Sentences with phrase «ovarian tumors as»

And although most tumors in horses occur as they get older, this is not the case with ovarian tumors as these commonly occur in horses 5 to 9 years of age.

He previously revealed the existence of spontaneous immune responses in ovarian tumors as well as described how regulatory T cells and tumor blood vessels affect these responses.

Not exact matches

«Nonetheless, the proof of concept studies we have obtained thus far are extremely encouraging, and we are confident that with proper support and efforts we could translate our findings into experimental therapeutics for a variety of solid tumors that are driven by EphA2 overexpression, including breast, lung, prostate, pancreatic, and ovarian cancers,» said Pellecchia, who serves as the founding director of the Center for Molecular and Translational Medicine at UCR.

Wong and his lab want to see if edelfosine could be incorporated into future clinical research focused on other tumor sites such as lung, ovarian and pancreatic cancers.

«This finding,» Villanueva said «opens the door to developing new biomarkers and new therapeutic strategies exploiting these characteristics of exosomes in breast tumors, and other tumors such as ovarian and endometrial cancer among others.»

The study published in Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy cells.

Heeke says the study would be open to people whose tumors have evidence of HRD like those found in this study, which includes bladder, breast, cervix, liver and bile duct, colorectal, endometrial, gastric / esophageal, head & neck, kidney, neuroendocrine, lung, ovarian, pancreas, prostate, sarcoma, and thyroid cancers, as well as gastrointestinal stromal tumors, glioma, melanoma and unknown primary cancers.

BRCA1 and 2, genes whose proteins are supposed to work as tumor suppressors and also repair DNA damage, were the first known risk factor genes for familial breast cancer as well as ovarian and other cancers.

P: We found discodermolide [a drug from Discodermia, a sponge found in the Caribbean, the Bahamas, and the Gulf of Mexico], and it's gone through phase I clinical trials for treatment of solid tumors such as ovarian, pancreatic, breast, colon, or lung cancers.

As proof - of - principle of the potential efficacy, Zhang's team grew human ovarian tumors in immunocompromised mice, then injected short - interfering RNAs to block the tumors» growth using RNA interference against FAL1.

In some cases such as ovarian cancer, however, drug - free intervals are needed to allow patient recovery from side effects, during which tumors can sometimes begin to grow again or develop resistance to the drugs being used.

Although CSs comprise only 2 % -5 % of all uterine malignancies and 1 % -2 % of all ovarian tumors, they are responsible for a disproportionate number of deaths due to their high biologic aggressiveness and resistance to standard treatments, such as radiation and chemotherapy.

The authors studied a standard panel of 60 established human tumor cell lines representing nine different human cancers, as well as several specimens of human primary ovarian cancer.

Hargreaves brings her knowledge of biochemistry and epigenetic regulation to investigate a subunit of the SWI / SNF complex called ARID1A, which is mutated in many solid tumors, such as in ovarian, bladder and colorectal cancers.

The approach developed by the MGH team starts with the engineered protein, which in this case fuses an antibody fragment targeting a protein called mesothelin — expressed on the surface of such tumors as mesothelioma, ovarian cancer and pancreatic cancer — to a protein from the tuberculosis bacteria that stimulates the activity of dendritic and other immune cells.

«Visualizing how cancer cells interact with a tumor microenvironment that accurately reflects the complex biology of ovarian cancer should help us understand the mechanisms underlying metastatic progression as well as identify new therapeutics that can inhibit this process,» said clinical gynecologic oncologist Ernst Lengyel, MD, PhD, senior author of the study and a professor of obstetrics and gynecology at the University of Chicago.

«Therefore,» the authors wrote, «FABP4 emerges as an excellent target in the treatment of intra-abdominally disseminating tumors, which preferentially metastasize to adipose tissue such as ovarian, gastric, and colon cancers.»

The chronically stressed mice had decreased immune function and experienced tumor development significantly earlier than the non-stressed mice.16 Other mouse studies of ovarian cancer showed that chronic stress resulted in increased cancer growth as well as increased angiogenesis, the process with which cancer forms new blood vessels to feed itself nutrients for growth and metastases.17 Chronic stress has also been shown to decrease our body's ability to mount an attack against foreign invaders, including viruses.18 As we know that several viruses can cause cancer (HPV and cervical cancer, and EBV and nasopharyngeal cancer), we can extrapolate that any decrease in immune function could increase cancer risas well as increased angiogenesis, the process with which cancer forms new blood vessels to feed itself nutrients for growth and metastases.17 Chronic stress has also been shown to decrease our body's ability to mount an attack against foreign invaders, including viruses.18 As we know that several viruses can cause cancer (HPV and cervical cancer, and EBV and nasopharyngeal cancer), we can extrapolate that any decrease in immune function could increase cancer risas increased angiogenesis, the process with which cancer forms new blood vessels to feed itself nutrients for growth and metastases.17 Chronic stress has also been shown to decrease our body's ability to mount an attack against foreign invaders, including viruses.18 As we know that several viruses can cause cancer (HPV and cervical cancer, and EBV and nasopharyngeal cancer), we can extrapolate that any decrease in immune function could increase cancer risAs we know that several viruses can cause cancer (HPV and cervical cancer, and EBV and nasopharyngeal cancer), we can extrapolate that any decrease in immune function could increase cancer risk.

Given the well - established role of steroid hormones in breast cancer etiology for postmenopausal women, these findings may have important health implications» Tumor growth from these hormone imbalances is also evident «A dramatic increase in estrogen - dependent malignant diseases, such as ovarian, corpus uteri, breast, testicular and prostate cancers has been recognized.

Although this tumor was thankfully benign, it's important to familiarize yourself with the symptoms of ovarian cancer — especially since most signs of the illness aren't as obvious as a large, fast - growing mass.

Spayed and neutered dogs have an increased incidence of mammary, testicular and ovarian tumors, as you might imagine, since these tumors are affected by the hormones.

In the situation of this type of tumor, signs of heat are constant; they do not cycle as with ovarian tissue.

Reproductive disorders such as pyometra, mammary tumors, testicular cancer, ovarian cancer, and prostate cancer are also reduced / prevented with neutering (reviewed in [2]-RRB- although neutering has been associated with increased risk or aggressiveness of prostatic cancer [3 — 5].

Estrogen is the hormone released during the estrus cycle has been reported as an important factor in the development of various ovarian, uterinal and cervical cat tumors, which can be prevented by spaying cats when young; preferably before the first heat cycle.

Along with birth control, behavioral correction, and removal of sexual frustration, various kinds of reproductive tract problems such as ovarian and uterine tumors, mammary gland tumors and cervical tumors can be prevented with feline spaying.

Spaying is generally thought to reduce a doe's (female rabbit's) risk of uterine and ovarian cancer, as well as occurrences of mammary tumors.

The room must also be dark at night, as exposure to light 24 hours a day is injurious to the health of rodents (it can stimulate the growth of tumors and ovarian cysts).