The budget seeks an additional $ 1.5 billion
over current levels for Head Start, the early childhood education program run by the Department of Health and Human Services.
Not exact matches
Importantly, Series E investors negotiated
for a guaranteed 20 % return upon an IPO, and so their stake is worth $ 180 million at the time of the IPO (and
over $ 250 million at
current trading
levels).
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues
for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement
for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding
for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the
levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications
for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all,
for new and
current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products
over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
At longer horizons, the 6.3 % growth rate that we've assumed
for nominal GDP
over the coming years will begin to bail investors out given enough time, and as a result, our projection
for 10 - year S&P 500 nominal total returns peeks its head up above zero, at about 2.4 % annually from
current levels.
The chart below provides a quick summary of our return expectations
for the S&P 500 — from
current price
levels —
over a variety of investment horizons.
The
current level implies slightly negative total returns
for the S&P 500
over the coming decade.
I expected that the shift in demand
for iron ore generated by rebalancing would cause iron ore prices within 3 - 4 years to drop by
over 50 % from their then -
current levels of around $ 180 - 90 a ton.
- Applying discounted multiples (relative to precedent industry transactions) of 10.0 x and 9.0 x our 2019E EBITDA
for the U.S. and International Networks segments, respectively, they derive an estimate of intrinsic value of $ 47 a share, representing
over 80 % upside from
current levels.
Our technical analysis is in favor of continuation of the
current bullish wave, so we can see bitcoin price reach the $ 3,800 price
level within a week or so; however, a downwards price correction attempt can take
over for a short period, before heading North to even higher
levels.
For starters, bitcoin's share of the total market has declined modestly
over the past week, from a high above 45 % to the
current level of around 43 %.
«
Over a dozen studies show
current human exposure to biologically active
levels of this chemical, creating a potential
for a variety of health implications.»
Up front we have a few world - class players surrounded by some serious pretenders... Sanchez is by far the most accomplished player in our attack but the controversy surrounding his contractual mishandling could see him go before the window closes or most definitely by season's end... obviously a mistake by both parties involved, as Sanchez's exploits have never been more on display than in North London, but the club's irresponsible wage structure and lack of real intent have been the real undoing in this mess... Lacazette, who I think has some world - class skills as a front man, will only be as good as the players and system around him, which is troubling due to our
current roster and Wenger's love of sideways passing... Walcott should have been sold years ago, enough said, and Welbeck should never have been brought in from the get - go... both of these players have suffered numerous injuries
over their respective careers and neither are good enough to overcome such difficulties: not to mention, they both are below average first - touch players, which should be the baseline test
for any player coming to a Wenger - led Arsenal team... Perez should have been played wide left or never purchased at all; what a huge waste of time and money, which is ridiculous considering our penny pinching ways and the fact that fans had been clamoring
for a real striker
for years... finally Giroud, the fact that he stills wears the jersey is a direct indictment of this club's failure to get things right... this isn't necessarily an attack on Giroud because I think he has some highly valued skills, but not
for a team that has struggled to take their sideways soccer to the next
level, as his presence slows their game even more, combined with our average, at best, finishing skills... far too often those in charge have either settled or chosen half - measures and ultimately it is us that suffer because no matter what happens Wenger, Gazidis and Kroenke will always make more money whereas we will always be the ones paying
for their mistakes... so every time someone suggests we should just shut - up and support the team just think of all the sacrifices you've made along the way and simply reply... f *** off
With four spots in the state record book already under his belt, Thompson will be working on a fifth place if he can add a little
over 1,200 yards next season and get his
current career total 3,732 yards
over the 5,000 yard entry
level mark
for that list.
over the years we've lost the opportunity to bring in talented, and innovative young managers, guys like pep, and kloop, these guys specifically had bias
for arsenal due to our philosophy of the game, and the
level of control granted our coach, this I believe has being our biggest undoing as the
current coach has
for a long time placed his ego and face before the good of the club and its fans.
But
levels of just 7 parts per billion are believed to be capable of increasing a person's blood
level over 5 micrograms per deciliter - the
current level of concern
for health.
The
current standards
for an entry -
level certified professional midwife indicate that she can begin practicing after having attended as few as 55 births
over the course of several years.
Current prices
for doula services with Melissa are $ 950-1100 and reflect the immense
level of experience and expertise and
over 15 years of learning, mentorship and commitment to the field that Melissa brings into the doula client relationship.
In a sign of increasing trouble
for Christie, his one - time mentor, former Gov. Thomas Kean, has been
leveling the sharpest criticism at the
current governor
over the bridge mess.
Its practical application, and that of the Coalition's Localism Bill, can be seen to have shifted responsibility
for delivering services and managing budgets onto the local and community
level, while effectively withholding power through enforcing cuts and strengthening government oversight, as with Gove's
current dominion
over education provision.
«With
over eighty percent of New Yorkers saying that doctors
over-prescribing opioids and allowing patients access to too many pain pills are at least somewhat responsible
for the
current level of opioid abuse, it is concerning, but not surprising, that among those that were prescribed, a quarter admit that they were given too many pills and nearly two - thirds didn't take the entire prescription.
Supportive Services Corporation Subsidized employment
for persons age 55 and
over, residents of Erie County, at / or below
current federal poverty
level.
On Wednesday, members of the city council's Progressive Caucus, including Councilman Daniel Dromm, chair of the Education Committee, came to Albany asking state legislators to adopt a budget that provides funding mandated by the Campaign
for Fiscal Equity court decision, excludes additional resources
for charter schools, leaves the charter school cap at
current levels and provides more local control
over the city's schools.
The state Board of Regents proposed allocating $ 125 million
for pre-K in its budget proposal, which asked
for a $ 1.3 billion increase
over the
current fiscal year's funding
level.
The city budget
for the
current 2016 fiscal year is
over $ 80 billion, though city reserves are at unprecendented
level, in part due to a booming city economy.
It calls
for authorizing DOE science program to spend up to $ 6.9 billion in 2018, a 49 % increase
over its
current level of $ 4.6 billion.
The new $ 7.03 billion budget
for NSF would represent a $ 173 million hike
over current, 2011
levels.
The Greenland ice sheet is thought to be one of the largest contributors to global sea
level rise
over the past 20 years, accounting
for 0.5 millimeters of the
current total of 3.2 millimeters of sea
level rise per year.
By comparison, scenarios
for fossil fuel emissions
for the 21st century range from about 600 billion tons (if we can keep total global emissions at
current levels) to
over 2500 billion tons if the world increases its reliance on combustion of coal as economic growth and population increase dramatically.
«As Ultra Street Fighter IV is coming out soon
for Steam, we are looking to transition our
current GFWL users
over to Steamworks in order to provide the optimal
level of support across the board
for PC Street Fighter fans,» writes Capcom community manager Peter Rosas.
«As Ultra Street Fighter IV is coming out soon
for Steam, we are looking to transition our
current GFWL users
over to Steamworks in order to provide the optimal
level of support across the board
for PC Street Fighter fans,»
Meeting this fourth challenge depends on more flexible ways of personalising teaching and learning —
for example, by using technology to better target individuals»
current levels of achievement and learning needs — and on defining learning success and failure in terms of the progress, or growth, that individuals make
over time, regardless of their starting points.
Washington — The Education Department's fiscal 1985 budget, scheduled to be released by the Administration in its overall budget package this week, calls
for expenditures totaling $ 15.5 billion — an increase of $ 100 million
over current levels — and a realignment of budget priorities to reflect the recommendations of the National Commission on Excellence in Education.
Developed by
over 130
current, experienced teachers
for every grade
level, the featured lessons include the teachers» reflections and insights, student work examples, and an array of other supporting materials.
Kentucky school districts are preparing budgets
for the 2004 - 05 school year on the assumption that they will receive a 2 percent increase
over current levels.
Delegates at the sessions voiced appreciation
for the graduated response under the
current system but expressed concerns
over the lack of resources that are allocated
for interventions at school action and school action plus
level.
President Bush's plan to consolidate a bevy of domestic programs into a $ 15 - billion block grant would cause a $ 27.4 billion shortfall
for states
over five years if they continue to fund the programs at their
current levels, according to a report by the Senate Budget Committee.
The fact is that most research finds, after controlling
for demographic factors, no consistent causal relationship between expenditures and achievement
over the
current range of spending
levels.
The shale gas in recent exploration in the United States, that could meet the domestic demand of the country
for natural gas at
current levels of consumption
for over 100 years, is extremely negative
for the environment because it generates half the carbon emissions from coal, and pollutes the sheets underground aquifers.
Over half (52 per cent) of secondary school leaders told us they received more applications than they could accommodate
for last year's admissions round, and the rate of growth is set to increase at secondary
level as the
current primary school population moves through the system.
First, mathematics educators have both researched and attempted to improve teacher knowledge, curriculum, and instruction
for over two decades; examining
current levels of each would provide evidence about the extent to which these goals have been met.
Example A is Pennsylvania, which recently announced they will be increasing the employer contribution rate
for retired teacher pension and health benefits in 2010 - 11 by 72 percent
over current levels.
* UPDATED Despite having laid out options to save money on health care, LA Unified has «rolled
over» and agreed to continue funding its generous benefits
for district employees, retirees, and their dependents at
current levels for the next three years.
● The budget seeks $ 375 million
for public charter schools, a $ 122 million increase
over current levels.
Teachers would get $ 350 a year
for the supplies, an increase of $ 100
over the
current level.
Over a period of several weeks, teams, with or without the help of an outside evaluator / consultant, review evidence to determine
current level of implementation and plan
for the future.
Plenty of exotic materials and modest boost
levels of just
over 1.0 - bar suggest the engine's
current output of 373kW and 550Nm (just
over 100kW / litre) leaves plenty of potential
for upgrades — be they in years to come or via different versions.
What it should be
for you depends on a number of things, including your overall financial situation (both your
current finances and how stable you expect them to be
over time), your
level of financial «education», the costs of your mortgage, the alternative investments available to you, your investing goals, and your tolerance
for risk.
While we have no idea where oil prices will settle in the short run, it remains our view that oil prices can not stay down at today's depressed prices
for too long, largely due to what we believe to be the relatively modest
current level of excess capacity, our expectations of continued growth in demand
over time, and the high marginal costs
for finding and developing new sources of supply.
«The investment return they assume
for the
current level of CPP contributions to be sustainable
over 75 years is 3.55 % in real returns, meaning after inflation,» says retirement expert and MoneySense columnist David Aston.
By the Fed's
current thinking, the «neutral» rate
for the federal funds may be as low as 3 percent, so even as rates do rise
over time, they may not get close to historic «normal»
levels.