Sentences with phrase «over cycles of»

Furthermore, there is a tendency toward approximate compensation over these cycles of loss / gain of land biosphere carbon with gain / loss of permafrost carbon (55).

Researchers have also known about and documented periodic shifts over cycles of 21,000 years, 41,000 years and 100,000 years, all of them also driven by astronomical change.

Reality: Whilst there are many areas of interesting research with respect to the glacial - interglacial cycles of the Quaternary, we have a good understanding of the primary drivers i.e. orbital variations occurring over cycles of tens of thousands of years.

Designed for investors with long - term objectives, this approach requires investing a fi xed - dollar amount at regular intervals over all cycles of the market, regardless of the price.

Actually, I believe that there is a theorem which states that over a cycle of a conservative quantity, like energy, there is an equilibrium.

Not exact matches

«Over the last couple of years [3D printing has] gone through this massive hype cycle where it's going to print you a cup and fill it with coffee,» observes Ben Wynne, chief Technology Officer at Vancouver - based Wiivv Wearables.

No matter which company you choose, it's likely valuations will rise over the next five to 10 years — the length of a typical cycle.

There are different cycles of drivers and teams that appeal to the fan base, and that changes over the years.

Apple units increased 3 % year over year and while positive it stops short of investor expectations for a super cycle,» he wrote.

It's that time of the market cycle again where we have to stop the hand - wringing over tech valuations.

Over the past decade, the company has found that the best way to stay ahead of that continuing hardware devaluation cycle is to continually create new hardware that people want.

A few months ago, NASCAR driver and cycling enthusiast Jamie McMurray rode the Assault on Mt. Mitchell, a mass participation cycling ride that covers 103 miles and includes over 11,000 feet of climbing.

If your sales cycle is longer, plan meaningful, periodic touch points over the course of a few weeks.

The debate over high drug prices has been a red hot topic here and inspired a lot of anger and legislative threats, especially in the midst of the 2016 election cycle.

Chronotypes also evolve over a person's life cycle: Teenagers are evening types; between the ages of 30 and 50, people are evenly split between morning and evening types; and people become morning types as they pass through their fifties.

A team of researchers at UCI had been experimenting with nanowires for potential use in batteries, but found that over time the thin, fragile wires would break down and crack after too many charging cycles.

They hope to be able to amass enough data about women's menstrual cycles, sexual behavior, mood, and diet that they can help any woman know exactly when to conceive, warn her about early problems like potential endometriosis, and over time, promote better health care for women in general by collecting large amounts of information that hasn't been collected before.

The answer, suggest institutional investors like Mark Wiseman, CEO of the Canadian Pension Plan Investment Board, is to align pay to longer industry and product cycles, and to use restricted stock units (rather than stock options) that vest over time — even after the CEO retires — pushing executives to think seriously about what happens after they're gone.

«In spite of the press possibly turning against podcasting [once the current hype cycle is over], podcasting will continue its steady growth.»

While the firm still has an overweight rating on technology, Wilson said the latest sell - off could be «a cautionary note about what may eventually unfold in the sector as the market starts to price in a tired cycle over the course of 2018.»

But working with new mixtures, pushing them into new materials, and seeing how safe they are over thousands of charge cycles takes a very, very long time.

The disappointing trends of the Great Recession and its aftermath come on the heels of the weak labor market from 2000 - 2007, during which the median income of non-elderly households fell significantly from $ 68,941 to $ 66,575, the first time in the post-war period that incomes failed to grow over a business cycle.

«Historically, what we've seen in past [election] cycles is that these networks lose, essentially, all of those short - term gains after the election is over,» Sweeney said.

Few cycles in major economies, Japan aside, included systemic financial stress of the type seen over the past five years.

The former VP of business development at high - end gym chain Equinox took over as CEO of SoulCycle, the sizzling hot cult cycling chain, in June.

For all his misplaced self - importance, Lindner's diagnosis last night went to the heart of German and European political divisions that are only being papered over by an admittedly strong upswing in the economic cycle.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

This cycle repeats itself over eons to form a flat terrain of finely layered sediments.

The ultimate goal of the company is to own and operate multiple franchise locations over the next 5 - 7 years, and sell the locations at the appropriate stage of its business life cycle.

As more borrowers participate, the costs of protection decline, making EPMs more attractive over traditional mortgages, and thus, spurring further participation in a cycle that will eventually lead to regional housing market stabilization.

Lenders would still be free to charge annual rates well into the triple digits, but the law would eliminate what critics say is the worst aspect of payday loans: borrowers caught in a cycle of debt by taking out loans over and over.

Partly because most inflation problems were demand driven over the course of the cycle, there was a continuing belief that if the cycle could be smoothed, inflation would be contained, and both fiscal or monetary policy were available instruments in addressing the cycle.

Since January, the platinum group metals (PGMs) have increased over a third in price, marking the end of an 18 - month bear cycle, according to Metals Focus» Platinum & Palladium Focus 2016.

As credibility builds over time, monetary policy does not have to respond to every hint of inflation, knowing that the small fluctuations in inflation over the course of the cycle will not have any permanent effects.

The critical issue here is that even though inflation rose and fell over the course of the cycle, price expectations did not move — even when inflation was running at 5 per cent, the community at large expected it would soon be back to its normal lower pace.

Such approaches could be designed to be revenue - neutral over the business cycle; they also could avoid past debates over fiscal stimulus by separating decisions on countercyclical policy from longer - run decisions about the appropriate role of the government and tax system.

Stabilising and maintaining price expectations is the key issue in thinking about the question of «over the course of the cycle».

Being both a limited partner in venture funds and a co-investor, we offer unique support to GPs over the life - cycle of the fund.

You can see this sense of priorities — with medium - term price stability being the sine qua non, and our acceptance that inflation may vary a little over the course of the cycle — in the specification of the inflation target as being an average «over the course of the cycle».

Moderate interest rates were associated with a whole range of subsequent returns over the following decade, and we know that those outcomes were 90 % correlated with the level of valuations at the beginning of those periods (on reliable measures such as market cap / GDP, price / revenue, Tobin's Q, the margin - adjusted Shiller P / E, and others we've presented over time - see Ockham's Razor and the Market Cycle).

Understand also that the evidence pointing to steep market risk over the completion of this cycle is quite robust, as the valuation criteria in the overvalued, overbought, overbullish syndromes we now observe would be satisfied even if stocks were significantly lower than they are at present.

Yet, with key economies in different stages of the business cycle, «the risk of the global economy, or any of its major constituents, running too hot over the next 12 months is contained,» says Elga Bartsch, Co-Head of Global Economics.

I've admitted my own stumbles, addressed our own challenges, and have created an open book of data and analysis to support very deep concerns about the risks that investors face over the completion of the current market cycle.

Strategies typically have over 75 percent of positions in announced transactions over a given market cycle.

When you look back on this moment in history, remember that many investors ruled out the possibility of major losses over the completion of the current market cycle because they presumed relationships that could not be established in the data, and assumed the absence of any material economic or financial shock in the coming years.

I think it's a very dangerous mistake to dispense with our present concerns by ignoring the narrative of our stress - testing response to the credit crisis, and concluding that our experience over this half - cycle has been a mechanical reflection of our pre-2009 methods, our present methods, or some perma - bearish disposition on my part.

We should not be surprised at all to see the S&P 500 back at 2010 levels or below over the completion of the present cycle.

When we began to articulate the target in the early 1990s and talked about achieving «2 — 3 per cent, on average, over the cycle», this is the sort of thing we meant.

This unfortunately dismisses the central lesson to be drawn from the awkward transition that resulted from my 2009 decision to stress - test our methods against Depression - era data, not to mention the fact that concerns similar to my present ones were rather stunningly vindicated over the completion of prior market cycles.

In my view, investors should be thinking very seriously about the extent of potential market losses over the completion of the present market cycle.