One of the people Feilding started working with was professor David Nutt, of Imperial University, whose own experience of clashing with authorities
over drug research came to a head in 2009 when he was sacked as chair of the Advisory Council of the Misuse of Drugs for ranking drugs according to the harm they do the user and society.
Not exact matches
Drug giant GlaxoSmithKline's head of
research and development, Patrick Vallance, is departing the company to head
over to the U.K. public sector.
Walmsley, who took
over a year ago, is focusing on rebuilding GSK's
drug pipeline by overhauling
research and appointing heavyweight outsiders, such as veteran Roche scientist Hal Barron.
The institute, which includes
over 40 laboratories and more than 300 researchers, said the
research would focus on modifying a patient's own immune system T - cells to target a tumor, studying ways to boost patient response to current immunotherapy
drugs.
Count all the money Valeant has spent on acquisitions as
drug research, and suddenly it has spent 200 % of its revenue
over the past five years on R&D.
Sarepta Therapeutics Inc (NASDAQ: SRPT) shares jumped up
over 17 percent during Wednesday's after - hours trading sessions, after the medical
research and
drug development company crushed earnings estimates.
Something to Sleep On
Research on infant sleep risks, which we go
over in depth in Chapter 19, shows again and again that the big risks of shared sleep are a mix of SIDS risks that affect vulnerable babies and breathing hazards that affect all babies: smoking, alcohol or
drugs, risky surfaces like sofas, baby on his front (unless he's on an adult's chest), and formula - feeding.
The Youth Initiative for
Drug Research Information Support and Education, otherwise known as Youth Rise and the All Progressives Congress (APC) Youth Connect have lauded the President of the Senate, Dr. Abubakar Bukola Saraki, over his new initiative aimed at addressing and solving the prevalence of drug abuse in many parts of Nige
Drug Research Information Support and Education, otherwise known as Youth Rise and the All Progressives Congress (APC) Youth Connect have lauded the President of the Senate, Dr. Abubakar Bukola Saraki,
over his new initiative aimed at addressing and solving the prevalence of
drug abuse in many parts of Nige
drug abuse in many parts of Nigeria.
That, noted the
research's author Max Chambers, is equivalent to «an estimated 73,000 prisoners
over the course of a year whose
drug habits are effectively being maintained by the state.»
Over the past year, Kaloyeros has been working with local officials, including those at the Buffalo Niagara Medical Campus, to develop plans announced by Cuomo in December to invest $ 50 million in state funds to build and equip a pharmaceutical
drug research and development center at the downtown medical campus.
While average life expectancy has been rising steadily in most countries
over the past century, new
research led by the Centre for Addiction and Mental Health (CAMH) shows that life expectancy declined significantly and rapidly in three countries where policy changes increased access to prescription opioids, alcohol or illicit
drugs.
Such
drugs are often sold as «legal» highs or «
research chemicals»
over the internet or in head shops.
Botulinum toxin has undergone a number of reincarnations
over the years, from a contaminant in improperly prepared foods, to a laboratory
research tool to probe nerve - muscle communication, to a
drug to treat problems involving eyes, muscles, and excessive sweating to, most famously, a
drug that combats wrinkles for cosmetic purposes.
In science news around the world, NASA's Cassini mission is about to take its final plunge into the atmosphere of Saturn after 13 years providing an unprecedented view of the planet and its moons, a fight
over whether to preserve or develop of one Europe's oldest gold mining sites heats up again, the U.S. Food and
Drug Administration approves the first cancer gene therapy for people, a U.S. court gives a green light to a $ 1 billion lawsuit brought by the Guatemalan victims and survivors of mid — 20th century syphilis experiments by
research institutions including Johns Hopkins University, and more.
Much clinical
research will be needed to determine whether those
drugs are safe
over a long period and have therapeutic benefits for people with Down syndrome,» said Sullivan.
Promega, headquartered in Madison, Wisconsin, has nearly a thousand employees worldwide and manufactures
over two thousand products, consisting of kits and reagents as well as integrated solutions for life science
research and
drug discovery, genetic identity, and clinical diagnostics.
Until recently the only treatments available for conditions affecting the brain were
drugs or surgery — a «hammer
over the head approach», according to William Tyler, a biomedical engineer at Virginia Tech Carilion
Research Institute in Roanoke and a pioneer of the new brain stimulation techniques.
Over a year's time, these patients experienced about half as many flare - ups as those taking another commonly prescribed
drug, a different
research group reported in the same issue of the journal.
Recent hullabaloo
over drug companies paying for ghostwritten medical journal articles — that doctors later sign their names to — has raised questions about a wealth of hidden financial arrangements in the medical
research community.
«There is no one blood or oral fluid concentration that can differentiate impaired and not impaired,» says Marilyn Huestis, who spent
over 20 years leading cannabinoid - related
research projects at the National Institute on
Drug Abuse.
But his
research over the years has soured him on the
drugs, suggesting they work only marginally better in the average patient than a placebo pill.
Over her time at FDA, Woodcock has moved up, first by running the review group for biologics, then becoming the deputy director of biologics, then head of the Office of Therapeutics, and finally being appointed head of the Center for
Drug Evaluation and
Research (CDER), a division of FDA committed to ensuring that «all prescription and
over-the-counter
drugs are safe and effective.»
Despite concerns
over the rising use of antipsychotic
drugs to treat young people, little has been known about trends and usage patterns in the United States before this latest
research, which was funded by the National Institute of Mental Health (NIMH), part of the National Institutes of Health.
Children and young people admitted to hospital in England with injuries related to self - harming,
drugs or alcohol faced an increased risk of killing themselves
over the following 10 years, according to new
research.
The work builds on the success of the Lincoln team's pioneering
research to tackle antimicrobial resistance
over the past 22 months to turn teixobactin into a viable
drug.
«We've been continually successful,
over time, in developing new
drugs,» says Richard Gregory, head of
research at Genzyme.
A psychiatrist whose failure to disclose
drug company income contributed to a furor
over conflicts of interest in biomedical
research has just received his first National Institutes of Health (NIH) grant in 3 years.
The team from the Arthritis
Research UK Centre for Epidemiology looked at data from
over 15,000 patients diagnosed with the disease who were being treated with certain types of immunosuppressive
drugs, and found that one in five patients received no influenza vaccinations and one in two patients received no pneumonia vaccine
over a five year follow - up period.
Basic
research on cancer mechanisms has led to
over 40 targeted cancer therapies currently on the market, which take the form of monoclonal antibodies, small molecule
drugs, and immunotherapies.
The University of Sheffield and a
research radiologist there are fighting
over whether the scientist had permission from her bosses and a
drug company to submit her osteoporosis work to a conference this summer.
This means that the company has more control
over the day - to - day science, but also that the
research is more likely to contribute to a successful
drug, device or product.
«
Over the last few years, our
research group has been working on the development of novel
drug delivery systems for the treatment of several skin and eye diseases,» said Prof. Lopez.
Yet
research and clinical observations
over the past 40 years have raised concerns that these
drugs produce suicidal thoughts, suicide attempts and possibly even suicide in a small subset of depressed patients.
The study, led by a team in The
Research Institute at Nationwide Children's Hospital, is the first of its kind to show these results from an exon - skipping
drug — a class of therapeutics that allows cells to skip
over missing parts of the gene and produce protein naturally.
The study adds to previous
research by lead investigator Kalyani Sonawane, Ph.D., demonstrating that the
drug treatment, which combines two
drugs in a single pill, known as fixed - dose combination, has several advantages
over other approaches for adjusting blood pressure medication.
«
Over 400,000 people die of malaria each year, and resistance to common antimalarial
drugs is growing,» says Professor Mike Blackman, Group Leader at the Francis Crick Institute, who led the
research.
Over the past decade, high - content analysis (HCA) has become widely adopted in both academic
research and
drug discovery laboratories.
Press reports
over the last 15 years detail how whistle - blowers inside academia and within the FDA who have attempted to expose
drug -
research and safety issues have been pressured.
Indeed, earlier
research at Penn identified that a majority of prescription
drugs act on enzymes and proteins that oscillate
over 24 hours.
The
research team, led by Renee Goodwin, PhD, in the Department of Epidemiology, analyzed data from the National Household Survey on
Drug Use, an annual cross-sectional study of approximately 497, 000 Americans, ages 12 and
over.
«
Over the past five to 10 years, types of illicit
drugs used around the world have been created or repurposed from
research chemicals to mimic the effects of traditional
drugs of abuse in order to circumvent legal control and detection,» explained corresponding author Sabra Botch - Jones, MS, MA, D - ABFT, forensic toxicologist and instructor in the Biomedical Forensic Sciences program in the department of anatomy and neurobiology at BUSM.
Due to its relatively high prevalence, the disabling nature of temporal lobe seizures, and the difficulty of treating with
drugs, there has been much
research study on this type of epilepsy, particularly
over the past 20 years.
Based on our findings, the occurrence of cancer is much higher in adults
over 75 years of age compared with the proportion of patients in this age group who enroll in clinical trials,» said lead study author Bindu Kanapuru, MD, medical officer in the Division of Hematology Products, Office of Hematology and Oncology Products in the US Food and
Drug Administration's (FDA) Center for
Drug Evaluation and
Research, who presented the results at the 59th American Society of Hematology (ASH) Annual Meeting and Exposition, held December 9 — 12 in Atlanta.
She has
over 10 years of experience in the
research field in various areas including clinical trials studies, neuroimaging studies,
drug addiction, and developmental psychology.
With an
over $ 70 million commitment
over multiple years from the NIH and the Wellcome Trust, H3Africa is designed to create and support a pan-continental network of labs that will be equipped to apply leading - edge
research to the study of the genetic and environmental basis of disease susceptibility and
drug responses in Africans.
Rudolf will receive more than $ 900,000
over five years to support his
research on discovering new
drugs from natural resources using cytochrome P450 enzymes.
The
research group conducted high throughput screening of
over 1000 compounds consisting of existing
drugs, including those approved by the Food and
Drug Administration (FDA) of USA, Europe or Asia, and
drugs under clinical trial, to search for
drugs that can regulate the circadian rhythm in mammals.
Over the past five years oncology
research has exploded, with fast - paced development schedules delivering breakthrough
drugs that are changing the standard of care.
One key aspect that her
research group has devoted its efforts to
over the past 15 years is expanding the toolkit of building blocks to include fluorinated aliphatic amino acids to improve the pharmacokinetic and physicochemical profiles of peptide / protein - based
drugs and materials, respectively.
Furthermore, the need to watch
over the patient, «for hours after treatment may make this an impractical
drug to clinically use and further
research into dosages is required,» Manevitz said.