Sentences with phrase «over duration risk»

These ETFs, now available for the municipal, corporate and high yield sectors, enable more precise control over duration risk than previous fixed income ETF offerings.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
This is the process by which we put our research to work using the levers of credit risk and duration to make money in the bond market and to stabilize returns over the cycle.
Return on equity should continue to grow over the next three to five years, especially as the company expands its reinsurance portfolio to take on longer - duration risks in an effort to spur results.
Longer duration of breastfeeding may or may not affect the appearance of your breasts, but it will reduce the risk for breast cancer over your lifetime, in addition to the many other health benefits to you and to your breastfed baby.
A longer duration of breastfeeding — for example more than 12 months (and this can be over several babies) is more protective, even if you are breastfeeding at all and whether you are mixed feeding with some breast milk and some formula, your breast cancer risks are reduced.
In a new study of over 7,000 older Chinese women published online today in the journal Rheumatology, breastfeeding — especially for a longer duration — is shown to be associated with a lower risk of rheumatoid arthritis (RA).
The risk jumps sevenfold for a first - time mother and tenfold in pregnancies over 41 weeks in duration.
In a new study of over 7,000 older Chinese women published online today in the journal Rheumatology, breastfeeding — especially for a longer duration — is shown to be associated with a lower risk of rheumatoid arthritis (RA).
An increased risk of intense, short - duration rainfall events in mid-latitude regions has been predicted consistently for well over a decade as part of the pattern of human influence on precipitation.
The longitudinal study analyzed the association of aspirin, with varied doses and duration of use, on overall mortality risks and mortality risks from cancer over a nearly 32 - year period.
For that reason, many looking at carry trading strategies will have to go out over the risk curve and borrow in a cheap major currency in order to buy a higher - yielding emerging market (EM) currency in order to earn a yield beyond that of higher - duration US Treasury bonds (considered safe yield).
Rising rates could, over time, help restore the attractiveness of lower - risk government and shorter - duration debt — at the expense of more richly valued credit sectors that have benefited from the hunt for yield in recent years.
While negative numbers are seen across the board, the above table of duration and return doesn't truly highlight the magnitude of interest rate risk hanging over the market.
Tobacco settlement bonds tracked by the S&P Municipal Bond Tobacco Index are down nearly 9 % year to date as yields have risen by over 255bps as the credit risk of these long duration bonds is questioned.
With discipline honed over decades of managing money through various market environments, Baird Advisors consistently applies its process to control risk and add incremental value to portfolios across the duration spectrum.
We believe the bond market is very efficient in discounting risk and return potential over time and in taking interest rate risk along the duration curve.
Actively managed bond funds have the people, data and tools for credit selection, can adjust for term structure and duration risk and have control over the timing of bond purchases and sales.
Data from Cerulli and BlackRock also shows bond ETF use generally «starts with broad - based core holdings,» but over time sophisticated users of bond ETF products may shift to more specialized investment objectives, such as managing sector exposure, duration, maturities, and credit risk according to unique client needs.
In general, the risk of aerosol transmission increases with proximity and duration of exposure to the source; however, once aerosolized, certain pathogens may remain infective over long distances, depending on particle size, the nature of the pathogen, and such environmental factors as temperature and humidity.3
By investing in real estate, the risk you assume is minimized with tangible assets that don't significantly change in value over short periods of time not to mention real estate generates steady monthly cash flow each month for the duration of the investment.
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