Sentences with phrase «ovarian tumor called»
They all had a type of ovarian tumor called a teratoma.
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Razqallah Hakem, a cancer biologist at the University of Toronto in Ontario, and his colleagues normally study a tumor suppressor called BRCA1, variants of which put women at high risk of breast and ovarian cancer.
Importantly, elevated BRCA1 methylation was confined to patients diagnosed with so - called high - grade serous tumors, the most aggressive variant of ovarian cancer, which also is the variant associated with BRCA1 mutations.
In a major breakthrough for ovarian and uterine cancers, Yale researchers have defined the genetic landscape of rare, highly aggressive tumors called carcinosarcomas (CSs), pointing the way to possible new treatments.
Surgeons gathered to focus on a quality improvement program to address a central issue in treating advanced ovarian cancer — how to optimize surgery to achieve complete removal of all visible tumor — also called optimal resection.
The earliest and one of the most striking came from observations that the presence of infiltrating T cells (called «tumor - infiltrating lymphocytes,» or TILs) in ovarian tumors is positively and strongly associated with improved survival of patients with ovarian cancer [1].
Hargreaves brings her knowledge of biochemistry and epigenetic regulation to investigate a subunit of the SWI / SNF complex called ARID1A, which is mutated in many solid tumors, such as in ovarian, bladder and colorectal cancers.
The approach developed by the MGH team starts with the engineered protein, which in this case fuses an antibody fragment targeting a protein called mesothelin — expressed on the surface of such tumors as mesothelioma, ovarian cancer and pancreatic cancer — to a protein from the tuberculosis bacteria that stimulates the activity of dendritic and other immune cells.
A class of drugs called EZH2 inhibitors are currently in clinical development for both hematological malignancies and solid tumors and may be effectively targeted to epithelial ovarian cancers overexpressing the CARM1 protein.