESO - 1, that are not expressed
in normal body
tissues but are expressed
in cancers.
These claims were based on subjective observations of
ovarian tissue and on the behavior of extremely rare
ovarian cells following extensive growth
in tissue culture, a procedure that is capable of «reprogramming» cells.
Researchers from Haukeland University Hospital
in Bergen, Norway, and colleagues analyzed for potential impact of normal
tissue BRCA1 methylation on
ovarian cancer risk.
A HUMAN ovary grown
in the lab from slivers of
ovarian tissue has been able to turn an immature egg into one that is ready to be fertilised.
In a world first, Ouarda Touirat, a 32 - year - old cancer survivor in Belgium, delivered a healthy baby this year after undergoing an ovarian tissue transplan
In a world first, Ouarda Touirat, a 32 - year - old cancer survivor
in Belgium, delivered a healthy baby this year after undergoing an ovarian tissue transplan
in Belgium, delivered a healthy baby this year after undergoing an
ovarian tissue transplant.
Tal Biron - Shental, a gynecologist at Meir Hospital
in Israel, also faced intense criticism when she described her team's attempts to cultivate
ovarian tissue from 22 - to 33 - week - old aborted fetuses.
The use of fetal
ovarian tissue for fertility purposes has been banned
in the United Kingdom since 1994.
Recently Kutluk Oktay, the chief of reproductive endocrinology and infertility at New York Methodist Hospital
in Brooklyn, has been experimenting with freezing and transplanting swatches of
ovarian tissue.
While individual, already - developed eggs die easily when frozen, immature follicle eggs embedded
in the
ovarian tissue fare a lot better.
Egg cells can also be preserved
in their hundreds of thousands by collecting
ovarian tissue from reproductively active females that die
in captivity and dunking it
in liquid nitrogen.
«
Ovarian cancer treatments have not changed much
in many decades, and this may be,
in part, because we have been studying the wrong
tissue of origin for these cancers,» says study leader Victor Velculescu, M.D., Ph.D., a professor of oncology at the Johns Hopkins Kimmel Cancer Center.
The need for better access to fertility preservation has become more pressing
in recent years for two reasons: first, the improved rates of survival
in young women and girls diagnosed with cancer; and second, improvements
in the techniques of freezing eggs and
ovarian tissue to restore fertility.
In their research, scientists at Rutgers created animal models that closely resemble the cancerous tumors found in women with ovarian cancer by injecting tumor tissues obtained from gynecological cancer patients treated at the Cancer Institute into laboratory mic
In their research, scientists at Rutgers created animal models that closely resemble the cancerous tumors found
in women with ovarian cancer by injecting tumor tissues obtained from gynecological cancer patients treated at the Cancer Institute into laboratory mic
in women with
ovarian cancer by injecting tumor
tissues obtained from gynecological cancer patients treated at the Cancer Institute into laboratory mice.
For the new study, described
in the October 23rd issue of Nature Communications, scientists at the Johns Hopkins Kimmel Cancer Center and Dana Farber Cancer Institute
in Boston collected
tissue samples containing normal cells,
ovarian cancers, metastases that had spread elsewhere, and small cancers found
in the fallopian tubes, which included single cell layers of cancer called «p53 signatures» and serous tubal intraepithelial carcinoma, or STIC lesions.
Sometimes
ovarian teratomas with brain cells
in can lead to personality changes, paranoid thoughts or seizures if the immune system recognises the
tissue as foreign and starts to attack both it and cells
in the brain.
The study team assessed three sets of outcomes: a maturational index (MI) based on epithelial cells from the children's urogenital
tissue; ultrasound measurements of uterine,
ovarian and testicular volume, as well as breast - buds; and hormone concentrations seen
in blood tests.
The process from beginning to end, starting with immature eggs within
ovarian tissue before reaching mature eggs
in the final bottom right image (Credit: Prof Evelyn Telfer and Dr Marie McLaughlin, the University of Edinburgh)
The process from beginning to end, starting with immature eggs within
ovarian tissue before reaching mature eggs
in the final bottom right image
Most
ovarian cancers are serous carcinomas, which develop
in the
tissue lining the ovaries and are subtyped into high - grade and low - grade.
«This fatty
tissue, which is extraordinarily rich
in energy - dense lipids, acts as a launching pad and energy source for the likely lethal spread of
ovarian cancer,» said study author Ernst Lengyel, MD, PhD, professor of obstetrics and gynecology at the University of Chicago.
A group
in Edinburgh where this work has been pioneered
in the UK has
ovarian tissue stored for many women, but as yet none have returned to have it reimplanted.
«Therefore,» the authors wrote, «FABP4 emerges as an excellent target
in the treatment of intra-abdominally disseminating tumors, which preferentially metastasize to adipose
tissue such as
ovarian, gastric, and colon cancers.»
Clinical and laboratory studies have shown that NY - ESO - 1 is present
in many different cancers — including melanoma, lung, breast, and
ovarian cancers — and not
in most healthy
tissue.
ab51608 staining HIF -1-alpha
in Human
ovarian carcinoma
tissue sections by Immunohistochemistry (IHC - P - paraformaldehyde - fixed, paraffin - embedded sections).
Ovarian tissue is more sensitive to aging than any other
tissue in the human body (whaaat!)
Estrogen (from estrus, meaning «heat» or «fertility») is the dominant hormone for the first week or so after menstruation, stimulating the buildup of
tissue and blood
in the uterus as the
ovarian follicles simultaneously begin their development of the egg.
This is significant because your
ovarian tissue is literally THE most sensitive to aging than any other
tissue in the human body (whaaat!)
Authors conclude «restoration of normal menses was caused by reduced inflammation
in the
ovarian tissue and supports the hypothesis that the gut immune system can influence autoimmune disease and inflammation.»
... The estrogenic compounds of the root are not the type that have an effect on the uterus or the breast
tissue, but rather they are perceived by the hypothalamus of the brain as an estrogen metabolite and tend to lessen the pituitary surges of luteinizing hormone (LH)
in the absence of
ovarian estrogens.
According to the study authors,
tissue and fluid collected during a Pap test can detect endometrial and
ovarian cancer
in women when subjected to genetic testing.
In the situation of this type of tumor, signs of heat are constant; they do not cycle as with
ovarian tissue.
Most likely some
ovarian tissue was left
in the body during surgery and that
tissue releases hormones that cause the animal to go into heat.
Ultrasonography may also be helpful: it shows possible consolidation
in tissues (
ovarian tumor or cyst
in this case).
While the canine ability to detect the presence of
ovarian cancer is well - established, researchers aren't sure exactly which chemicals the dogs are detecting
in the
tissue and plasma samples.
Her team's work builds on that of Swedish researcher György Horvath, who's shown that dogs have a 100 percent sensitivity and 98 percent specificity to detect
ovarian cancer
in plasma and
tissue samples.